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The map label for this gene is pbuG [H]

Identifier: 23098178

GI number: 23098178

Start: 769883

End: 771187

Strand: Direct

Name: pbuG [H]

Synonym: OB0723

Alternate gene names: 23098178

Gene position: 769883-771187 (Clockwise)

Preceding gene: 23098177

Following gene: 23098180

Centisome position: 21.21

GC content: 37.32

Gene sequence:

>1305_bases
ATGAACAAGTATTTTCAGTTAGATAAGTTAGGTACAAACATTCGAAGAGAGTTTGTTGCAGGCTTGACTACTTTCTTAGC
AATGGCATATATATTATTTGTTAATCCTAGTATGCTAAGTGAAACAGGCATGGATGCTGATGCTGTTTTTGCTGCAACAG
CAATTGCTGCAGCGATAGGTACATTAGTAATGGGGTTAGTTGCGAAATATCCAGTAGCGTTAGCTCCGGGTATGGGACTT
AATGCATTCTTTACGTATACGGTTGTAATTGGATTTGGTATACCTTGGGAGACTGCACTTGCAGGTGTGTTAGCTTCAGG
TCTTATATTTATCATTTTAACGTTATCTGGTATTCGTGAAAAAGTCATTAATGCCATTCCTTCAAGTTTAAAATTAGCAG
TTGGTTCAGGTATTGGTCTATTTATCGCTTTTATTGGTCTGCAAAATGCCAATCTTGTGCAAGCCGATCCATCTACACTT
CTAGCGTTAGGTGATCTTACTTCACCTACTGTTATGCTTGCGATATTCGGCCTTGTAGTTTCTGTTATTCTATTAGCTTA
TGGTGTGAAGGCAGGAATATTTTATGGAATGATTATTACTGCGATCGCTGGTATGCTATTTGGATTAATTCAACCACCTA
CTGGAATCAATGATATTGTCAGTGGAGTTCCAAGTTTAGCTCCTACTTTTGGACAAGCTATTCTGCATTTTGGTGAGATT
TTTACTTTAGAAATGTTAGTTGTTATTTTAACTTTCTTATTTGTAGACTTTTTTGATACAGCAGGTACGCTTGTAGCAGT
TGCATCAAAAGCAGGGATTATGAAAGATAATAAGTTACCTCGAGCTGGTAAAGCATTATTCTCTGATGCTTCAGCTACAG
TTGTTGGGGCAGTTGTTGGTACATCGACAACTACTGCGTATGTAGAGTCTACAACTGGGGTAAGTGTTGGAGGACGTTCT
GGACTAACTTCTGTGTTTACTGCACTGTTTTTCTTACTAGCATTATTCTTCTCTCCTTTATTAGGAGTTGTTACAAGTGA
GGTTACTGCACCAGCTTTAATTATTGTCGGTGTACTCATGGTAAGTGCTTTAAAAGATATCCCTTGGGATGAGTTTGAGA
TTGCTGTTCCTGCATTCTTTACCGTATTAATGATGCCACTAACGTACAGTATTGCTACAGGTATTGCAATTGGCTTTATC
TTCTACCCAATTACGATGTTAGTAAAAGGACGAGGAAAAGAAATTCATCCGATTATGTATGGCTTATTCGTCATATTTAT
TCTATACTTCATATTTTTAAATTAG

Upstream 100 bases:

>100_bases
GTATCTAGATTTTAAGATATGCAGATATATTTCCTGTAGTTATTGTAGAAGCGCATGGCAATCCCAAGTGCTTCTATTAT
TTTTGGGGGGAATTAGATAA

Downstream 100 bases:

>100_bases
TTGTAAATATAAAAAGGGTTAACCAATTTTGGTTAACCCTTTTTGCATGCTGTATGATAAAATGATTTACAATGATCTAT
TCCGAACCAGGTGCTGTTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNKYFQLDKLGTNIRREFVAGLTTFLAMAYILFVNPSMLSETGMDADAVFAATAIAAAIGTLVMGLVAKYPVALAPGMGL
NAFFTYTVVIGFGIPWETALAGVLASGLIFIILTLSGIREKVINAIPSSLKLAVGSGIGLFIAFIGLQNANLVQADPSTL
LALGDLTSPTVMLAIFGLVVSVILLAYGVKAGIFYGMIITAIAGMLFGLIQPPTGINDIVSGVPSLAPTFGQAILHFGEI
FTLEMLVVILTFLFVDFFDTAGTLVAVASKAGIMKDNKLPRAGKALFSDASATVVGAVVGTSTTTAYVESTTGVSVGGRS
GLTSVFTALFFLLALFFSPLLGVVTSEVTAPALIIVGVLMVSALKDIPWDEFEIAVPAFFTVLMMPLTYSIATGIAIGFI
FYPITMLVKGRGKEIHPIMYGLFVIFILYFIFLN

Sequences:

>Translated_434_residues
MNKYFQLDKLGTNIRREFVAGLTTFLAMAYILFVNPSMLSETGMDADAVFAATAIAAAIGTLVMGLVAKYPVALAPGMGL
NAFFTYTVVIGFGIPWETALAGVLASGLIFIILTLSGIREKVINAIPSSLKLAVGSGIGLFIAFIGLQNANLVQADPSTL
LALGDLTSPTVMLAIFGLVVSVILLAYGVKAGIFYGMIITAIAGMLFGLIQPPTGINDIVSGVPSLAPTFGQAILHFGEI
FTLEMLVVILTFLFVDFFDTAGTLVAVASKAGIMKDNKLPRAGKALFSDASATVVGAVVGTSTTTAYVESTTGVSVGGRS
GLTSVFTALFFLLALFFSPLLGVVTSEVTAPALIIVGVLMVSALKDIPWDEFEIAVPAFFTVLMMPLTYSIATGIAIGFI
FYPITMLVKGRGKEIHPIMYGLFVIFILYFIFLN
>Mature_434_residues
MNKYFQLDKLGTNIRREFVAGLTTFLAMAYILFVNPSMLSETGMDADAVFAATAIAAAIGTLVMGLVAKYPVALAPGMGL
NAFFTYTVVIGFGIPWETALAGVLASGLIFIILTLSGIREKVINAIPSSLKLAVGSGIGLFIAFIGLQNANLVQADPSTL
LALGDLTSPTVMLAIFGLVVSVILLAYGVKAGIFYGMIITAIAGMLFGLIQPPTGINDIVSGVPSLAPTFGQAILHFGEI
FTLEMLVVILTFLFVDFFDTAGTLVAVASKAGIMKDNKLPRAGKALFSDASATVVGAVVGTSTTTAYVESTTGVSVGGRS
GLTSVFTALFFLLALFFSPLLGVVTSEVTAPALIIVGVLMVSALKDIPWDEFEIAVPAFFTVLMMPLTYSIATGIAIGFI
FYPITMLVKGRGKEIHPIMYGLFVIFILYFIFLN

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=422, Percent_Identity=43.3649289099526, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1790150, Length=435, Percent_Identity=42.2988505747126, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1790499, Length=422, Percent_Identity=35.0710900473934, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI48994909, Length=438, Percent_Identity=33.5616438356164, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45665; Mature: 45665

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYFQLDKLGTNIRREFVAGLTTFLAMAYILFVNPSMLSETGMDADAVFAATAIAAAIG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHH
TLVMGLVAKYPVALAPGMGLNAFFTYTVVIGFGIPWETALAGVLASGLIFIILTLSGIRE
HHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVINAIPSSLKLAVGSGIGLFIAFIGLQNANLVQADPSTLLALGDLTSPTVMLAIFGLVV
HHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHEEEECCCCCHHHHHHHHHHHH
SVILLAYGVKAGIFYGMIITAIAGMLFGLIQPPTGINDIVSGVPSLAPTFGQAILHFGEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
FTLEMLVVILTFLFVDFFDTAGTLVAVASKAGIMKDNKLPRAGKALFSDASATVVGAVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHC
TSTTTAYVESTTGVSVGGRSGLTSVFTALFFLLALFFSPLLGVVTSEVTAPALIIVGVLM
CCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSALKDIPWDEFEIAVPAFFTVLMMPLTYSIATGIAIGFIFYPITMLVKGRGKEIHPIMY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GLFVIFILYFIFLN
HHHHHHHHHHHHCC
>Mature Secondary Structure
MNKYFQLDKLGTNIRREFVAGLTTFLAMAYILFVNPSMLSETGMDADAVFAATAIAAAIG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHH
TLVMGLVAKYPVALAPGMGLNAFFTYTVVIGFGIPWETALAGVLASGLIFIILTLSGIRE
HHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVINAIPSSLKLAVGSGIGLFIAFIGLQNANLVQADPSTLLALGDLTSPTVMLAIFGLVV
HHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHEEEECCCCCHHHHHHHHHHHH
SVILLAYGVKAGIFYGMIITAIAGMLFGLIQPPTGINDIVSGVPSLAPTFGQAILHFGEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
FTLEMLVVILTFLFVDFFDTAGTLVAVASKAGIMKDNKLPRAGKALFSDASATVVGAVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHC
TSTTTAYVESTTGVSVGGRSGLTSVFTALFFLLALFFSPLLGVVTSEVTAPALIIVGVLM
CCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSALKDIPWDEFEIAVPAFFTVLMMPLTYSIATGIAIGFIFYPITMLVKGRGKEIHPIMY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GLFVIFILYFIFLN
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]