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The map label for this gene is vpr [H]

Identifier: 23098188

GI number: 23098188

Start: 779998

End: 782220

Strand: Reverse

Name: vpr [H]

Synonym: OB0733

Alternate gene names: 23098188

Gene position: 782220-779998 (Counterclockwise)

Preceding gene: 23098189

Following gene: 23098187

Centisome position: 21.55

GC content: 38.15

Gene sequence:

>2223_bases
GTGAAAGCTCATAGAAAAATAGTATCAATAATAATGATTGCAGCCCTAGTGTTTTCGTTAGTGAATCTACCAGGTACGAA
AACTCTAGCAAACAATCAACAATCGCTAGAATCTGTACTATCAGATCTAACACCAGAACAAAAAGAAAATTATAAGCAGT
TGCAATCAGTAGAACAAGAAGGTCTTTTTCTATCACGTGACATAGACCTTAAAAGTGAGGAACAAGTGAAAGTGATTATT
CAACTTGATCATCACCCAGAGAAAATTGCAGTAATGGAGTCAGAACTAAAAGGTCAACGGATTTCTTCTAAAAAAGCAAA
ATCCGATGTAGAAGAAGATCAACAACAATTTAAGGACAACATTGCATCGATGTTTAAAGGTAAGAGCAGCAACCAATATA
CACTTGGCAAGTCTTATAAAAATGCGATGAATGGTATCGCAGTCGAACTTCCTGCCAATAAAATTAAAGAAGTATTGAAT
TTTGACGTCGTGCGAGCCATTTGGAGCGACGTAGAGGTGAAGATAGACCCTCCAATTAAGGAAGAAAAATTAGATAAAGA
ACAAATTGAGCCTTATATGATGGAAAGTATTCCATATTTACAAATTGATAAGTTACATACAGAAGGATATACAGGTGAAG
GTATAAAGGTCGGGGTATTGGATACTGGTATTGACTACAATCATCCAGATTTAGAGGGAGTCTATGCAGGTGGATACGAT
ATGGTAGATGACGACAATGACCCGATGGAAACAACCTATCAAGATTGGATAGATTCGGAACAACCAGAGTACAACGGAAG
CAATTCTTATTATACAGAGCATGGTACACATGTTGCAGGAACCATTGCTGGCGAAGGAGATAATTCCAGTGAACATCGTA
TTAAAGGTGTTGCGCCTGAGGTAGATTTATATGGTTATAGAGTTCTCGGCCCGTACGGAAGTGGTACAAGTGAAAATGTT
ATTGCTGGTATTGATCGTGCAATAGCGGAAGGGATGGATGTCATTAATCTGTCATTAGGAGCAATGGTAAATGATCCTCT
ATTCCCTACGAGTGTAGCAGTTAATAATGCTGTGTTAAGTGGTGTCACTGCCGTTGTATCGGCTGGAAATGCAGGTAATC
AGGATTTCACCTTAGGATCACCAGGAACAGCTTCTCTAGCGTTAACCGTAGGAGCTAGTGATGTTCCGGTTGATATTGCA
ACATTCGACGGTGCATACGGTTCAGAGACAGTTGATTTACAACTGATGGCGAAGCATTTTGATGATGATCTATCATCATT
AGTAGATACGAATCTACCAATTGTGGATGTAGGTTTTGGTAGAGCGTCTGATTATAATGACAGTCCGAGTGTCGAAGGAA
AAATTGCATTGATAAGCAGAGGAGAAATTCCTTTTGTGGACAAGATTACGACGACAAAAGAACAAGGTGCAGAAGCGATC
CTTCTTTATAATAATGTCGATGAAGGACATATTCCTAGCTATCTTGCTGAAGGTGTAGATTATATTCCTACCTTTTCTTT
AACAAAAGATGATGGTGAAGCGCTAAAAGGAATTCTTGAGACAGATGAGACCTTTACATTTAGTAATTTAGACGCTATTA
CAACTGAAGGAGATAGATTAGCAGAATTTAGTTCACGTGGTCCTTCGAAAGTGAATTATGATATAAAGCCGGAAATTGTA
GCTCCCGGTGTCAATATACAATCAACTGTTCCATCCTATATTAATGATCAGGAAAATGGAACGTATACATTTGCTTATCA
GCGATTGTCTGGAACATCGATGGCTTCTCCACATATTGCTGGAATTGCCGCTCTTCTCCTACAATCAAATGATCAATACG
AACCAGAAGATGTTCGCTCGCTATTAATGAATACTGCTGATCCATTAAACGGTGATTATAGTGTTTATGAAGTGGGTGCT
GGAAGAGTAGATCCGTATGAAGCTGTTCATTCAGATTTGAATTTCCAAGTGATCGATGAAACAACCAATTTAGAGAATGG
CAATGAAGTAGAGATTGAAGAAATAACAGGTGGAATGAGTTTCGGCTTAAAGTATGTCGACAAGAAAGATTTGAAATTGA
AGAAAGAGTTAGAGATTACGAACGCAGGTGATCAAGATAAAGTATTGAAGGGGAATGTCGAGTTTACCAATCAATCATTA
GATCCAGAAGAAAACAAAGTGAACTTCTCGATAAAGAATAATGTGAAAATCAAATCAGGGTAA

Upstream 100 bases:

>100_bases
TTAATCTATCTTTGTACCTATCGTGTTTTCCCAATACGCAATAGCAAATTGCTGTGATACACTTAAAGCGTTTACAACAA
CATTATAGGAGGGATTCGAA

Downstream 100 bases:

>100_bases
ACGAAAAAAATAAAAGCATCCTTAAGTGTTCCTGCATCAAGTGAAAAAGGCTACTATGAAGGATATATTCATTATGAAAA
TGTCGAAGATTCATCGGAAA

Product: minor serine proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 740; Mature: 740

Protein sequence:

>740_residues
MKAHRKIVSIIMIAALVFSLVNLPGTKTLANNQQSLESVLSDLTPEQKENYKQLQSVEQEGLFLSRDIDLKSEEQVKVII
QLDHHPEKIAVMESELKGQRISSKKAKSDVEEDQQQFKDNIASMFKGKSSNQYTLGKSYKNAMNGIAVELPANKIKEVLN
FDVVRAIWSDVEVKIDPPIKEEKLDKEQIEPYMMESIPYLQIDKLHTEGYTGEGIKVGVLDTGIDYNHPDLEGVYAGGYD
MVDDDNDPMETTYQDWIDSEQPEYNGSNSYYTEHGTHVAGTIAGEGDNSSEHRIKGVAPEVDLYGYRVLGPYGSGTSENV
IAGIDRAIAEGMDVINLSLGAMVNDPLFPTSVAVNNAVLSGVTAVVSAGNAGNQDFTLGSPGTASLALTVGASDVPVDIA
TFDGAYGSETVDLQLMAKHFDDDLSSLVDTNLPIVDVGFGRASDYNDSPSVEGKIALISRGEIPFVDKITTTKEQGAEAI
LLYNNVDEGHIPSYLAEGVDYIPTFSLTKDDGEALKGILETDETFTFSNLDAITTEGDRLAEFSSRGPSKVNYDIKPEIV
APGVNIQSTVPSYINDQENGTYTFAYQRLSGTSMASPHIAGIAALLLQSNDQYEPEDVRSLLMNTADPLNGDYSVYEVGA
GRVDPYEAVHSDLNFQVIDETTNLENGNEVEIEEITGGMSFGLKYVDKKDLKLKKELEITNAGDQDKVLKGNVEFTNQSL
DPEENKVNFSIKNNVKIKSG

Sequences:

>Translated_740_residues
MKAHRKIVSIIMIAALVFSLVNLPGTKTLANNQQSLESVLSDLTPEQKENYKQLQSVEQEGLFLSRDIDLKSEEQVKVII
QLDHHPEKIAVMESELKGQRISSKKAKSDVEEDQQQFKDNIASMFKGKSSNQYTLGKSYKNAMNGIAVELPANKIKEVLN
FDVVRAIWSDVEVKIDPPIKEEKLDKEQIEPYMMESIPYLQIDKLHTEGYTGEGIKVGVLDTGIDYNHPDLEGVYAGGYD
MVDDDNDPMETTYQDWIDSEQPEYNGSNSYYTEHGTHVAGTIAGEGDNSSEHRIKGVAPEVDLYGYRVLGPYGSGTSENV
IAGIDRAIAEGMDVINLSLGAMVNDPLFPTSVAVNNAVLSGVTAVVSAGNAGNQDFTLGSPGTASLALTVGASDVPVDIA
TFDGAYGSETVDLQLMAKHFDDDLSSLVDTNLPIVDVGFGRASDYNDSPSVEGKIALISRGEIPFVDKITTTKEQGAEAI
LLYNNVDEGHIPSYLAEGVDYIPTFSLTKDDGEALKGILETDETFTFSNLDAITTEGDRLAEFSSRGPSKVNYDIKPEIV
APGVNIQSTVPSYINDQENGTYTFAYQRLSGTSMASPHIAGIAALLLQSNDQYEPEDVRSLLMNTADPLNGDYSVYEVGA
GRVDPYEAVHSDLNFQVIDETTNLENGNEVEIEEITGGMSFGLKYVDKKDLKLKKELEITNAGDQDKVLKGNVEFTNQSL
DPEENKVNFSIKNNVKIKSG
>Mature_740_residues
MKAHRKIVSIIMIAALVFSLVNLPGTKTLANNQQSLESVLSDLTPEQKENYKQLQSVEQEGLFLSRDIDLKSEEQVKVII
QLDHHPEKIAVMESELKGQRISSKKAKSDVEEDQQQFKDNIASMFKGKSSNQYTLGKSYKNAMNGIAVELPANKIKEVLN
FDVVRAIWSDVEVKIDPPIKEEKLDKEQIEPYMMESIPYLQIDKLHTEGYTGEGIKVGVLDTGIDYNHPDLEGVYAGGYD
MVDDDNDPMETTYQDWIDSEQPEYNGSNSYYTEHGTHVAGTIAGEGDNSSEHRIKGVAPEVDLYGYRVLGPYGSGTSENV
IAGIDRAIAEGMDVINLSLGAMVNDPLFPTSVAVNNAVLSGVTAVVSAGNAGNQDFTLGSPGTASLALTVGASDVPVDIA
TFDGAYGSETVDLQLMAKHFDDDLSSLVDTNLPIVDVGFGRASDYNDSPSVEGKIALISRGEIPFVDKITTTKEQGAEAI
LLYNNVDEGHIPSYLAEGVDYIPTFSLTKDDGEALKGILETDETFTFSNLDAITTEGDRLAEFSSRGPSKVNYDIKPEIV
APGVNIQSTVPSYINDQENGTYTFAYQRLSGTSMASPHIAGIAALLLQSNDQYEPEDVRSLLMNTADPLNGDYSVYEVGA
GRVDPYEAVHSDLNFQVIDETTNLENGNEVEIEEITGGMSFGLKYVDKKDLKLKKELEITNAGDQDKVLKGNVEFTNQSL
DPEENKVNFSIKNNVKIKSG

Specific function: Not required for growth or sporulation [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=248, Percent_Identity=30.241935483871, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324576, Length=207, Percent_Identity=33.8164251207729, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319893, Length=203, Percent_Identity=30.5418719211823, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259
- InterPro:   IPR003137 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF02225 PA; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 80770; Mature: 80770

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAHRKIVSIIMIAALVFSLVNLPGTKTLANNQQSLESVLSDLTPEQKENYKQLQSVEQE
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GLFLSRDIDLKSEEQVKVIIQLDHHPEKIAVMESELKGQRISSKKAKSDVEEDQQQFKDN
CCEEEECCCCCCCCEEEEEEEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASMFKGKSSNQYTLGKSYKNAMNGIAVELPANKIKEVLNFDVVRAIWSDVEVKIDPPIK
HHHHHCCCCCCCEECCHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCC
EEKLDKEQIEPYMMESIPYLQIDKLHTEGYTGEGIKVGVLDTGIDYNHPDLEGVYAGGYD
HHHCCHHHCCHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCC
MVDDDNDPMETTYQDWIDSEQPEYNGSNSYYTEHGTHVAGTIAGEGDNSSEHRIKGVAPE
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCEEECCCCC
VDLYGYRVLGPYGSGTSENVIAGIDRAIAEGMDVINLSLGAMVNDPLFPTSVAVNNAVLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCHHHHHHHHHH
GVTAVVSAGNAGNQDFTLGSPGTASLALTVGASDVPVDIATFDGAYGSETVDLQLMAKHF
HHHHHHCCCCCCCCCEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEHHHHHHHH
DDDLSSLVDTNLPIVDVGFGRASDYNDSPSVEGKIALISRGEIPFVDKITTTKEQGAEAI
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCCEE
LLYNNVDEGHIPSYLAEGVDYIPTFSLTKDDGEALKGILETDETFTFSNLDAITTEGDRL
EEEECCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCEEEECCCCEEECCCHHH
AEFSSRGPSKVNYDIKPEIVAPGVNIQSTVPSYINDQENGTYTFAYQRLSGTSMASPHIA
HHHHCCCCCCCCCCCCCCEEECCCCHHHCCCHHHCCCCCCEEEEEEEEECCCCCCCCHHH
GIAALLLQSNDQYEPEDVRSLLMNTADPLNGDYSVYEVGAGRVDPYEAVHSDLNFQVIDE
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCEEEEEC
TTNLENGNEVEIEEITGGMSFGLKYVDKKDLKLKKELEITNAGDQDKVLKGNVEFTNQSL
CCCCCCCCEEEEHHHCCCHHHCEEECCCCCCCEEEEEEECCCCCCCCEEECCEEECCCCC
DPEENKVNFSIKNNVKIKSG
CCCCCEEEEEEECCEEEECC
>Mature Secondary Structure
MKAHRKIVSIIMIAALVFSLVNLPGTKTLANNQQSLESVLSDLTPEQKENYKQLQSVEQE
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GLFLSRDIDLKSEEQVKVIIQLDHHPEKIAVMESELKGQRISSKKAKSDVEEDQQQFKDN
CCEEEECCCCCCCCEEEEEEEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASMFKGKSSNQYTLGKSYKNAMNGIAVELPANKIKEVLNFDVVRAIWSDVEVKIDPPIK
HHHHHCCCCCCCEECCHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCC
EEKLDKEQIEPYMMESIPYLQIDKLHTEGYTGEGIKVGVLDTGIDYNHPDLEGVYAGGYD
HHHCCHHHCCHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCC
MVDDDNDPMETTYQDWIDSEQPEYNGSNSYYTEHGTHVAGTIAGEGDNSSEHRIKGVAPE
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCEEECCCCC
VDLYGYRVLGPYGSGTSENVIAGIDRAIAEGMDVINLSLGAMVNDPLFPTSVAVNNAVLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCHHHHHHHHHH
GVTAVVSAGNAGNQDFTLGSPGTASLALTVGASDVPVDIATFDGAYGSETVDLQLMAKHF
HHHHHHCCCCCCCCCEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEHHHHHHHH
DDDLSSLVDTNLPIVDVGFGRASDYNDSPSVEGKIALISRGEIPFVDKITTTKEQGAEAI
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCCEE
LLYNNVDEGHIPSYLAEGVDYIPTFSLTKDDGEALKGILETDETFTFSNLDAITTEGDRL
EEEECCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHHCCCCEEEECCCCEEECCCHHH
AEFSSRGPSKVNYDIKPEIVAPGVNIQSTVPSYINDQENGTYTFAYQRLSGTSMASPHIA
HHHHCCCCCCCCCCCCCCEEECCCCHHHCCCHHHCCCCCCEEEEEEEEECCCCCCCCHHH
GIAALLLQSNDQYEPEDVRSLLMNTADPLNGDYSVYEVGAGRVDPYEAVHSDLNFQVIDE
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCEEEEEC
TTNLENGNEVEIEEITGGMSFGLKYVDKKDLKLKKELEITNAGDQDKVLKGNVEFTNQSL
CCCCCCCCEEEEHHHCCCHHHCEEECCCCCCCEEEEEEECCCCCCCCEEECCEEECCCCC
DPEENKVNFSIKNNVKIKSG
CCCCCEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1938892; 7934828; 9384377; 10658653 [H]