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The map label for this gene is luxS

Identifier: 23098562

GI number: 23098562

Start: 1160576

End: 1161037

Strand: Direct

Name: luxS

Synonym: OB1107

Alternate gene names: 23098562

Gene position: 1160576-1161037 (Clockwise)

Preceding gene: 23098561

Following gene: 23098563

Centisome position: 31.97

GC content: 34.63

Gene sequence:

>462_bases
ATGACTAAAAAAATGAATGTAGAAAGTTTTAATCTTGATCATACAAAAGTAAAAGCTCCCTATGTAAGATTAGTTGGGGT
TACTGAAGGTGCAAATGGTGATAAAGTGCACAAGTATGACATTCGTATTAAACAACCAAATAAAGCACACATGGAAATGC
CAGGTCTCCATTCGTTAGAACATCTAATGGCAGAAAATATTCGAAACCATTCTGATGCAGTTCTTGATATTGGACCGATG
GGATGTCAGACAGGATTTTATCTATCATTAATTAATCATGATGATTATGATGATGTTCTTACAATGATTGAAAAAACGCT
AGAAGACGTTTTACAAGCTACTGAAGTACCAGCTTGTAATGAAGTTCAGTGTGGATGGGCTGCAAATCATAGCCTTTTAG
GTGCTCAGGAAATTGCAAAAGAAATGTTAAATGAAAAAGCAAGCTGGTCAGAAGTATTTTAA

Upstream 100 bases:

>100_bases
TGCTTTTGAAAAGTACAATTTTCATGTATCATTTAAACAGATGAATGATTTTGTGTGGATAATCAGCGCAAAAAAATTAG
CATGAAGGAGAGATATACCA

Downstream 100 bases:

>100_bases
AAAAATAAAATCCTCATTGTACTCTTTCTCTCCAAGGTAGGAGTGACAATTCATTGGCAATTTATGAATCGATACAACAA
TTGATTGGCAATACACCTTT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTKKMNVESFNLDHTKVKAPYVRLVGVTEGANGDKVHKYDIRIKQPNKAHMEMPGLHSLEHLMAENIRNHSDAVLDIGPM
GCQTGFYLSLINHDDYDDVLTMIEKTLEDVLQATEVPACNEVQCGWAANHSLLGAQEIAKEMLNEKASWSEVF

Sequences:

>Translated_153_residues
MTKKMNVESFNLDHTKVKAPYVRLVGVTEGANGDKVHKYDIRIKQPNKAHMEMPGLHSLEHLMAENIRNHSDAVLDIGPM
GCQTGFYLSLINHDDYDDVLTMIEKTLEDVLQATEVPACNEVQCGWAANHSLLGAQEIAKEMLNEKASWSEVF
>Mature_152_residues
TKKMNVESFNLDHTKVKAPYVRLVGVTEGANGDKVHKYDIRIKQPNKAHMEMPGLHSLEHLMAENIRNHSDAVLDIGPMG
CQTGFYLSLINHDDYDDVLTMIEKTLEDVLQATEVPACNEVQCGWAANHSLLGAQEIAKEMLNEKASWSEVF

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=144, Percent_Identity=40.9722222222222, Blast_Score=113, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_OCEIH (Q8CUK0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692028.1
- ProteinModelPortal:   Q8CUK0
- SMR:   Q8CUK0
- GeneID:   1017138
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1107
- NMPDR:   fig|221109.1.peg.1108
- HOGENOM:   HBG347473
- OMA:   STIPELN
- ProtClustDB:   PRK02260
- BioCyc:   OIHE221109:OB1107-MONOMER
- BRENDA:   4.4.1.21
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17166; Mature: 17035

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKMNVESFNLDHTKVKAPYVRLVGVTEGANGDKVHKYDIRIKQPNKAHMEMPGLHSLE
CCCCCCCCCCCCCCCEECCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHH
HLMAENIRNHSDAVLDIGPMGCQTGFYLSLINHDDYDDVLTMIEKTLEDVLQATEVPACN
HHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
EVQCGWAANHSLLGAQEIAKEMLNEKASWSEVF
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TKKMNVESFNLDHTKVKAPYVRLVGVTEGANGDKVHKYDIRIKQPNKAHMEMPGLHSLE
CCCCCCCCCCCCCCEECCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHH
HLMAENIRNHSDAVLDIGPMGCQTGFYLSLINHDDYDDVLTMIEKTLEDVLQATEVPACN
HHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
EVQCGWAANHSLLGAQEIAKEMLNEKASWSEVF
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376