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The map label for this gene is rsmB [H]

Identifier: 23098962

GI number: 23098962

Start: 1550736

End: 1552082

Strand: Direct

Name: rsmB [H]

Synonym: OB1507

Alternate gene names: 23098962

Gene position: 1550736-1552082 (Clockwise)

Preceding gene: 23098961

Following gene: 23098963

Centisome position: 42.71

GC content: 34.15

Gene sequence:

>1347_bases
ATGAAGTATCAACTACGTAATACAATGCTCGATATATTAATTCGAATTGAAAAGGATCATGGTTTCAGTAATTTACTTCT
AAACCATGAATTAAAACAACGACAATTGAATGAAAAGGATGAACGTTTACTTACAGAAGTAGTGTATGGAAGTTTACAAC
ATCAGATGACATTGGATTATTACTTATCTAAGTTTGTTAAATCAAAGAAAAAGTTAGATATATGGGTCCAATCTTTACTT
AGAATGTCATTTTATCAAATGATTTATTTAGAGAAAGTACCTGACCATGCGGTAATTCATGAGTCCGTGGAAATTGCGAA
ACAGCGCGGGCATAAAGGAATATCATCTTTTGTAAATGGAGTATTACGTAGTTTACAACGTCAGGGAGTACCAGAATTAA
CTGAAATTAAAGACCCGATAGAACGTATAGCAATAGAGACGAGTCATCCAGAATGGTTAGTGAAACGATGGTCGGAAATG
TATGGTATGGAAACGACTGCAAATATGTGTAGAAATAATTTAGAACATCATCCACTTTCCATCCGTATTCAACCTTTACG
GACTTCTAGAGAAGATGTTATGGAAGAGTTGAAACAATCTGGTATTGAATGTCGTGCCTCTATATTTTCTAGCCAAGGTA
TTATTATTGAAAAAGGAAATATCTTTAGGACAAATCTTTTAAAAGATGGAAAAATTACTATACAAGACCAAAGTTCCATG
CTTGTTGGTGAAATGTTAGCTGTGGAACCGGAGATGAATGTATTAGATAGTTGTAGTGCTCCTGGAGGGAAAGTGACACA
TGTCGCTGAGAAGATGCTAGATAAAGGTACAATCCATGCTTTTGATTTACATGCTAAAAAAATAAAATTAATTGATGAAA
AAGCAACTACATTGCAATTGTCTTCTATCCTTGCGCAAAAAGGGGATGCGAGGAAGCTAGCAGATAAATATGAAAAAGAA
TCGTTTGATCGTATTGTTGTCGATGCACCTTGTTCTGGTTTAGGAGTAATTAATGGAAAGCCAGAAATTAAATATGAGAA
ATCTGAAGAAGATATTCAACGTTTAGCAAAAATTCAACAAGATATTTTAAATGAAGTGATTCCATTATTAAAAGAAAATG
GACTATTAATTTATAGTACATGTACGGTTGATACAGAGGAAAATAATCAAGTCGTTCGTCAGGTCCTAAAGAACCACCAA
GACATCTCCATTGATTTAAGCTTTCGCGATGAATTACCTGTAGAAATACAAGAGGCTCCTGGGTGGTCGGAAGAAGGATT
GCAATTATTTCCACAAGATTTTCACACAGATGGCTTCTTCTTAACGAGATTAAAAAAAATCCGATAA

Upstream 100 bases:

>100_bases
AGTGAAATTCAACCTGCTGGTAAAAAACGCATGTTGGTTGAAGATTATTTGAAAGGTTCTCAAGATCGAATAAAAATAGG
AATTAAATTAGGTGAATAAG

Downstream 100 bases:

>100_bases
TTTCGTTTTGTTATTGGTAAATTTGTGCAATACTTGATGTAAAGATAGTTAATTATGATTATAATGAAATAAAATTGGAG
ATAGGGGGGGAACAAGTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKYQLRNTMLDILIRIEKDHGFSNLLLNHELKQRQLNEKDERLLTEVVYGSLQHQMTLDYYLSKFVKSKKKLDIWVQSLL
RMSFYQMIYLEKVPDHAVIHESVEIAKQRGHKGISSFVNGVLRSLQRQGVPELTEIKDPIERIAIETSHPEWLVKRWSEM
YGMETTANMCRNNLEHHPLSIRIQPLRTSREDVMEELKQSGIECRASIFSSQGIIIEKGNIFRTNLLKDGKITIQDQSSM
LVGEMLAVEPEMNVLDSCSAPGGKVTHVAEKMLDKGTIHAFDLHAKKIKLIDEKATTLQLSSILAQKGDARKLADKYEKE
SFDRIVVDAPCSGLGVINGKPEIKYEKSEEDIQRLAKIQQDILNEVIPLLKENGLLIYSTCTVDTEENNQVVRQVLKNHQ
DISIDLSFRDELPVEIQEAPGWSEEGLQLFPQDFHTDGFFLTRLKKIR

Sequences:

>Translated_448_residues
MKYQLRNTMLDILIRIEKDHGFSNLLLNHELKQRQLNEKDERLLTEVVYGSLQHQMTLDYYLSKFVKSKKKLDIWVQSLL
RMSFYQMIYLEKVPDHAVIHESVEIAKQRGHKGISSFVNGVLRSLQRQGVPELTEIKDPIERIAIETSHPEWLVKRWSEM
YGMETTANMCRNNLEHHPLSIRIQPLRTSREDVMEELKQSGIECRASIFSSQGIIIEKGNIFRTNLLKDGKITIQDQSSM
LVGEMLAVEPEMNVLDSCSAPGGKVTHVAEKMLDKGTIHAFDLHAKKIKLIDEKATTLQLSSILAQKGDARKLADKYEKE
SFDRIVVDAPCSGLGVINGKPEIKYEKSEEDIQRLAKIQQDILNEVIPLLKENGLLIYSTCTVDTEENNQVVRQVLKNHQ
DISIDLSFRDELPVEIQEAPGWSEEGLQLFPQDFHTDGFFLTRLKKIR
>Mature_448_residues
MKYQLRNTMLDILIRIEKDHGFSNLLLNHELKQRQLNEKDERLLTEVVYGSLQHQMTLDYYLSKFVKSKKKLDIWVQSLL
RMSFYQMIYLEKVPDHAVIHESVEIAKQRGHKGISSFVNGVLRSLQRQGVPELTEIKDPIERIAIETSHPEWLVKRWSEM
YGMETTANMCRNNLEHHPLSIRIQPLRTSREDVMEELKQSGIECRASIFSSQGIIIEKGNIFRTNLLKDGKITIQDQSSM
LVGEMLAVEPEMNVLDSCSAPGGKVTHVAEKMLDKGTIHAFDLHAKKIKLIDEKATTLQLSSILAQKGDARKLADKYEKE
SFDRIVVDAPCSGLGVINGKPEIKYEKSEEDIQRLAKIQQDILNEVIPLLKENGLLIYSTCTVDTEENNQVVRQVLKNHQ
DISIDLSFRDELPVEIQEAPGWSEEGLQLFPQDFHTDGFFLTRLKKIR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=355, Percent_Identity=29.5774647887324, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI76150623, Length=355, Percent_Identity=29.5774647887324, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI32698918, Length=174, Percent_Identity=35.632183908046, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI8922322, Length=315, Percent_Identity=25.7142857142857, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI270288816, Length=315, Percent_Identity=25.7142857142857, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI270288818, Length=315, Percent_Identity=25.7142857142857, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI23199998, Length=315, Percent_Identity=25.7142857142857, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301336155, Length=212, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI39995082, Length=212, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI11545785, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367212, Length=436, Percent_Identity=30.2752293577982, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081985, Length=277, Percent_Identity=30.3249097472924, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17536757, Length=292, Percent_Identity=29.4520547945205, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71998419, Length=247, Percent_Identity=29.1497975708502, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI115534021, Length=245, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25143471, Length=179, Percent_Identity=29.608938547486, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=290, Percent_Identity=27.5862068965517, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=267, Percent_Identity=25.8426966292135, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324306, Length=294, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI22024126, Length=284, Percent_Identity=30.6338028169014, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24668781, Length=238, Percent_Identity=31.0924369747899, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356513, Length=238, Percent_Identity=31.0924369747899, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356579, Length=230, Percent_Identity=26.9565217391304, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355201, Length=235, Percent_Identity=25.9574468085106, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19920494, Length=180, Percent_Identity=31.6666666666667, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 51491; Mature: 51491

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQLRNTMLDILIRIEKDHGFSNLLLNHELKQRQLNEKDERLLTEVVYGSLQHQMTLDY
CCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLSKFVKSKKKLDIWVQSLLRMSFYQMIYLEKVPDHAVIHESVEIAKQRGHKGISSFVNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
VLRSLQRQGVPELTEIKDPIERIAIETSHPEWLVKRWSEMYGMETTANMCRNNLEHHPLS
HHHHHHHCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEE
IRIQPLRTSREDVMEELKQSGIECRASIFSSQGIIIEKGNIFRTNLLKDGKITIQDQSSM
EEEEECCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEECCCCH
LVGEMLAVEPEMNVLDSCSAPGGKVTHVAEKMLDKGTIHAFDLHAKKIKLIDEKATTLQL
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHECCHHHHHHH
SSILAQKGDARKLADKYEKESFDRIVVDAPCSGLGVINGKPEIKYEKSEEDIQRLAKIQQ
HHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCEECCCHHHHHHHHHHHH
DILNEVIPLLKENGLLIYSTCTVDTEENNQVVRQVLKNHQDISIDLSFRDELPVEIQEAP
HHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEECCC
GWSEEGLQLFPQDFHTDGFFLTRLKKIR
CCCCCCHHHCCHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKYQLRNTMLDILIRIEKDHGFSNLLLNHELKQRQLNEKDERLLTEVVYGSLQHQMTLDY
CCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLSKFVKSKKKLDIWVQSLLRMSFYQMIYLEKVPDHAVIHESVEIAKQRGHKGISSFVNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
VLRSLQRQGVPELTEIKDPIERIAIETSHPEWLVKRWSEMYGMETTANMCRNNLEHHPLS
HHHHHHHCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEE
IRIQPLRTSREDVMEELKQSGIECRASIFSSQGIIIEKGNIFRTNLLKDGKITIQDQSSM
EEEEECCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEECCCCH
LVGEMLAVEPEMNVLDSCSAPGGKVTHVAEKMLDKGTIHAFDLHAKKIKLIDEKATTLQL
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHECCHHHHHHH
SSILAQKGDARKLADKYEKESFDRIVVDAPCSGLGVINGKPEIKYEKSEEDIQRLAKIQQ
HHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCEECCCHHHHHHHHHHHH
DILNEVIPLLKENGLLIYSTCTVDTEENNQVVRQVLKNHQDISIDLSFRDELPVEIQEAP
HHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEECCC
GWSEEGLQLFPQDFHTDGFFLTRLKKIR
CCCCCCHHHCCHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]