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The map label for this gene is pyrDII [H]

Identifier: 23098947

GI number: 23098947

Start: 1534339

End: 1535094

Strand: Direct

Name: pyrDII [H]

Synonym: OB1492

Alternate gene names: 23098947

Gene position: 1534339-1535094 (Clockwise)

Preceding gene: 23098946

Following gene: 23098948

Centisome position: 42.26

GC content: 41.14

Gene sequence:

>756_bases
ATGAGAAAACGCGAGACAATGTCTGTTCTATCGGTAACACAAATTGCTACAGACACCTTTGAGATGATAGCGGAAAATAG
TAGAATTAGTGAACAGGCAAAACCAGGACAATTCGTACACATTTACATTCCTGGACATACGTTACGACGTCCGATCTCTA
TTGCAGCAGTGGATCCTTCCACTGCTAGTGTTTCACTTGTATTTAAAGCAATTGGAGATGGGACGAAACAATTATCAAAC
TATCTACCGGGAATGCAAATCGATGTGTTAGGTCCGAATGGGAATGGTTTTTCTATAGATATTTCTGAAGATGAACGGGT
GCTGCTAATTGGAGGAGGAGTAGGTGTTCCACCAATGTATCACTTGGCAAAACGGCTGTCAGAAGAAACATCGATAGATA
TTGTCTCAGTGCTTGGGTTTCAGACAAAAAATGCAGTATTTTACGAAGAAGAGTTTAACCGTATTGGTGAAACGTATATT
GTTACCGATGATGGTTCTTATGGGACCCACGGTGTCGTTACAGATATTGTAGGACAATTTACAGATCGTACACAATACTT
TAGCTGTGGTCCATTGCCAATGTTAAGAGCGGTGAAAAGTAAACTTAGTCATATCCCAGGAAAGGTTTCTCTAGAGGAAA
GAATGGGATGTGGCGTAGGTGCATGCATGGCCTGTGTATTGCCTACCGTGGATAATCATTATAAAAAAATCTGTAGTGAA
GGACCAGTTTTTGTTGCTGAGGAGGTGGTCCTATGA

Upstream 100 bases:

>100_bases
GTTTGACAAATATGGATACCGTAAACGCCATATTACGAGTTATTGATGCAACATCGTTTAGTGCGAAACCGATTGGAATA
GATAAGAAGGTGGTCATGTC

Downstream 100 bases:

>100_bases
ATCTGTCAGTAAAATTACCAGGATTAAACTTAAAAAATCCGATCATGCCGGCATCTGGTTGTTTTGGGTTTGGAAAAGAA
TACAGTGAGTATTATGATTT

Product: dihydroorotate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRKRETMSVLSVTQIATDTFEMIAENSRISEQAKPGQFVHIYIPGHTLRRPISIAAVDPSTASVSLVFKAIGDGTKQLSN
YLPGMQIDVLGPNGNGFSIDISEDERVLLIGGGVGVPPMYHLAKRLSEETSIDIVSVLGFQTKNAVFYEEEFNRIGETYI
VTDDGSYGTHGVVTDIVGQFTDRTQYFSCGPLPMLRAVKSKLSHIPGKVSLEERMGCGVGACMACVLPTVDNHYKKICSE
GPVFVAEEVVL

Sequences:

>Translated_251_residues
MRKRETMSVLSVTQIATDTFEMIAENSRISEQAKPGQFVHIYIPGHTLRRPISIAAVDPSTASVSLVFKAIGDGTKQLSN
YLPGMQIDVLGPNGNGFSIDISEDERVLLIGGGVGVPPMYHLAKRLSEETSIDIVSVLGFQTKNAVFYEEEFNRIGETYI
VTDDGSYGTHGVVTDIVGQFTDRTQYFSCGPLPMLRAVKSKLSHIPGKVSLEERMGCGVGACMACVLPTVDNHYKKICSE
GPVFVAEEVVL
>Mature_251_residues
MRKRETMSVLSVTQIATDTFEMIAENSRISEQAKPGQFVHIYIPGHTLRRPISIAAVDPSTASVSLVFKAIGDGTKQLSN
YLPGMQIDVLGPNGNGFSIDISEDERVLLIGGGVGVPPMYHLAKRLSEETSIDIVSVLGFQTKNAVFYEEEFNRIGETYI
VTDDGSYGTHGVVTDIVGQFTDRTQYFSCGPLPMLRAVKSKLSHIPGKVSLEERMGCGVGACMACVLPTVDNHYKKICSE
GPVFVAEEVVL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 27278; Mature: 27278

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRETMSVLSVTQIATDTFEMIAENSRISEQAKPGQFVHIYIPGHTLRRPISIAAVDPS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEECCHHHCCCEEEEEECCC
TASVSLVFKAIGDGTKQLSNYLPGMQIDVLGPNGNGFSIDISEDERVLLIGGGVGVPPMY
CCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCEEEEEECCCCCCHHH
HLAKRLSEETSIDIVSVLGFQTKNAVFYEEEFNRIGETYIVTDDGSYGTHGVVTDIVGQF
HHHHHHCCCCCEEEEHHHCCCCCCEEEEHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHH
TDRTQYFSCGPLPMLRAVKSKLSHIPGKVSLEERMGCGVGACMACVLPTVDNHYKKICSE
CCCCCCEECCCHHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHCCHHHHHHHHHCC
GPVFVAEEVVL
CCEEEEEEECC
>Mature Secondary Structure
MRKRETMSVLSVTQIATDTFEMIAENSRISEQAKPGQFVHIYIPGHTLRRPISIAAVDPS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEECCHHHCCCEEEEEECCC
TASVSLVFKAIGDGTKQLSNYLPGMQIDVLGPNGNGFSIDISEDERVLLIGGGVGVPPMY
CCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCEEEEEECCCCCCHHH
HLAKRLSEETSIDIVSVLGFQTKNAVFYEEEFNRIGETYIVTDDGSYGTHGVVTDIVGQF
HHHHHHCCCCCEEEEHHHCCCCCCEEEEHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHH
TDRTQYFSCGPLPMLRAVKSKLSHIPGKVSLEERMGCGVGACMACVLPTVDNHYKKICSE
CCCCCCEECCCHHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHCCHHHHHHHHHCC
GPVFVAEEVVL
CCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7516791 [H]