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The map label for this gene is murG

Identifier: 23098548

GI number: 23098548

Start: 1144264

End: 1145337

Strand: Direct

Name: murG

Synonym: OB1093

Alternate gene names: 23098548

Gene position: 1144264-1145337 (Clockwise)

Preceding gene: 23098546

Following gene: 23098553

Centisome position: 31.52

GC content: 34.92

Gene sequence:

>1074_bases
ATGAAAAATAATAAACGAATTTTATTTACAGGTGGCGGCACAGCAGGACATGTTATCGTTAATTTAGCACTTATACCGTA
CTATCAAGAGCGAGGTTGGGAAATTGATTATATTGGCTCTTATAATGGAATAGAAAGAGATTTAATTTCGCCATTAGATG
GGGTAACTTATCACTCTGTATCTACTGGGAAATTACGAAGATACATGTCCAAAGAAAATTTAAAGGATCCATTCAAAGTA
CTCAAGGGTACGATGCAAGCATACCGCATAATTGGGAAACGTAAACCATCGATCGTATTTTCAAAAGGTGGATTTGTGTC
TGTACCAGTTGTCGCAGCTGCAAAACTTAGAGGCGTGCCATCGATTATTCATGAATCCGATTATACACCAGGATTGGCTA
ATAAATTATCTATACCTTTTACGAAAAGAGTGTTGGCTACTTTTCCAGAAACCATGAAATATTTACCGGAGAACAAGGCA
TCTTATGTTGGAGCGGTAATTCGTGATGAATTATTTACTGGTAAGCGTGATATTGGTTTAAAGATAAGTGGTTTAAAGGG
GAACAAACCAGTTTTACTTGTAATGGGAGGAAGTGGAGGATCTGAAAAAATTAATCAGACCATTCGTCAATCCTTAACTA
AACTTCTAGACGAATTTGAAATTATTCATATATGTGGCAAAGGAAAGGTTGATGATTCCATACAATTGGATGGTTATGTT
CAGTTTGAATATATTAACCATGAACTAAAAGATATATTCGCTGCAACCGATCTAGTCATTTCTCGCGCCGGTTCTAATGC
AATCTTTGAATTTTTAGCATTACGTTTGCCTATGTTACTAATACCATTATCAAAAGAAGCTAGCCGAGGCGATCAAATTA
TAAATGCGAACTCTTTTAAGAAAAAGAACTATGCTAGAGTATTGCAGGAAGAAGAACTTACAGAACAATCATTAGAAAGT
CATCTTTTAGAATTAAGTAAAGCAGCGCCAATTATAAGAGATGAAATGAAAAAATATAAAAGTGAGCAATCACTACAGTC
AGTGACTGAAATAATCGATAATGTCATGAAATAA

Upstream 100 bases:

>100_bases
AATCTTCTTCCTTTTTTAATTTCCTTATTAATATAACGTAATTATATAGTGCATTGACTATTATACGCTGATATAATGTG
TTGGGAAAGGAATGAGTTCC

Downstream 100 bases:

>100_bases
GGAAGAAGAACAAATTTCCTTCAATTATTTATGTATAATGTAAAAATTCTCCCTCTAATGTAAATATGATTAGAGGGAGT
CTGGTTATAATATTTTCTAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKNNKRILFTGGGTAGHVIVNLALIPYYQERGWEIDYIGSYNGIERDLISPLDGVTYHSVSTGKLRRYMSKENLKDPFKV
LKGTMQAYRIIGKRKPSIVFSKGGFVSVPVVAAAKLRGVPSIIHESDYTPGLANKLSIPFTKRVLATFPETMKYLPENKA
SYVGAVIRDELFTGKRDIGLKISGLKGNKPVLLVMGGSGGSEKINQTIRQSLTKLLDEFEIIHICGKGKVDDSIQLDGYV
QFEYINHELKDIFAATDLVISRAGSNAIFEFLALRLPMLLIPLSKEASRGDQIINANSFKKKNYARVLQEEELTEQSLES
HLLELSKAAPIIRDEMKKYKSEQSLQSVTEIIDNVMK

Sequences:

>Translated_357_residues
MKNNKRILFTGGGTAGHVIVNLALIPYYQERGWEIDYIGSYNGIERDLISPLDGVTYHSVSTGKLRRYMSKENLKDPFKV
LKGTMQAYRIIGKRKPSIVFSKGGFVSVPVVAAAKLRGVPSIIHESDYTPGLANKLSIPFTKRVLATFPETMKYLPENKA
SYVGAVIRDELFTGKRDIGLKISGLKGNKPVLLVMGGSGGSEKINQTIRQSLTKLLDEFEIIHICGKGKVDDSIQLDGYV
QFEYINHELKDIFAATDLVISRAGSNAIFEFLALRLPMLLIPLSKEASRGDQIINANSFKKKNYARVLQEEELTEQSLES
HLLELSKAAPIIRDEMKKYKSEQSLQSVTEIIDNVMK
>Mature_357_residues
MKNNKRILFTGGGTAGHVIVNLALIPYYQERGWEIDYIGSYNGIERDLISPLDGVTYHSVSTGKLRRYMSKENLKDPFKV
LKGTMQAYRIIGKRKPSIVFSKGGFVSVPVVAAAKLRGVPSIIHESDYTPGLANKLSIPFTKRVLATFPETMKYLPENKA
SYVGAVIRDELFTGKRDIGLKISGLKGNKPVLLVMGGSGGSEKINQTIRQSLTKLLDEFEIIHICGKGKVDDSIQLDGYV
QFEYINHELKDIFAATDLVISRAGSNAIFEFLALRLPMLLIPLSKEASRGDQIINANSFKKKNYARVLQEEELTEQSLES
HLLELSKAAPIIRDEMKKYKSEQSLQSVTEIIDNVMK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=28.3333333333333, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_OCEIH (Q8CUL4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692014.1
- ProteinModelPortal:   Q8CUL4
- SMR:   Q8CUL4
- GeneID:   1017069
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1093
- NMPDR:   fig|221109.1.peg.1094
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- BioCyc:   OIHE221109:OB1093-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39817; Mature: 39817

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNKRILFTGGGTAGHVIVNLALIPYYQERGWEIDYIGSYNGIERDLISPLDGVTYHSV
CCCCCEEEEECCCCCCEEEEEEHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCEEECC
STGKLRRYMSKENLKDPFKVLKGTMQAYRIIGKRKPSIVFSKGGFVSVPVVAAAKLRGVP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHHHCCCH
SIIHESDYTPGLANKLSIPFTKRVLATFPETMKYLPENKASYVGAVIRDELFTGKRDIGL
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCE
KISGLKGNKPVLLVMGGSGGSEKINQTIRQSLTKLLDEFEIIHICGKGKVDDSIQLDGYV
EEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEECCEE
QFEYINHELKDIFAATDLVISRAGSNAIFEFLALRLPMLLIPLSKEASRGDQIINANSFK
EEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEECCCCCC
KKNYARVLQEEELTEQSLESHLLELSKAAPIIRDEMKKYKSEQSLQSVTEIIDNVMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNNKRILFTGGGTAGHVIVNLALIPYYQERGWEIDYIGSYNGIERDLISPLDGVTYHSV
CCCCCEEEEECCCCCCEEEEEEHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCEEECC
STGKLRRYMSKENLKDPFKVLKGTMQAYRIIGKRKPSIVFSKGGFVSVPVVAAAKLRGVP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHHHCCCH
SIIHESDYTPGLANKLSIPFTKRVLATFPETMKYLPENKASYVGAVIRDELFTGKRDIGL
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCE
KISGLKGNKPVLLVMGGSGGSEKINQTIRQSLTKLLDEFEIIHICGKGKVDDSIQLDGYV
EEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEECCEE
QFEYINHELKDIFAATDLVISRAGSNAIFEFLALRLPMLLIPLSKEASRGDQIINANSFK
EEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCEECCCCCC
KKNYARVLQEEELTEQSLESHLLELSKAAPIIRDEMKKYKSEQSLQSVTEIIDNVMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376