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The map label for this gene is sucD [H]

Identifier: 23098999

GI number: 23098999

Start: 1586715

End: 1587617

Strand: Direct

Name: sucD [H]

Synonym: OB1544

Alternate gene names: 23098999

Gene position: 1586715-1587617 (Clockwise)

Preceding gene: 23098998

Following gene: 23099000

Centisome position: 43.7

GC content: 41.31

Gene sequence:

>903_bases
ATGAGTGTTTATATTAATAAAGATACAAAAGTGATTGTCCAAGGAATTACTGGTGGCACTGCACGTTTTCACACAAAACA
AATGCTAGAATACGGTACAAAAATCGTTGCAGGTGTAACGCCTAAAAAAGGAGGTACAGAAGTTGAGGGAGTACCGGTAT
ATAATACGGTTAAAGATGCTGTAGACGCTACTGGTGCTACTGCTTCAGTTATTTATGTGCCTGCACCTTTTGCGGCTGAT
GCTATTTTAGAAGCAACGGATGCAGAATTAGATCTAGTTATTTGTATCACGGAACATATTCCTGTTATGGACATGGTAAA
AGTGAAGCGTTATATGGAAGGCAAGAAAACTCGCCTTGTGGGTCCAAACTGTCCTGGTGTAATCACTGCAGATGAAACCA
AAATAGGAATTATGCCTGGATATATCCACAAGAAAGGTCATATCGGTGTAGTTTCCCGTTCTGGAACATTAACATATGAA
GCTGTACATCAACTGTCTGAAGCCGGTTATGGCCAAACTACAGCAGTCGGTATCGGTGGAGACCCTGTAAATGGCACGAA
CTTTATCGATGTGTTGGATGCATTTAATCAGGATCCAGAAACAGAAGCAGTAATCATGATTGGTGAAATCGGCGGTACTG
CAGAAGAAGAAGCTGCTGAATGGGTGAAGGCAAATATGAATAAACCTGTTGTTGGCTTTATTGGTGGAGCAACTGCACCT
CCTGGAAAACGTATGGGACATGCTGGTGCAATCATCTCTGGCGGAAAAGGTACGGCGGATGAGAAAATACGTACGATGGA
AGCCGCAGGCATTAAAGTAGCAGATACTCCTGCTGTTATGGGTGAAACAATGATTAAAGCATTAAAAGAAAATGGTTTAG
ATGAAAAATGTAAAACACATTAA

Upstream 100 bases:

>100_bases
TACTGCAACATCTATGGCTGATGGAGCAGAGAAAATTGTTGCTGCAGTAAAATAAACTTAGTAAACCGAGAACTTTACAA
AGAGGAAAGGACGGACGAAA

Downstream 100 bases:

>100_bases
TTAAAGAATAGAGATTGGGATATTTTATACAAAAATGGGTGATTTTGTATGAGTTCTTAAATTCCAATCTCTATTTTCCA
TATAACTTAATTTGTCATTG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSVYINKDTKVIVQGITGGTARFHTKQMLEYGTKIVAGVTPKKGGTEVEGVPVYNTVKDAVDATGATASVIYVPAPFAAD
AILEATDAELDLVICITEHIPVMDMVKVKRYMEGKKTRLVGPNCPGVITADETKIGIMPGYIHKKGHIGVVSRSGTLTYE
AVHQLSEAGYGQTTAVGIGGDPVNGTNFIDVLDAFNQDPETEAVIMIGEIGGTAEEEAAEWVKANMNKPVVGFIGGATAP
PGKRMGHAGAIISGGKGTADEKIRTMEAAGIKVADTPAVMGETMIKALKENGLDEKCKTH

Sequences:

>Translated_300_residues
MSVYINKDTKVIVQGITGGTARFHTKQMLEYGTKIVAGVTPKKGGTEVEGVPVYNTVKDAVDATGATASVIYVPAPFAAD
AILEATDAELDLVICITEHIPVMDMVKVKRYMEGKKTRLVGPNCPGVITADETKIGIMPGYIHKKGHIGVVSRSGTLTYE
AVHQLSEAGYGQTTAVGIGGDPVNGTNFIDVLDAFNQDPETEAVIMIGEIGGTAEEEAAEWVKANMNKPVVGFIGGATAP
PGKRMGHAGAIISGGKGTADEKIRTMEAAGIKVADTPAVMGETMIKALKENGLDEKCKTH
>Mature_299_residues
SVYINKDTKVIVQGITGGTARFHTKQMLEYGTKIVAGVTPKKGGTEVEGVPVYNTVKDAVDATGATASVIYVPAPFAADA
ILEATDAELDLVICITEHIPVMDMVKVKRYMEGKKTRLVGPNCPGVITADETKIGIMPGYIHKKGHIGVVSRSGTLTYEA
VHQLSEAGYGQTTAVGIGGDPVNGTNFIDVLDAFNQDPETEAVIMIGEIGGTAEEEAAEWVKANMNKPVVGFIGGATAPP
GKRMGHAGAIISGGKGTADEKIRTMEAAGIKVADTPAVMGETMIKALKENGLDEKCKTH

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=296, Percent_Identity=60.8108108108108, Blast_Score=305, Evalue=4e-83,
Organism=Homo sapiens, GI38569421, Length=255, Percent_Identity=27.0588235294118, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=62.6297577854671, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=63.6986301369863, Blast_Score=353, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=60.2739726027397, Blast_Score=331, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=47.4402730375427, Blast_Score=259, Evalue=4e-70,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=53.7671232876712, Blast_Score=326, Evalue=9e-90,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=58.5034013605442, Blast_Score=311, Evalue=3e-85,
Organism=Drosophila melanogaster, GI281363477, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281363475, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281363473, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31427; Mature: 31296

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00318 HMG_COA_REDUCTASE_2 ; PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYINKDTKVIVQGITGGTARFHTKQMLEYGTKIVAGVTPKKGGTEVEGVPVYNTVKDA
CEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
VDATGATASVIYVPAPFAADAILEATDAELDLVICITEHIPVMDMVKVKRYMEGKKTRLV
HHCCCCCEEEEEECCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADETKIGIMPGYIHKKGHIGVVSRSGTLTYEAVHQLSEAGYGQTTAVGIGG
CCCCCEEEEECCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCC
DPVNGTNFIDVLDAFNQDPETEAVIMIGEIGGTAEEEAAEWVKANMNKPVVGFIGGATAP
CCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCC
PGKRMGHAGAIISGGKGTADEKIRTMEAAGIKVADTPAVMGETMIKALKENGLDEKCKTH
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
SVYINKDTKVIVQGITGGTARFHTKQMLEYGTKIVAGVTPKKGGTEVEGVPVYNTVKDA
EEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
VDATGATASVIYVPAPFAADAILEATDAELDLVICITEHIPVMDMVKVKRYMEGKKTRLV
HHCCCCCEEEEEECCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADETKIGIMPGYIHKKGHIGVVSRSGTLTYEAVHQLSEAGYGQTTAVGIGG
CCCCCEEEEECCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCC
DPVNGTNFIDVLDAFNQDPETEAVIMIGEIGGTAEEEAAEWVKANMNKPVVGFIGGATAP
CCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCC
PGKRMGHAGAIISGGKGTADEKIRTMEAAGIKVADTPAVMGETMIKALKENGLDEKCKTH
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]