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The map label for this gene is kynB [H]

Identifier: 23098210

GI number: 23098210

Start: 804561

End: 805208

Strand: Reverse

Name: kynB [H]

Synonym: OB0755

Alternate gene names: 23098210

Gene position: 805208-804561 (Counterclockwise)

Preceding gene: 23098211

Following gene: 23098209

Centisome position: 22.18

GC content: 42.28

Gene sequence:

>648_bases
ATGGGTGTATGGATTGATATTTCGCAACCGATAAATAATAATTTAGCTTGTTGGCCGGGGGATCAATCATTTCATTTTCA
TACACCGGTAACGAAGGAAATGACCGGTTCTGTGAATATTGGAAGGATCACGACGAGCACGCATGTGGGGACCCATGCGG
ATGCTCCTTATCATTTTATGGAAGATGGAAAACGGATTCTTGACCTGGAAATCGATCGGTATATTGGTCCTTGTAAAGTA
ATAGACCTCAGTGCATTTGACGAAATAGATGAAACAGCTTTAAAAAGTAAAGTGAAAGAAGATACAGAACGATTATTAAT
CCGGACATCACTGCCGAATAATCCGGAACAATTTCCGACTGATGTCACGCCAATTACATCGGACGGCGCTGCTTACATGC
ATTTTCTTGGAGTTAAACTGGTCGGTGTCGATACCCCTTCGGTAGATCCGCTTTCAAGTAAGGAGCTAGTTGGACATCAT
GCACTTTTCAAGCATGACATTAACATTTTAGAAAATGTCATGCTTGATCAGGTGGTTGAAGGCGACTATGAAATGATTGC
TCTGCCACTCCCGCTTCAGGATGCTGACGGAAGTCTGGTTAGGGCTGTGATTAAACCAATAAATGGAGGAAATCACGATG
CAAAATAA

Upstream 100 bases:

>100_bases
TACATTTGAAGATGTTTATGATTGCGTACAAATTTTTAAAACGATTATGGAAGATGAATTATATAAGCAATTTGAAAATG
TAAGGGAGGTTGTTTCCTAA

Downstream 100 bases:

>100_bases
ACATGAAGCATTTAAAAATGAAAGAAGTATTCATACAGACTTTAAAGAAAAGATGACATACAGTGATTATTTAGGATTGG
ACACATTATTGAGCAGTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MGVWIDISQPINNNLACWPGDQSFHFHTPVTKEMTGSVNIGRITTSTHVGTHADAPYHFMEDGKRILDLEIDRYIGPCKV
IDLSAFDEIDETALKSKVKEDTERLLIRTSLPNNPEQFPTDVTPITSDGAAYMHFLGVKLVGVDTPSVDPLSSKELVGHH
ALFKHDINILENVMLDQVVEGDYEMIALPLPLQDADGSLVRAVIKPINGGNHDAK

Sequences:

>Translated_215_residues
MGVWIDISQPINNNLACWPGDQSFHFHTPVTKEMTGSVNIGRITTSTHVGTHADAPYHFMEDGKRILDLEIDRYIGPCKV
IDLSAFDEIDETALKSKVKEDTERLLIRTSLPNNPEQFPTDVTPITSDGAAYMHFLGVKLVGVDTPSVDPLSSKELVGHH
ALFKHDINILENVMLDQVVEGDYEMIALPLPLQDADGSLVRAVIKPINGGNHDAK
>Mature_214_residues
GVWIDISQPINNNLACWPGDQSFHFHTPVTKEMTGSVNIGRITTSTHVGTHADAPYHFMEDGKRILDLEIDRYIGPCKVI
DLSAFDEIDETALKSKVKEDTERLLIRTSLPNNPEQFPTDVTPITSDGAAYMHFLGVKLVGVDTPSVDPLSSKELVGHHA
LFKHDINILENVMLDQVVEGDYEMIALPLPLQDADGSLVRAVIKPINGGNHDAK

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 23706; Mature: 23575

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVWIDISQPINNNLACWPGDQSFHFHTPVTKEMTGSVNIGRITTSTHVGTHADAPYHFM
CCEEEEECCCCCCCEEECCCCCCEEECCCCCHHHCCCEEECEEEECCCCCCCCCCCHHHH
EDGKRILDLEIDRYIGPCKVIDLSAFDEIDETALKSKVKEDTERLLIRTSLPNNPEQFPT
HCCCEEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
DVTPITSDGAAYMHFLGVKLVGVDTPSVDPLSSKELVGHHALFKHDINILENVMLDQVVE
CCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDYEMIALPLPLQDADGSLVRAVIKPINGGNHDAK
CCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GVWIDISQPINNNLACWPGDQSFHFHTPVTKEMTGSVNIGRITTSTHVGTHADAPYHFM
CEEEEECCCCCCCEEECCCCCCEEECCCCCHHHCCCEEECEEEECCCCCCCCCCCHHHH
EDGKRILDLEIDRYIGPCKVIDLSAFDEIDETALKSKVKEDTERLLIRTSLPNNPEQFPT
HCCCEEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
DVTPITSDGAAYMHFLGVKLVGVDTPSVDPLSSKELVGHHALFKHDINILENVMLDQVVE
CCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDYEMIALPLPLQDADGSLVRAVIKPINGGNHDAK
CCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA