Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 23098324

GI number: 23098324

Start: 922800

End: 923519

Strand: Direct

Name: plsC [H]

Synonym: OB0869

Alternate gene names: 23098324

Gene position: 922800-923519 (Clockwise)

Preceding gene: 23098322

Following gene: 23098325

Centisome position: 25.42

GC content: 35.14

Gene sequence:

>720_bases
ATGATGCGAACAATTGGATTCTTTGTTTATGCGTCCTTACTGATTATAGGGACTATCTTTAAATTACAAAAAGTGAAAAA
CTGGGCTGATACTGGACTTGCTGTAGAAAAACAGGACGAGATATTTGCAACGCCAAAAATAGTATCTCAAAAAGCAATTG
CCAAAACAGGAACAGATGTGAATGTAGAAGGGTTACAAAAAGTACCATCAGGACCAGTTTTGTTTGTAGCAAATCATCAA
GGAATATTTGATATATTGGCTTTCTTAGGATATCTTGAGCGTCCAGTTGGCTTTATTGCAAAAAAAGAAATCAAAAAGAT
TCCGATAATCTCTACGTGGATGGAATTTGTCCATTGCGTGTTTATCGACCGGACAGATCGCAGGCAATCGATGAAGGCGA
TCCAACAAGGGATAAAAAATTTAGAAAATGGAAATTCAATGCTGATTTTTCCTGAAGGTACTAGAAGTAAAGGAAGAGAA
GTAAGTAGTTTTAAAGCCGGCAGCTTTCGTTTAGCAACGAAATCTAACGTTCCTATTGTTCCTGTAAGTATAGATGGAAC
GTATCAAATGTTAGAAGAAGATGGTGGTAGAATTAAAAAATCTTCCATTCAAATTGTTATTGATGATCCAATTATGCCTG
CACAATACGAGAAAATGAAAAGTGCAGAAATTGCTAGTAATGTAGAGCGTATAATTAGAAAAAGGTTACATGATAAATAA

Upstream 100 bases:

>100_bases
CTTCAATCAATTTATTCGTTTTTCGACAAATTTCTTCATTATAAATAGTAATCATAGTATAATAACCTTTGTGTGCACGT
GCACAGAGGGAGTGTTAAGT

Downstream 100 bases:

>100_bases
ATGAATAGCATTTGGATAAACACTTTTGAACGGAAGGCATTCCTTTTATTCTGAGTGTTTTTTTGTATGGATTAGAAACA
AATAAGGGTAAAATAAAAAA

Product: 1-acyl-sn-glycerol-3-phosphate acetyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MMRTIGFFVYASLLIIGTIFKLQKVKNWADTGLAVEKQDEIFATPKIVSQKAIAKTGTDVNVEGLQKVPSGPVLFVANHQ
GIFDILAFLGYLERPVGFIAKKEIKKIPIISTWMEFVHCVFIDRTDRRQSMKAIQQGIKNLENGNSMLIFPEGTRSKGRE
VSSFKAGSFRLATKSNVPIVPVSIDGTYQMLEEDGGRIKKSSIQIVIDDPIMPAQYEKMKSAEIASNVERIIRKRLHDK

Sequences:

>Translated_239_residues
MMRTIGFFVYASLLIIGTIFKLQKVKNWADTGLAVEKQDEIFATPKIVSQKAIAKTGTDVNVEGLQKVPSGPVLFVANHQ
GIFDILAFLGYLERPVGFIAKKEIKKIPIISTWMEFVHCVFIDRTDRRQSMKAIQQGIKNLENGNSMLIFPEGTRSKGRE
VSSFKAGSFRLATKSNVPIVPVSIDGTYQMLEEDGGRIKKSSIQIVIDDPIMPAQYEKMKSAEIASNVERIIRKRLHDK
>Mature_239_residues
MMRTIGFFVYASLLIIGTIFKLQKVKNWADTGLAVEKQDEIFATPKIVSQKAIAKTGTDVNVEGLQKVPSGPVLFVANHQ
GIFDILAFLGYLERPVGFIAKKEIKKIPIISTWMEFVHCVFIDRTDRRQSMKAIQQGIKNLENGNSMLIFPEGTRSKGRE
VSSFKAGSFRLATKSNVPIVPVSIDGTYQMLEEDGGRIKKSSIQIVIDDPIMPAQYEKMKSAEIASNVERIIRKRLHDK

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789395, Length=167, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564032, Length=202, Percent_Identity=26.2376237623762, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=176, Percent_Identity=32.3863636363636, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281364648, Length=203, Percent_Identity=28.0788177339901, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582856, Length=203, Percent_Identity=28.0788177339901, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582854, Length=203, Percent_Identity=28.0788177339901, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26789; Mature: 26789

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTIGFFVYASLLIIGTIFKLQKVKNWADTGLAVEKQDEIFATPKIVSQKAIAKTGTDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECHHHHHHHHHHHCCCCC
NVEGLQKVPSGPVLFVANHQGIFDILAFLGYLERPVGFIAKKEIKKIPIISTWMEFVHCV
CHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FIDRTDRRQSMKAIQQGIKNLENGNSMLIFPEGTRSKGREVSSFKAGSFRLATKSNVPIV
HCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEE
PVSIDGTYQMLEEDGGRIKKSSIQIVIDDPIMPAQYEKMKSAEIASNVERIIRKRLHDK
EEECCCHHHHHHHCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRTIGFFVYASLLIIGTIFKLQKVKNWADTGLAVEKQDEIFATPKIVSQKAIAKTGTDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECHHHHHHHHHHHCCCCC
NVEGLQKVPSGPVLFVANHQGIFDILAFLGYLERPVGFIAKKEIKKIPIISTWMEFVHCV
CHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FIDRTDRRQSMKAIQQGIKNLENGNSMLIFPEGTRSKGREVSSFKAGSFRLATKSNVPIV
HCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEE
PVSIDGTYQMLEEDGGRIKKSSIQIVIDDPIMPAQYEKMKSAEIASNVERIIRKRLHDK
EEECCCHHHHHHHCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]