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The map label for this gene is codY

Identifier: 23099006

GI number: 23099006

Start: 1594664

End: 1595443

Strand: Direct

Name: codY

Synonym: OB1551

Alternate gene names: 23099006

Gene position: 1594664-1595443 (Clockwise)

Preceding gene: 23099005

Following gene: 23099007

Centisome position: 43.92

GC content: 36.03

Gene sequence:

>780_bases
ATGGATTTATTAAGTAGAGCAAGAAAAATCAATGCAATGTTACAAACAGCAACAGGAAAGTCAGTGAATTTTAACGAAAT
GTCTGCATCGTTACGCGACGTTATTCGTGGTAATGTTTATATTGTAAGTAGACGTGGGAAATTATTAGGTTTTGCTGTAA
ATCAAGAGATTGAGAACGAGCGTATGAAATCAATGCTGGAAGAGCGTCAATTCCCAGAAGAATATACAAGAGGATTACAC
GATATTCGTGAAACTACTCCAAACTTGGATATCGAAAGTACTCATACCGTTTTCCCAGTAGAAAATAAAGAATTATTTAA
AGATGGACTTACTACAATTGTCCCAATTATCGGTGGTGGAGAACGTCTAGGTACGTTAATTCTAGGAAGAGTTAATGAAA
GCTTTAGTGATGATGACTTACTATTAGGTGAATATGGTGCAACAGTGGTAGGAATGGAAATTCTTCATGAGAAAACCGAA
GAAATTGAAATGGAAGCACGTAGCAAAGCTGTAGTACAAATGGCGATTAGTTCCCTTTCTTACAGTGAATTAGAAGCTAT
CGACCATATCTTCGAAGAACTAAACGGTAAAGAAGGATTGCTTGTTGCTAGTAAAATCGCAGATCGCGTTGGAATTACTC
GTTCCGTAATTGTTAATGCACTACGTAAGTTAGAGAGTGCTGGAGTAATTGAGTCTCGTTCGCTTGGTATGAAAGGTACG
TACATTAAAGTACTAAATGATAAATTCTTAGTAGAATTAGAAAAATTACGTTCAAGATAA

Upstream 100 bases:

>100_bases
TACAGTTGGTTATGTCGATGATAAACTATCATCTATTGTTCAAGATAAAGATTTAAGCCAATTCATACTATAATTTTAAA
TATCGAATGGAGGAAATATC

Downstream 100 bases:

>100_bases
GTACTGCTTTTATAGCGGTGTTCAAAAAACAGTGGTTTATGTTGAAAATTTGTATATAATGTAAAATTTTCACAAATATG
TTAAAGAGTCGATGAAAATC

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENERMKSMLEERQFPEEYTRGLH
DIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGGERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTE
EIEMEARSKAVVQMAISSLSYSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLVELEKLRSR

Sequences:

>Translated_259_residues
MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENERMKSMLEERQFPEEYTRGLH
DIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGGERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTE
EIEMEARSKAVVQMAISSLSYSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLVELEKLRSR
>Mature_259_residues
MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENERMKSMLEERQFPEEYTRGLH
DIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGGERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTE
EIEMEARSKAVVQMAISSLSYSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLVELEKLRSR

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_OCEIH (P59386)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692472.1
- ProteinModelPortal:   P59386
- GeneID:   1017837
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1551
- NMPDR:   fig|221109.1.peg.1553
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- BioCyc:   OIHE221109:OB1551-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 28975; Mature: 28975

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHHHHHH
RMKSMLEERQFPEEYTRGLHDIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCHHHHHHHCCCC
ERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTEEIEMEARSKAVVQMAISSLS
HHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YIKVLNDKFLVELEKLRSR
EEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHHHHHH
RMKSMLEERQFPEEYTRGLHDIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCHHHHHHHCCCC
ERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTEEIEMEARSKAVVQMAISSLS
HHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YIKVLNDKFLVELEKLRSR
EEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376