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The map label for this gene is tsf

Identifier: 23099042

GI number: 23099042

Start: 1623427

End: 1624311

Strand: Direct

Name: tsf

Synonym: OB1587

Alternate gene names: 23099042

Gene position: 1623427-1624311 (Clockwise)

Preceding gene: 23099041

Following gene: 23099043

Centisome position: 44.72

GC content: 36.16

Gene sequence:

>885_bases
ATGGCTATTACTGCACAAATGGTTAAAGAATTACGTGAAAAAACTGGTGCTGGAATGATGGATTGTAAAAAAGCACTACA
AGAAACGAATGGTGATATTGAACAGGCAATTGATTTTCTTCGTGAAAAAGGAATGGCGAAAGCTGCGAAAAAAGCAGATC
GTGTAGCAGCAGAAGGATTAACTCATATTGAGGTTGAAGGTAATAAAGCTGCAATAATTGAAGTTAATTGTGAAACTGAC
TTTGTTACAAAAAACGATCAGTTCAAACAATTGTTAAGTGAGCTTGGTAAGCATATTGTTGCAAATGAACCAGCGACAGT
TGAAGAAGCTCTTCAACAAAAACTTCATGGAGATGGAGAAACAGTTGAATCTGTAATCACAAACGCAGTTGCAAAAATTG
GTGAGAAAATTTCCTTACGTCGTTTTGAAGTACTAGAAAAAACTGATAACGATGCATTTGGTGCTTACTTGCACATGGGT
GGTACTATTGGTGTACTATCATTGTTAGAAGGTACTACAGATGAACAAGTTGGAAAAGATATCGCTATGCACGTTGCAGC
AGTAAATCCTCGTTATGTAACTCGTGATGAAGTTGCTGAAGAAGAAGTGAATCGTGAACGTGAAGTGTTGAAAACACAAG
CATTAAATGAAGGTAAACCAGAGAATATTGTTGAGAAAATGGTTGAAGGTCGTCTTGGTAAATTCTTTGAAGACATCGTA
TTATTAGAACAAAGCTTCGTTAAAGATCCAGACCAAAAAGTGAAAAAATATGTAGCTGATAAAGGTGCGGCTGTAAAAAC
ATTTGTTCGTTATGAAGTAGGCGAAGGAATGGAAAAACGCGAAGAAAACTTCGCTGAAGAAGTAATGAGTCAAATTAAAA
AATAG

Upstream 100 bases:

>100_bases
CAAGAGTAATCATTGAAAAGGTGAGGGTGATAAGAGGATTGAAGCCTTTTATCACCCTTTTTTAAAAGAAACTAATTATT
GAATCTAAGGAGGATCATAC

Downstream 100 bases:

>100_bases
TTGCAACAAATTAGGGGACATTAATTTGTTCCCTATTTTGGCAAGTAAAGGATATATTTTTTCTTGCTATATGATTATTA
CCGAATACTTTTATCGTTTG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAITAQMVKELREKTGAGMMDCKKALQETNGDIEQAIDFLREKGMAKAAKKADRVAAEGLTHIEVEGNKAAIIEVNCETD
FVTKNDQFKQLLSELGKHIVANEPATVEEALQQKLHGDGETVESVITNAVAKIGEKISLRRFEVLEKTDNDAFGAYLHMG
GTIGVLSLLEGTTDEQVGKDIAMHVAAVNPRYVTRDEVAEEEVNREREVLKTQALNEGKPENIVEKMVEGRLGKFFEDIV
LLEQSFVKDPDQKVKKYVADKGAAVKTFVRYEVGEGMEKREENFAEEVMSQIKK

Sequences:

>Translated_294_residues
MAITAQMVKELREKTGAGMMDCKKALQETNGDIEQAIDFLREKGMAKAAKKADRVAAEGLTHIEVEGNKAAIIEVNCETD
FVTKNDQFKQLLSELGKHIVANEPATVEEALQQKLHGDGETVESVITNAVAKIGEKISLRRFEVLEKTDNDAFGAYLHMG
GTIGVLSLLEGTTDEQVGKDIAMHVAAVNPRYVTRDEVAEEEVNREREVLKTQALNEGKPENIVEKMVEGRLGKFFEDIV
LLEQSFVKDPDQKVKKYVADKGAAVKTFVRYEVGEGMEKREENFAEEVMSQIKK
>Mature_293_residues
AITAQMVKELREKTGAGMMDCKKALQETNGDIEQAIDFLREKGMAKAAKKADRVAAEGLTHIEVEGNKAAIIEVNCETDF
VTKNDQFKQLLSELGKHIVANEPATVEEALQQKLHGDGETVESVITNAVAKIGEKISLRRFEVLEKTDNDAFGAYLHMGG
TIGVLSLLEGTTDEQVGKDIAMHVAAVNPRYVTRDEVAEEEVNREREVLKTQALNEGKPENIVEKMVEGRLGKFFEDIVL
LEQSFVKDPDQKVKKYVADKGAAVKTFVRYEVGEGMEKREENFAEEVMSQIKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=303, Percent_Identity=27.7227722772277, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI291084500, Length=324, Percent_Identity=26.8518518518519, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI291084498, Length=98, Percent_Identity=40.8163265306122, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI291084502, Length=98, Percent_Identity=40.8163265306122, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786366, Length=292, Percent_Identity=45.8904109589041, Blast_Score=224, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17561440, Length=301, Percent_Identity=27.2425249169435, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19921466, Length=288, Percent_Identity=28.8194444444444, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_OCEIH (Q8EQV2)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692508.1
- ProteinModelPortal:   Q8EQV2
- SMR:   Q8EQV2
- GeneID:   1017975
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1587
- NMPDR:   fig|221109.1.peg.1589
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   OIHE221109:OB1587-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 32660; Mature: 32528

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITAQMVKELREKTGAGMMDCKKALQETNGDIEQAIDFLREKGMAKAAKKADRVAAEGL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
THIEVEGNKAAIIEVNCETDFVTKNDQFKQLLSELGKHIVANEPATVEEALQQKLHGDGE
CEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
TVESVITNAVAKIGEKISLRRFEVLEKTDNDAFGAYLHMGGTIGVLSLLEGTTDEQVGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
IAMHVAAVNPRYVTRDEVAEEEVNREREVLKTQALNEGKPENIVEKMVEGRLGKFFEDIV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLEQSFVKDPDQKVKKYVADKGAAVKTFVRYEVGEGMEKREENFAEEVMSQIKK
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AITAQMVKELREKTGAGMMDCKKALQETNGDIEQAIDFLREKGMAKAAKKADRVAAEGL
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
THIEVEGNKAAIIEVNCETDFVTKNDQFKQLLSELGKHIVANEPATVEEALQQKLHGDGE
CEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
TVESVITNAVAKIGEKISLRRFEVLEKTDNDAFGAYLHMGGTIGVLSLLEGTTDEQVGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
IAMHVAAVNPRYVTRDEVAEEEVNREREVLKTQALNEGKPENIVEKMVEGRLGKFFEDIV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLEQSFVKDPDQKVKKYVADKGAAVKTFVRYEVGEGMEKREENFAEEVMSQIKK
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376