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The map label for this gene is ywcF [H]

Identifier: 23098104

GI number: 23098104

Start: 683669

End: 684838

Strand: Direct

Name: ywcF [H]

Synonym: OB0649

Alternate gene names: 23098104

Gene position: 683669-684838 (Clockwise)

Preceding gene: 161501983

Following gene: 23098107

Centisome position: 18.83

GC content: 34.44

Gene sequence:

>1170_bases
ATGAATAAAAAACAAAATTATTATTTTCAAACTGATTTGATTCTACTCTTTTTAGGATTTGTAATCATTAGTCTATTGGC
TATTTATAACGCGCAGCAAATTGATCAAGCTAATACGAATTTTGTCATACGGCAAATTGCTTTTTTTAGTATTGGTGTTT
GTTTTGTAGCTGCGATTCAATTTATCGACCTCGAACAGTTGTATAGAGGAAGTATATATATTTATATAGGTGGAGTTCTC
TTGTTAGGGCTGTTACTTATCAGTCCTGATGCAATTGCAAGGGAAATTAATGGTGCAAATAGTTGGTTTACCTTACCTGG
ATTATCCATTCAACCCGCCGAATTTGCCAAAATGTCGACGATATTATTTCTAGCAGCAACGATAACGGGACATAAAGAAA
AGACAGAAGTTCAAACGATGAAAACGGATATTATGTTATTACTTAAACTAATAATCTATACAATGATACCAGTCGGATTA
ATTATGCTACAACCTGATTTTGGTACCTCGATGGTGTATTTGTTTATTGCAGGAATGATGATAATTTTATCAGGTATTAA
CTGGAGGATTATTGTTTCCTTAATAGTTGGCTTGGTATCTCTAGCAGGAGCTGCTATTGGAGCAATTATTCGATTTCCGC
AGTTTGCAATTGATGTTCTTGGAGTAGCACCATATCAAGTGGATCGAATTATGACATGGTTTGATCCGTCACAACAATCA
GCAGATGCGACATTTCAGTTTGAACGATCACATATGTCATTGGGTTCTGGACAATTATTTGGTAAGGGAATGAGTAGTCT
AGAAGTACAATATCCAGAAGCACATACAGATTTTATCTTTTCTGTAATAGGAGAGAGCTTTGGATTTATTGGAAGTGCCA
TTGTAATTTTTCTTTACTTTATGCTTCTATACCGTTTAGTAACCTTAGGCTTAAGCATCTATAAACATTCTCCTTTTGGC
ACATATTTCTGCTTTGGATTTTTAAGTTTGATGCTGGTCCATGTGTTTCAAAATATCGGAATGACAATTGGAATTATGCC
AATAACAGGAATTCCATTGCTACTTATTAGTTATGGAGGTAGTTCTGTCATGTCCACCATGTTAGGATTGGCAGTAGTTT
ACCGAGTTGCAGTTGAACATACGATACAAAATGATTATCTATTTAAATAA

Upstream 100 bases:

>100_bases
TTGCTGATTCGAGGTTTTTAGACATTTTTCGAGCTTTTCGTTGTGGATAAGTATTTGGTTAAAGAAGGATATTAACAGGA
AGAAATTTGGTGGGAATCCG

Downstream 100 bases:

>100_bases
AAGCTATAAAAAAACTCTCTAAATCCAACATTGTGGATAAAGAGAGTTTTTTACTCTTATTATGAGTTTGATTCAACTAG
GTTGCCTATGAAATTGGTCG

Product: cell-division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNKKQNYYFQTDLILLFLGFVIISLLAIYNAQQIDQANTNFVIRQIAFFSIGVCFVAAIQFIDLEQLYRGSIYIYIGGVL
LLGLLLISPDAIAREINGANSWFTLPGLSIQPAEFAKMSTILFLAATITGHKEKTEVQTMKTDIMLLLKLIIYTMIPVGL
IMLQPDFGTSMVYLFIAGMMIILSGINWRIIVSLIVGLVSLAGAAIGAIIRFPQFAIDVLGVAPYQVDRIMTWFDPSQQS
ADATFQFERSHMSLGSGQLFGKGMSSLEVQYPEAHTDFIFSVIGESFGFIGSAIVIFLYFMLLYRLVTLGLSIYKHSPFG
TYFCFGFLSLMLVHVFQNIGMTIGIMPITGIPLLLISYGGSSVMSTMLGLAVVYRVAVEHTIQNDYLFK

Sequences:

>Translated_389_residues
MNKKQNYYFQTDLILLFLGFVIISLLAIYNAQQIDQANTNFVIRQIAFFSIGVCFVAAIQFIDLEQLYRGSIYIYIGGVL
LLGLLLISPDAIAREINGANSWFTLPGLSIQPAEFAKMSTILFLAATITGHKEKTEVQTMKTDIMLLLKLIIYTMIPVGL
IMLQPDFGTSMVYLFIAGMMIILSGINWRIIVSLIVGLVSLAGAAIGAIIRFPQFAIDVLGVAPYQVDRIMTWFDPSQQS
ADATFQFERSHMSLGSGQLFGKGMSSLEVQYPEAHTDFIFSVIGESFGFIGSAIVIFLYFMLLYRLVTLGLSIYKHSPFG
TYFCFGFLSLMLVHVFQNIGMTIGIMPITGIPLLLISYGGSSVMSTMLGLAVVYRVAVEHTIQNDYLFK
>Mature_389_residues
MNKKQNYYFQTDLILLFLGFVIISLLAIYNAQQIDQANTNFVIRQIAFFSIGVCFVAAIQFIDLEQLYRGSIYIYIGGVL
LLGLLLISPDAIAREINGANSWFTLPGLSIQPAEFAKMSTILFLAATITGHKEKTEVQTMKTDIMLLLKLIIYTMIPVGL
IMLQPDFGTSMVYLFIAGMMIILSGINWRIIVSLIVGLVSLAGAAIGAIIRFPQFAIDVLGVAPYQVDRIMTWFDPSQQS
ADATFQFERSHMSLGSGQLFGKGMSSLEVQYPEAHTDFIFSVIGESFGFIGSAIVIFLYFMLLYRLVTLGLSIYKHSPFG
TYFCFGFLSLMLVHVFQNIGMTIGIMPITGIPLLLISYGGSSVMSTMLGLAVVYRVAVEHTIQNDYLFK

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=390, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786277, Length=398, Percent_Identity=25.6281407035176, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43179; Mature: 43179

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKQNYYFQTDLILLFLGFVIISLLAIYNAQQIDQANTNFVIRQIAFFSIGVCFVAAIQ
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FIDLEQLYRGSIYIYIGGVLLLGLLLISPDAIAREINGANSWFTLPGLSIQPAEFAKMST
HHCHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHCCCCCCEEECCCCCCCCHHHHHHHH
ILFLAATITGHKEKTEVQTMKTDIMLLLKLIIYTMIPVGLIMLQPDFGTSMVYLFIAGMM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHH
IILSGINWRIIVSLIVGLVSLAGAAIGAIIRFPQFAIDVLGVAPYQVDRIMTWFDPSQQS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ADATFQFERSHMSLGSGQLFGKGMSSLEVQYPEAHTDFIFSVIGESFGFIGSAIVIFLYF
CCCEEEEEHHHHCCCCCCHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLYRLVTLGLSIYKHSPFGTYFCFGFLSLMLVHVFQNIGMTIGIMPITGIPLLLISYGG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
SSVMSTMLGLAVVYRVAVEHTIQNDYLFK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKKQNYYFQTDLILLFLGFVIISLLAIYNAQQIDQANTNFVIRQIAFFSIGVCFVAAIQ
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FIDLEQLYRGSIYIYIGGVLLLGLLLISPDAIAREINGANSWFTLPGLSIQPAEFAKMST
HHCHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHCCCCCCEEECCCCCCCCHHHHHHHH
ILFLAATITGHKEKTEVQTMKTDIMLLLKLIIYTMIPVGLIMLQPDFGTSMVYLFIAGMM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHH
IILSGINWRIIVSLIVGLVSLAGAAIGAIIRFPQFAIDVLGVAPYQVDRIMTWFDPSQQS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ADATFQFERSHMSLGSGQLFGKGMSSLEVQYPEAHTDFIFSVIGESFGFIGSAIVIFLYF
CCCEEEEEHHHHCCCCCCHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLYRLVTLGLSIYKHSPFGTYFCFGFLSLMLVHVFQNIGMTIGIMPITGIPLLLISYGG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
SSVMSTMLGLAVVYRVAVEHTIQNDYLFK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]