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The map label for this gene is gmuD [H]

Identifier: 23098234

GI number: 23098234

Start: 834759

End: 836198

Strand: Direct

Name: gmuD [H]

Synonym: OB0779

Alternate gene names: 23098234

Gene position: 834759-836198 (Clockwise)

Preceding gene: 23098233

Following gene: 23098235

Centisome position: 22.99

GC content: 35.56

Gene sequence:

>1440_bases
ATGGAAAATGTAACAATAAAGGTGCCGAATAATTTTATGTTAGGGGCAGCTGTTTCAGCGTGGCAGACCGAGGGATGGAT
TGGAAAAAGGGACTCTCAGGACTCCTATTTGGACATCTGGTATAAAAACAATAAACATGTTTGGCATAATGGTTACGGTC
CTGCGGGAGCAACAAATTTCTATCAGCGTTATGAGGAAGACATAGATTATATGAAAGAAATAGGATTAACTCATTTTCGA
ACATCGATTAACTGGTCACGTTTTTTAATAGATTATGAGAATGCTATTGTTGATGAGGAATATGCAGCTTATGTGGATGA
TGTTATTGAGAAATTAATACAAAACGGTGTAGAGCCAATGATCTGTCTGGAGCATTATGAGGTTCCGGCTGTTTTATTTG
AAAAATATGGAGGCTGGGAATCAAAGCATGTAGTGGAATTATTTGTTCAATATGCTAATAAAGTTTTTGAGAGGTATGGA
GACAAGGTAAAGCATTGGTTTACCTTTAATGAACCAATCGTAGTACAGACTCGCGTATATTTAGATGCTATTCGCTGGCC
GTTTGAACAAAGCACAAAAAAATGGATGCAGTGGAACTACAACAAAGTGTTGGCGACAGCCAAGGTAGTAAATTTATTCA
AAGACTTGCAACTTAAAGATAAAAATGGAGCAAAAATTGGCGTTATCTTAAATCCAGAAGTCACCTATGCACGTTCTACT
GCTACACATGATCAACAAGCGGCAAAGATGTATGATTTGTTTTTTAATCGTATATTTCTGGATCCCTCGATTAAAGGAGA
ATACCCGAAAGAATTATTTGATGTAATGAAGAAACATGGGATTACATTTGATTTTACGGAAGAAGAGTTAAATTTGATTA
AGGATAATACGGTAGATTATGTCGGTTTAAATCTATATTTTCCACACCGAGTTAAAGCACGTACAGCTGGGTGGAATGAA
CAAACCCCATTTCATCCTGCGTATTATTATGAGATATTTGAACTCCCAGGTAAGAAAATGAATCCCTACCGTGGATGGGA
AATATATCCACAAATTATGTATGATATGGGAATTCGAATGAAAGAGGAATATGACAATATTGAATGGTTCATTGCGGAAA
ACGGGATGGGAGTAGAAAACGAGAAGAGATTTAAGGATGCGTCGAATATGATTCAGGATGATTATCGAATTGAATTTATT
CGTGAGCATTTAAAATGGCTATTAAAGGCAGTAGAAGAAGGTGTTAATTGTAAAGGGTATATGCTTTGGGCTTTTACCGA
TAATGTATCACCTATGAATGCTTTTAAAAATAGATATGGATTAGTAGAAATTGATTTGGAGGATAATCGTAATCGTCATC
TGAAAAAATCTGCTTACTGGTATAAACAGCTAATAGAATCAAGAAAATTTGAAGCGGAAAATGATGAGAATTACAAATAG

Upstream 100 bases:

>100_bases
AATATTTTGTCAGTGTGTTCAAGAAGTTTTCTGGATTGACTCCAACGAATTACCGAAAATTAACTGCAATTGAATAGAAG
CTATAAAGGAGGAAGTTTGA

Downstream 100 bases:

>100_bases
AAAATAATTTTCTAGCCAGAGATTTATGGATAAATCGTTAAGGGGTGGATAGATGGACAGGTATTTAGCATTCGATATTG
GTGGAACTTTTTTGAAATAT

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MENVTIKVPNNFMLGAAVSAWQTEGWIGKRDSQDSYLDIWYKNNKHVWHNGYGPAGATNFYQRYEEDIDYMKEIGLTHFR
TSINWSRFLIDYENAIVDEEYAAYVDDVIEKLIQNGVEPMICLEHYEVPAVLFEKYGGWESKHVVELFVQYANKVFERYG
DKVKHWFTFNEPIVVQTRVYLDAIRWPFEQSTKKWMQWNYNKVLATAKVVNLFKDLQLKDKNGAKIGVILNPEVTYARST
ATHDQQAAKMYDLFFNRIFLDPSIKGEYPKELFDVMKKHGITFDFTEEELNLIKDNTVDYVGLNLYFPHRVKARTAGWNE
QTPFHPAYYYEIFELPGKKMNPYRGWEIYPQIMYDMGIRMKEEYDNIEWFIAENGMGVENEKRFKDASNMIQDDYRIEFI
REHLKWLLKAVEEGVNCKGYMLWAFTDNVSPMNAFKNRYGLVEIDLEDNRNRHLKKSAYWYKQLIESRKFEAENDENYK

Sequences:

>Translated_479_residues
MENVTIKVPNNFMLGAAVSAWQTEGWIGKRDSQDSYLDIWYKNNKHVWHNGYGPAGATNFYQRYEEDIDYMKEIGLTHFR
TSINWSRFLIDYENAIVDEEYAAYVDDVIEKLIQNGVEPMICLEHYEVPAVLFEKYGGWESKHVVELFVQYANKVFERYG
DKVKHWFTFNEPIVVQTRVYLDAIRWPFEQSTKKWMQWNYNKVLATAKVVNLFKDLQLKDKNGAKIGVILNPEVTYARST
ATHDQQAAKMYDLFFNRIFLDPSIKGEYPKELFDVMKKHGITFDFTEEELNLIKDNTVDYVGLNLYFPHRVKARTAGWNE
QTPFHPAYYYEIFELPGKKMNPYRGWEIYPQIMYDMGIRMKEEYDNIEWFIAENGMGVENEKRFKDASNMIQDDYRIEFI
REHLKWLLKAVEEGVNCKGYMLWAFTDNVSPMNAFKNRYGLVEIDLEDNRNRHLKKSAYWYKQLIESRKFEAENDENYK
>Mature_479_residues
MENVTIKVPNNFMLGAAVSAWQTEGWIGKRDSQDSYLDIWYKNNKHVWHNGYGPAGATNFYQRYEEDIDYMKEIGLTHFR
TSINWSRFLIDYENAIVDEEYAAYVDDVIEKLIQNGVEPMICLEHYEVPAVLFEKYGGWESKHVVELFVQYANKVFERYG
DKVKHWFTFNEPIVVQTRVYLDAIRWPFEQSTKKWMQWNYNKVLATAKVVNLFKDLQLKDKNGAKIGVILNPEVTYARST
ATHDQQAAKMYDLFFNRIFLDPSIKGEYPKELFDVMKKHGITFDFTEEELNLIKDNTVDYVGLNLYFPHRVKARTAGWNE
QTPFHPAYYYEIFELPGKKMNPYRGWEIYPQIMYDMGIRMKEEYDNIEWFIAENGMGVENEKRFKDASNMIQDDYRIEFI
REHLKWLLKAVEEGVNCKGYMLWAFTDNVSPMNAFKNRYGLVEIDLEDNRNRHLKKSAYWYKQLIESRKFEAENDENYK

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=484, Percent_Identity=28.099173553719, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI110681710, Length=484, Percent_Identity=25.6198347107438, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI32481206, Length=486, Percent_Identity=26.1316872427983, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24497614, Length=484, Percent_Identity=25.8264462809917, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI28376633, Length=477, Percent_Identity=24.9475890985325, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI2367174, Length=494, Percent_Identity=30.1619433198381, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1789070, Length=487, Percent_Identity=29.5687885010267, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI2367270, Length=490, Percent_Identity=27.9591836734694, Blast_Score=179, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17552856, Length=480, Percent_Identity=27.9166666666667, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17539390, Length=483, Percent_Identity=27.7432712215321, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356577, Length=488, Percent_Identity=25.8196721311475, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 57098; Mature: 57098

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVTIKVPNNFMLGAAVSAWQTEGWIGKRDSQDSYLDIWYKNNKHVWHNGYGPAGATNF
CCCEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHH
YQRYEEDIDYMKEIGLTHFRTSINWSRFLIDYENAIVDEEYAAYVDDVIEKLIQNGVEPM
HHHHHHHHHHHHHCCHHHHCCCCCHHHEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCE
ICLEHYEVPAVLFEKYGGWESKHVVELFVQYANKVFERYGDKVKHWFTFNEPIVVQTRVY
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHHH
LDAIRWPFEQSTKKWMQWNYNKVLATAKVVNLFKDLQLKDKNGAKIGVILNPEVTYARST
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCEEECCCCCEEEEEECCCEEEECCC
ATHDQQAAKMYDLFFNRIFLDPSIKGEYPKELFDVMKKHGITFDFTEEELNLIKDNTVDY
CCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEE
VGLNLYFPHRVKARTAGWNEQTPFHPAYYYEIFELPGKKMNPYRGWEIYPQIMYDMGIRM
EEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEE
KEEYDNIEWFIAENGMGVENEKRFKDASNMIQDDYRIEFIREHLKWLLKAVEEGVNCKGY
ECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
MLWAFTDNVSPMNAFKNRYGLVEIDLEDNRNRHLKKSAYWYKQLIESRKFEAENDENYK
EEEEEECCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MENVTIKVPNNFMLGAAVSAWQTEGWIGKRDSQDSYLDIWYKNNKHVWHNGYGPAGATNF
CCCEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHH
YQRYEEDIDYMKEIGLTHFRTSINWSRFLIDYENAIVDEEYAAYVDDVIEKLIQNGVEPM
HHHHHHHHHHHHHCCHHHHCCCCCHHHEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCE
ICLEHYEVPAVLFEKYGGWESKHVVELFVQYANKVFERYGDKVKHWFTFNEPIVVQTRVY
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHHH
LDAIRWPFEQSTKKWMQWNYNKVLATAKVVNLFKDLQLKDKNGAKIGVILNPEVTYARST
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCEEECCCCCEEEEEECCCEEEECCC
ATHDQQAAKMYDLFFNRIFLDPSIKGEYPKELFDVMKKHGITFDFTEEELNLIKDNTVDY
CCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEE
VGLNLYFPHRVKARTAGWNEQTPFHPAYYYEIFELPGKKMNPYRGWEIYPQIMYDMGIRM
EEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEE
KEEYDNIEWFIAENGMGVENEKRFKDASNMIQDDYRIEFIREHLKWLLKAVEEGVNCKGY
ECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
MLWAFTDNVSPMNAFKNRYGLVEIDLEDNRNRHLKKSAYWYKQLIESRKFEAENDENYK
EEEEEECCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]