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The map label for this gene is licC [H]

Identifier: 23098153

GI number: 23098153

Start: 736712

End: 737965

Strand: Direct

Name: licC [H]

Synonym: OB0698

Alternate gene names: 23098153

Gene position: 736712-737965 (Clockwise)

Preceding gene: 23098152

Following gene: 23098154

Centisome position: 20.29

GC content: 37.48

Gene sequence:

>1254_bases
GTGACAAAGTTTCAACTATTTATGGAAAAGTATTTCATGCCAGTGGCAGGAAAACTTGCAGAGCAACGGCATCTAAAGGC
AATCCGTGATGGAATTATAGCAGTTATGCCATTATTGATTATCGGAAGTATTTTTTTAATTATTTCTTCACCACCAATTA
AATCGTGGGCTGAGTTTATGTCACAATATGCTGCAACATTGAGTATTCCAGTGAATGCAACATTCGGGTTATTAGGTTTG
GTCGCTGTATTTTCCATTGCTTATAGCTTGGCCCAGAGTTATAAAATGGATGGATTGTCTGCAGGTGTACTTGCTATATC
GGCATTTTTTGTAGCTACACCATTAACGGAAGATGGGAATATACCATTGAATTTAATGGGCAGTGAAGGTCTATTTATTG
CGATTGTTTTAGCTATTTTCACGGTAGAAGTATTTCGGTTTTTCGATCGAAGGAAATTAGTAATAAGAATGCCTGATACC
GTCCCTCCATCTGTATGGAGAGCATTTACTGCATTAATACCTGGTGCAGTTATTATTTCTATTGTATTTGGCATAGATGT
ATTACTAGCGCATTGGTGGGAGCTATCTTTGCATGATATTGTTGCGACGGTTTTAAGGCAACCATTAGAAATGCTTGGTG
CTAGTTTTTGGGGTGCAATGGTAGCCATTATATTAATTCATTTATTATGGGCATTTGGAATTCATGGTATATCGGTTGTT
GCAAGTGTTATGGCCCCGATTTGGTATAGTCTAACTGAACAAAATGTAGCTGCTCATCAAGCAGGTGAAGAATTGCCTCA
TATTATTGGCCAACCTTTTATGGCTATTTGGTGGGCGGTCGGTGGATCTGGGATGGTTTTAGCCTTAACACTACTATTTT
TGTTATTCTCAAAATCAAGACACTTGAAAAATGTAGGGAAAGGATCAATTGGTGCAAGCCTTTTTAATATTAGTGAACCG
ACGATATTTGGAGCTCCTGTGGTAATGAATCCGATATTAATGGTTCCTTTTATTCTCGCTCCTTTGACAGTTGGAATTAT
TACTTACGTTTCAATGGCTATAGGACTGGTAGGCAAACCATATGTAATCGTACCATGGACCACTCCAGCACCATTTTCTG
GTCTACTTACGACAGGGGAATTCAGTGGACTTATTTTAATGATTGTAAATATAATCGTAGCAATGTTAATCTATTATCCT
TTCTTTAAGATGTATGATCGACAGTTATTAAAAGAAGAAGTAAAAGGTGAATGA

Upstream 100 bases:

>100_bases
AATTCCTGTAGTTATACATTCATATGCATAGAATACAAGCTTGTAAATTTCAGGAGAACTATTAACCATTTGAAAACATT
TTCAAAAGGGGGGTATTTTG

Downstream 100 bases:

>100_bases
GTAGGAACATGTATTTTATGATTTATGATATTGACGATAATATATCGCACCGCTATAATTAACTTCATAATAGGAAGTGC
GGAAGGAGAATTAATAAAGA

Product: PTS system cellobiose-specific enzyme II C component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTKFQLFMEKYFMPVAGKLAEQRHLKAIRDGIIAVMPLLIIGSIFLIISSPPIKSWAEFMSQYAATLSIPVNATFGLLGL
VAVFSIAYSLAQSYKMDGLSAGVLAISAFFVATPLTEDGNIPLNLMGSEGLFIAIVLAIFTVEVFRFFDRRKLVIRMPDT
VPPSVWRAFTALIPGAVIISIVFGIDVLLAHWWELSLHDIVATVLRQPLEMLGASFWGAMVAIILIHLLWAFGIHGISVV
ASVMAPIWYSLTEQNVAAHQAGEELPHIIGQPFMAIWWAVGGSGMVLALTLLFLLFSKSRHLKNVGKGSIGASLFNISEP
TIFGAPVVMNPILMVPFILAPLTVGIITYVSMAIGLVGKPYVIVPWTTPAPFSGLLTTGEFSGLILMIVNIIVAMLIYYP
FFKMYDRQLLKEEVKGE

Sequences:

>Translated_417_residues
MTKFQLFMEKYFMPVAGKLAEQRHLKAIRDGIIAVMPLLIIGSIFLIISSPPIKSWAEFMSQYAATLSIPVNATFGLLGL
VAVFSIAYSLAQSYKMDGLSAGVLAISAFFVATPLTEDGNIPLNLMGSEGLFIAIVLAIFTVEVFRFFDRRKLVIRMPDT
VPPSVWRAFTALIPGAVIISIVFGIDVLLAHWWELSLHDIVATVLRQPLEMLGASFWGAMVAIILIHLLWAFGIHGISVV
ASVMAPIWYSLTEQNVAAHQAGEELPHIIGQPFMAIWWAVGGSGMVLALTLLFLLFSKSRHLKNVGKGSIGASLFNISEP
TIFGAPVVMNPILMVPFILAPLTVGIITYVSMAIGLVGKPYVIVPWTTPAPFSGLLTTGEFSGLILMIVNIIVAMLIYYP
FFKMYDRQLLKEEVKGE
>Mature_416_residues
TKFQLFMEKYFMPVAGKLAEQRHLKAIRDGIIAVMPLLIIGSIFLIISSPPIKSWAEFMSQYAATLSIPVNATFGLLGLV
AVFSIAYSLAQSYKMDGLSAGVLAISAFFVATPLTEDGNIPLNLMGSEGLFIAIVLAIFTVEVFRFFDRRKLVIRMPDTV
PPSVWRAFTALIPGAVIISIVFGIDVLLAHWWELSLHDIVATVLRQPLEMLGASFWGAMVAIILIHLLWAFGIHGISVVA
SVMAPIWYSLTEQNVAAHQAGEELPHIIGQPFMAIWWAVGGSGMVLALTLLFLLFSKSRHLKNVGKGSIGASLFNISEPT
IFGAPVVMNPILMVPFILAPLTVGIITYVSMAIGLVGKPYVIVPWTTPAPFSGLLTTGEFSGLILMIVNIIVAMLIYYPF
FKMYDRQLLKEEVKGE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=442, Percent_Identity=31.2217194570136, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 45631; Mature: 45500

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKFQLFMEKYFMPVAGKLAEQRHLKAIRDGIIAVMPLLIIGSIFLIISSPPIKSWAEFM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SQYAATLSIPVNATFGLLGLVAVFSIAYSLAQSYKMDGLSAGVLAISAFFVATPLTEDGN
HHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
IPLNLMGSEGLFIAIVLAIFTVEVFRFFDRRKLVIRMPDTVPPSVWRAFTALIPGAVIIS
CCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
IVFGIDVLLAHWWELSLHDIVATVLRQPLEMLGASFWGAMVAIILIHLLWAFGIHGISVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVMAPIWYSLTEQNVAAHQAGEELPHIIGQPFMAIWWAVGGSGMVLALTLLFLLFSKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
HLKNVGKGSIGASLFNISEPTIFGAPVVMNPILMVPFILAPLTVGIITYVSMAIGLVGKP
HHHHCCCCCCCHHHEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YVIVPWTTPAPFSGLLTTGEFSGLILMIVNIIVAMLIYYPFFKMYDRQLLKEEVKGE
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]