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The map label for this gene is lepB [H]

Identifier: 23098993

GI number: 23098993

Start: 1580833

End: 1581414

Strand: Direct

Name: lepB [H]

Synonym: OB1538

Alternate gene names: 23098993

Gene position: 1580833-1581414 (Clockwise)

Preceding gene: 23098992

Following gene: 23098994

Centisome position: 43.54

GC content: 37.46

Gene sequence:

>582_bases
ATGGCTAGGGATAAAGAAAATAAAAAGAAAAACGAGTGGTTAGATTGGATCAAAGCACTATTAGTAGCTTTTGGACTGGC
ATTTCTTGTACGAATGTTCCTATTTGCACCAATAATAGTTGAAGGACCGTCGATGTTCCCGACGTTGCACGACCGTGATC
AAATGATTGTAAATAAATTATCTTATACAATTGGTGAGCCAGAACGATTTGATATTGTTGTGTTTCATGCACCTACCCAA
AAAGATTTCATCAAAAGAATTATCGCTTTACCAGGGGAGCATGTAGCTGTGGAAGATAATAAATTGTACATTAATGGAGA
AGAAGTAGAAGAACCGTTTCTTAATGAACAAAAAGAGAACTTGCAATCTTACCAAACACTGACGAATGATTTTACATTGG
AACAACTTCCAGGAAATTATGATGTAGTGCCAGAAGGGCATGTGTTCGTATTAGGAGATAATCGCAGTAATTCTACCGAT
TCGCGTATGATAGGTGTTGTACCAATGGAAGAGCTAGTGGGAGAAGCAAGCTTTGTTTACTGGCCATTTGATCGAATTCA
TCTGATAGGAAAAGGAGAATAA

Upstream 100 bases:

>100_bases
GCAGAAGCTCCTTTTTACTTATCTATTATATTTGAGTTGTCTAGAATCATATATATAGCTTACAATATATAGTAGAAAGA
TAAGACACGGAGGGGACTGG

Downstream 100 bases:

>100_bases
TAATGGCTATACAATGGTTTCCAGGCCATATGGCAAAAGCAAAAAGAGAAGTAGAAGAGAAATTAAAATTAGTTGATTTT
GTAATCGAATTAGTAGATGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MARDKENKKKNEWLDWIKALLVAFGLAFLVRMFLFAPIIVEGPSMFPTLHDRDQMIVNKLSYTIGEPERFDIVVFHAPTQ
KDFIKRIIALPGEHVAVEDNKLYINGEEVEEPFLNEQKENLQSYQTLTNDFTLEQLPGNYDVVPEGHVFVLGDNRSNSTD
SRMIGVVPMEELVGEASFVYWPFDRIHLIGKGE

Sequences:

>Translated_193_residues
MARDKENKKKNEWLDWIKALLVAFGLAFLVRMFLFAPIIVEGPSMFPTLHDRDQMIVNKLSYTIGEPERFDIVVFHAPTQ
KDFIKRIIALPGEHVAVEDNKLYINGEEVEEPFLNEQKENLQSYQTLTNDFTLEQLPGNYDVVPEGHVFVLGDNRSNSTD
SRMIGVVPMEELVGEASFVYWPFDRIHLIGKGE
>Mature_192_residues
ARDKENKKKNEWLDWIKALLVAFGLAFLVRMFLFAPIIVEGPSMFPTLHDRDQMIVNKLSYTIGEPERFDIVVFHAPTQK
DFIKRIIALPGEHVAVEDNKLYINGEEVEEPFLNEQKENLQSYQTLTNDFTLEQLPGNYDVVPEGHVFVLGDNRSNSTDS
RMIGVVPMEELVGEASFVYWPFDRIHLIGKGE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22200; Mature: 22068

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDKENKKKNEWLDWIKALLVAFGLAFLVRMFLFAPIIVEGPSMFPTLHDRDQMIVNKL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SYTIGEPERFDIVVFHAPTQKDFIKRIIALPGEHVAVEDNKLYINGEEVEEPFLNEQKEN
HHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCEEEECCHHHHCHHHHHHHHH
LQSYQTLTNDFTLEQLPGNYDVVPEGHVFVLGDNRSNSTDSRMIGVVPMEELVGEASFVY
HHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHHHCCCEEEE
WPFDRIHLIGKGE
ECHHHEEEEECCC
>Mature Secondary Structure 
ARDKENKKKNEWLDWIKALLVAFGLAFLVRMFLFAPIIVEGPSMFPTLHDRDQMIVNKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SYTIGEPERFDIVVFHAPTQKDFIKRIIALPGEHVAVEDNKLYINGEEVEEPFLNEQKEN
HHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCEEEECCHHHHCHHHHHHHHH
LQSYQTLTNDFTLEQLPGNYDVVPEGHVFVLGDNRSNSTDSRMIGVVPMEELVGEASFVY
HHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHHHCCCEEEE
WPFDRIHLIGKGE
ECHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]