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The map label for this gene is ftsY [H]

Identifier: 23098984

GI number: 23098984

Start: 1574720

End: 1575721

Strand: Direct

Name: ftsY [H]

Synonym: OB1529

Alternate gene names: 23098984

Gene position: 1574720-1575721 (Clockwise)

Preceding gene: 23098983

Following gene: 23098985

Centisome position: 43.37

GC content: 35.63

Gene sequence:

>1002_bases
ATGGGATTTATGGATAAGTTAAAGCAAAAATTTAAGCAAGATAATGAAACAAAACAAGTTACAGAAAAGTATCAAGAAGG
AATGAAAAAAACACGTAATTCTTTTTCTGGAAAATTAAATGATTTAATTGCTCGTTATCGTAAAGTAGATGAGGATTTTT
TTGAAGAACTAGAAGAAGTACTTATTACTGCAGACGTTGGTGTTACAACGGTTATGGATCTTGTCGAAGAGCTAAAAATG
GAAGTTAAGCGTCAAAATATAAAAGATTCAGAGCAAATAAAAGACGTTATCTCCGAGAAACTTGTTGAGATCTATTACGG
AGATGAAGATGAATCGATTGAAAAACTGAAAATAGATGGTGATGGCTTAAAAGTTATATTGGTTGTTGGAGTAAATGGTG
CGGGTAAAACAACAAGTATTGGAAAGCTGGCACATCAGCTAAAGCAAGAAGGAAAGAATGTCGTGTTAGCTGCAGGAGAT
ACTTTTCGTGCAGGTGCAATAGAACAATTAGAAGTGTGGGGAGAACGTGCAGATGTCCCTGTAATTAAACAAAGCGAAGG
TAGTGACCCGGCTGCTGTAATCTATGATGGGGTTCAAGCTGCAAAATCACGTAATGCAGATGTCTTGATCTGTGACACGG
CTGGTAGATTACAAAACAAAGTTAATTTAATGAATGAATTATCGAAAGTAAAACGTGTGATAGAGCGAGAAATTCCAGAT
GCACCTCATGAGGTGTTGTTGGTATTAGATGCTACAACTGGTCAAAACGCGCTTAATCAAGCACGTACATTCTCTGATGC
TACGGATGTTACTGGAATTGTATTAACAAAATTAGATGGAACTGCAAAAGGTGGAATAGTACTAGCTATTCGAAATGAAT
TACAATTACCGGTGAAGTTTGTAGGTTTAGGAGAAAAAATAAACGATTTGCAGCAGTTTGATGCATCTGCATTTGTTTAT
GGTCTATTTTCAGATATAGATATTGAAGCAAAAGAAGATTAA

Upstream 100 bases:

>100_bases
TTATACGGAGTTACGATGCAAGAGTCGGGAGTATCAAGATTAGTTTCTGTTCGTCTTGAAGATACAAAGGAATTAATTCG
TTCATAGGAGGAATGTACTG

Downstream 100 bases:

>100_bases
TCTACTATTTCCTTGACAATAAAACATGCTGTTCGCTATGATGTTCGTAAAGGAAAATCACTTAACAAGAGGTGTTTCCA
TTGTTAGATAAAACGACGCG

Product: signal recognition particle

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGFMDKLKQKFKQDNETKQVTEKYQEGMKKTRNSFSGKLNDLIARYRKVDEDFFEELEEVLITADVGVTTVMDLVEELKM
EVKRQNIKDSEQIKDVISEKLVEIYYGDEDESIEKLKIDGDGLKVILVVGVNGAGKTTSIGKLAHQLKQEGKNVVLAAGD
TFRAGAIEQLEVWGERADVPVIKQSEGSDPAAVIYDGVQAAKSRNADVLICDTAGRLQNKVNLMNELSKVKRVIEREIPD
APHEVLLVLDATTGQNALNQARTFSDATDVTGIVLTKLDGTAKGGIVLAIRNELQLPVKFVGLGEKINDLQQFDASAFVY
GLFSDIDIEAKED

Sequences:

>Translated_333_residues
MGFMDKLKQKFKQDNETKQVTEKYQEGMKKTRNSFSGKLNDLIARYRKVDEDFFEELEEVLITADVGVTTVMDLVEELKM
EVKRQNIKDSEQIKDVISEKLVEIYYGDEDESIEKLKIDGDGLKVILVVGVNGAGKTTSIGKLAHQLKQEGKNVVLAAGD
TFRAGAIEQLEVWGERADVPVIKQSEGSDPAAVIYDGVQAAKSRNADVLICDTAGRLQNKVNLMNELSKVKRVIEREIPD
APHEVLLVLDATTGQNALNQARTFSDATDVTGIVLTKLDGTAKGGIVLAIRNELQLPVKFVGLGEKINDLQQFDASAFVY
GLFSDIDIEAKED
>Mature_332_residues
GFMDKLKQKFKQDNETKQVTEKYQEGMKKTRNSFSGKLNDLIARYRKVDEDFFEELEEVLITADVGVTTVMDLVEELKME
VKRQNIKDSEQIKDVISEKLVEIYYGDEDESIEKLKIDGDGLKVILVVGVNGAGKTTSIGKLAHQLKQEGKNVVLAAGDT
FRAGAIEQLEVWGERADVPVIKQSEGSDPAAVIYDGVQAAKSRNADVLICDTAGRLQNKVNLMNELSKVKRVIEREIPDA
PHEVLLVLDATTGQNALNQARTFSDATDVTGIVLTKLDGTAKGGIVLAIRNELQLPVKFVGLGEKINDLQQFDASAFVYG
LFSDIDIEAKED

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=282, Percent_Identity=31.5602836879433, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI226371618, Length=206, Percent_Identity=36.4077669902913, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI23308697, Length=291, Percent_Identity=29.8969072164948, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI295424842, Length=291, Percent_Identity=29.8969072164948, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI89061728, Length=141, Percent_Identity=35.4609929078014, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1789874, Length=326, Percent_Identity=47.8527607361963, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1788963, Length=290, Percent_Identity=34.8275862068965, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=275, Percent_Identity=30.1818181818182, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI193206261, Length=297, Percent_Identity=31.3131313131313, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=206, Percent_Identity=37.378640776699, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320498, Length=229, Percent_Identity=29.6943231441048, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17647949, Length=282, Percent_Identity=30.4964539007092, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24641198, Length=306, Percent_Identity=29.0849673202614, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 36795; Mature: 36664

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFMDKLKQKFKQDNETKQVTEKYQEGMKKTRNSFSGKLNDLIARYRKVDEDFFEELEEV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
LITADVGVTTVMDLVEELKMEVKRQNIKDSEQIKDVISEKLVEIYYGDEDESIEKLKIDG
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEECC
DGLKVILVVGVNGAGKTTSIGKLAHQLKQEGKNVVLAAGDTFRAGAIEQLEVWGERADVP
CCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCCCCCCCC
VIKQSEGSDPAAVIYDGVQAAKSRNADVLICDTAGRLQNKVNLMNELSKVKRVIEREIPD
EEECCCCCCCCEEEEHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
APHEVLLVLDATTGQNALNQARTFSDATDVTGIVLTKLDGTAKGGIVLAIRNELQLPVKF
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEE
VGLGEKINDLQQFDASAFVYGLFSDIDIEAKED
EECCHHHHHHHHHCHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
GFMDKLKQKFKQDNETKQVTEKYQEGMKKTRNSFSGKLNDLIARYRKVDEDFFEELEEV
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
LITADVGVTTVMDLVEELKMEVKRQNIKDSEQIKDVISEKLVEIYYGDEDESIEKLKIDG
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEECC
DGLKVILVVGVNGAGKTTSIGKLAHQLKQEGKNVVLAAGDTFRAGAIEQLEVWGERADVP
CCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCCCCCCCC
VIKQSEGSDPAAVIYDGVQAAKSRNADVLICDTAGRLQNKVNLMNELSKVKRVIEREIPD
EEECCCCCCCCEEEEHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
APHEVLLVLDATTGQNALNQARTFSDATDVTGIVLTKLDGTAKGGIVLAIRNELQLPVKF
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEE
VGLGEKINDLQQFDASAFVYGLFSDIDIEAKED
EECCHHHHHHHHHCHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]