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The map label for this gene is katA [H]

Identifier: 23098088

GI number: 23098088

Start: 659805

End: 661268

Strand: Reverse

Name: katA [H]

Synonym: OB0633

Alternate gene names: 23098088

Gene position: 661268-659805 (Counterclockwise)

Preceding gene: 23098090

Following gene: 23098073

Centisome position: 18.21

GC content: 38.8

Gene sequence:

>1464_bases
TTGAGTAATAAAAGAAACACATTAACAACTGCTTCTGGAGCTCCAGTAGGCGATAACCAAAACTCAATTACAGCTGGTCA
TAACGGACCTACACTACTACAAGATTTTCATTTACTAGAAAAGCTTGCTCATTTTAATAGAGAACGTATCCCTGAGCGTG
TTGTACACGCAAAAGGTGCAGGTGCACATGGATACTTCGAAGTTACAAATGACGAAATATCTAAGTATACAAAAGCTGAT
TTCCTTAGTGAAAAAGGTAAACGCACGGATATGTTCATCCGCTTCTCTACAGTTGCTGGTGAGCAAGGTTCAGCAGATAC
TGTACGTGACCCTCGTGGTTTCGCGGTTAAATTTTATACTGAAGAAGGAAACTACGATTTAGTTGGTAACAATACACCTA
TCTTCTTCATTCGTGATGCGATTAAATTCCCAGATTTTATTCACACACAAAAACGTAATCCACAAACTCATTTAAAAGAT
AAAGACATGGTATGGGATTTCTGGTCATTATCTCCAGAATCATTACACCAAGTTACGTATCTTCATAGTGACCGTGGTCT
TCCAGCTACATTGCGTCACATGAACGGATATGGAAGTCATACGTTCAAATGGGTGAATGCAGAAGGAGAAGCATTCTGGG
TTAAATATCACTTTATTAGTGAACAAGGAATTAAAAACCTAGACCCTGCTCTAGCAGATAAAATTGCTGGTGAAAACCCA
GATTACCATACAGAAGATCTATTTAATGCAATCGAAGAAGGCGATCACCCTGCTTGGAAACTATATGTACAAATTATGCC
TTACGAAGATGCAAAAACGTACAAATGGGATCCATTTGATGTAACAAAAATCTGGTCTAAAAAAGACTACCCTCGTATTG
AAGTTGGACGCATGGTATTAGATCGTAATCCGGAGAACTACTTTGCAGAAGTAGAACAAGCTGCATTCTCTCCTGGTCAA
TTCGTACCTGGAATTGAAGCATCTCCAGATAAAATGCTTCAAGGTCGTTTATTCGGTTATTCTGATGCACATCGCTACCG
TCTAGGAGCAAACCATCATAGTATTCCAGTAAATCGTCCTAAAAACGAAGTAAATAATTATCAGCGTGATGGCTTTATGA
GCGTAGATGGTAATGGCGGTAACAAGCCAAATTATGAACCGAATAGCGTAAATGGCCCTACAGAAGATAGTGAAGCTAAA
ATCAATCCATTTGAAATTTATGGTCAAGCAGATAGTGTAACTTACGATAGTGATGATCACTATACTCAAGCAGGAGATCT
TTATCGACTTATGTCAGCAGATGAAAAAGATCGTCTAGTTGAAGCATTTGTAGGTCATATGACTCCAGTTACTAAAGATG
AAATTAAACTTCGTCAAATCGAGCATATCTATAAAGCAGACGCTGAATGGGGAGAGCGCGTAGCTCAAGGTCTTGGGTTA
CAAGTTCCAGAAAGCGTAAAATAA

Upstream 100 bases:

>100_bases
ATTTAAAATAATTGTAATTAAATATTGATTTTTATCTGGAGTATATTATAATATTAAGTGTAGAAGATTTAATACTTAAT
GAATAGAGAGGAGAATTACA

Downstream 100 bases:

>100_bases
TTCTTGATTAATAGTAAAGCATGGCTCTTGTTTTAAGAGCCATGCTTTTTATTTACCATCATTTCCAACCATCGTTAAGG
CAATTCTACCTTTTTGTACA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSNKRNTLTTASGAPVGDNQNSITAGHNGPTLLQDFHLLEKLAHFNRERIPERVVHAKGAGAHGYFEVTNDEISKYTKAD
FLSEKGKRTDMFIRFSTVAGEQGSADTVRDPRGFAVKFYTEEGNYDLVGNNTPIFFIRDAIKFPDFIHTQKRNPQTHLKD
KDMVWDFWSLSPESLHQVTYLHSDRGLPATLRHMNGYGSHTFKWVNAEGEAFWVKYHFISEQGIKNLDPALADKIAGENP
DYHTEDLFNAIEEGDHPAWKLYVQIMPYEDAKTYKWDPFDVTKIWSKKDYPRIEVGRMVLDRNPENYFAEVEQAAFSPGQ
FVPGIEASPDKMLQGRLFGYSDAHRYRLGANHHSIPVNRPKNEVNNYQRDGFMSVDGNGGNKPNYEPNSVNGPTEDSEAK
INPFEIYGQADSVTYDSDDHYTQAGDLYRLMSADEKDRLVEAFVGHMTPVTKDEIKLRQIEHIYKADAEWGERVAQGLGL
QVPESVK

Sequences:

>Translated_487_residues
MSNKRNTLTTASGAPVGDNQNSITAGHNGPTLLQDFHLLEKLAHFNRERIPERVVHAKGAGAHGYFEVTNDEISKYTKAD
FLSEKGKRTDMFIRFSTVAGEQGSADTVRDPRGFAVKFYTEEGNYDLVGNNTPIFFIRDAIKFPDFIHTQKRNPQTHLKD
KDMVWDFWSLSPESLHQVTYLHSDRGLPATLRHMNGYGSHTFKWVNAEGEAFWVKYHFISEQGIKNLDPALADKIAGENP
DYHTEDLFNAIEEGDHPAWKLYVQIMPYEDAKTYKWDPFDVTKIWSKKDYPRIEVGRMVLDRNPENYFAEVEQAAFSPGQ
FVPGIEASPDKMLQGRLFGYSDAHRYRLGANHHSIPVNRPKNEVNNYQRDGFMSVDGNGGNKPNYEPNSVNGPTEDSEAK
INPFEIYGQADSVTYDSDDHYTQAGDLYRLMSADEKDRLVEAFVGHMTPVTKDEIKLRQIEHIYKADAEWGERVAQGLGL
QVPESVK
>Mature_486_residues
SNKRNTLTTASGAPVGDNQNSITAGHNGPTLLQDFHLLEKLAHFNRERIPERVVHAKGAGAHGYFEVTNDEISKYTKADF
LSEKGKRTDMFIRFSTVAGEQGSADTVRDPRGFAVKFYTEEGNYDLVGNNTPIFFIRDAIKFPDFIHTQKRNPQTHLKDK
DMVWDFWSLSPESLHQVTYLHSDRGLPATLRHMNGYGSHTFKWVNAEGEAFWVKYHFISEQGIKNLDPALADKIAGENPD
YHTEDLFNAIEEGDHPAWKLYVQIMPYEDAKTYKWDPFDVTKIWSKKDYPRIEVGRMVLDRNPENYFAEVEQAAFSPGQF
VPGIEASPDKMLQGRLFGYSDAHRYRLGANHHSIPVNRPKNEVNNYQRDGFMSVDGNGGNKPNYEPNSVNGPTEDSEAKI
NPFEIYGQADSVTYDSDDHYTQAGDLYRLMSADEKDRLVEAFVGHMTPVTKDEIKLRQIEHIYKADAEWGERVAQGLGLQ
VPESVK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=448, Percent_Identity=59.375, Blast_Score=550, Evalue=1e-156,
Organism=Escherichia coli, GI48994891, Length=492, Percent_Identity=45.7317073170732, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=55.6025369978858, Blast_Score=534, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=53.0398322851153, Blast_Score=516, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI25151141, Length=473, Percent_Identity=53.276955602537, Blast_Score=514, Evalue=1e-146,
Organism=Saccharomyces cerevisiae, GI6320462, Length=435, Percent_Identity=50.5747126436782, Blast_Score=425, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321525, Length=516, Percent_Identity=40.5038759689922, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17981717, Length=478, Percent_Identity=55.4393305439331, Blast_Score=542, Evalue=1e-154,
Organism=Drosophila melanogaster, GI19920968, Length=486, Percent_Identity=48.3539094650206, Blast_Score=477, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55392; Mature: 55261

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKRNTLTTASGAPVGDNQNSITAGHNGPTLLQDFHLLEKLAHFNRERIPERVVHAKGA
CCCCCCEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
GAHGYFEVTNDEISKYTKADFLSEKGKRTDMFIRFSTVAGEQGSADTVRDPRGFAVKFYT
CCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEE
EEGNYDLVGNNTPIFFIRDAIKFPDFIHTQKRNPQTHLKDKDMVWDFWSLSPESLHQVTY
ECCCEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEHHCCCHHHHHHHHE
LHSDRGLPATLRHMNGYGSHTFKWVNAEGEAFWVKYHFISEQGIKNLDPALADKIAGENP
EECCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCC
DYHTEDLFNAIEEGDHPAWKLYVQIMPYEDAKTYKWDPFDVTKIWSKKDYPRIEVGRMVL
CCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCEECHHEE
DRNPENYFAEVEQAAFSPGQFVPGIEASPDKMLQGRLFGYSDAHRYRLGANHHSIPVNRP
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCEECCCCCCCCEEECCCCCCCCCCCC
KNEVNNYQRDGFMSVDGNGGNKPNYEPNSVNGPTEDSEAKINPFEIYGQADSVTYDSDDH
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCC
YTQAGDLYRLMSADEKDRLVEAFVGHMTPVTKDEIKLRQIEHIYKADAEWGERVAQGLGL
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
QVPESVK
CCCCCCC
>Mature Secondary Structure 
SNKRNTLTTASGAPVGDNQNSITAGHNGPTLLQDFHLLEKLAHFNRERIPERVVHAKGA
CCCCCEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
GAHGYFEVTNDEISKYTKADFLSEKGKRTDMFIRFSTVAGEQGSADTVRDPRGFAVKFYT
CCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEE
EEGNYDLVGNNTPIFFIRDAIKFPDFIHTQKRNPQTHLKDKDMVWDFWSLSPESLHQVTY
ECCCEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEHHCCCHHHHHHHHE
LHSDRGLPATLRHMNGYGSHTFKWVNAEGEAFWVKYHFISEQGIKNLDPALADKIAGENP
EECCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCC
DYHTEDLFNAIEEGDHPAWKLYVQIMPYEDAKTYKWDPFDVTKIWSKKDYPRIEVGRMVL
CCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCEECHHEE
DRNPENYFAEVEQAAFSPGQFVPGIEASPDKMLQGRLFGYSDAHRYRLGANHHSIPVNRP
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCEECCCCCCCCEEECCCCCCCCCCCC
KNEVNNYQRDGFMSVDGNGGNKPNYEPNSVNGPTEDSEAKINPFEIYGQADSVTYDSDDH
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCC
YTQAGDLYRLMSADEKDRLVEAFVGHMTPVTKDEIKLRQIEHIYKADAEWGERVAQGLGL
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
QVPESVK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1756979; 9202460; 9384377; 8180695; 10658653 [H]