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The map label for this gene is ndoA [H]

Identifier: 23098078

GI number: 23098078

Start: 651655

End: 652014

Strand: Direct

Name: ndoA [H]

Synonym: OB0623

Alternate gene names: 23098078

Gene position: 651655-652014 (Clockwise)

Preceding gene: 23098077

Following gene: 23098079

Centisome position: 17.95

GC content: 39.72

Gene sequence:

>360_bases
TTGATCGTTCAAAGAGGCGAGGTATATTTCGCTGACTTATCCCCTGTTGTTGGATCGGAGCAAGGTGGGGTAAGGCCTGT
CCTAATTCTCCAAAACGACATCGGTAACCGTTTCAGCCCTACTGTTATTGTCGCTGCGATAACAGCACAAATTCAAAAGG
CAAAATTACCAACCCATGTGGAGATTGATGCAAAGCGATATGGATTTGATCGGAATTCCGTAATTCTTTTGGAACAAATC
AGGACGTTGGATAAACAGCGTTTAACGGATAAAATTACGAAATTAGATAAGGAAATGATGATTAAAATTAATCAGGCATT
AGAAATAAGCCTCGGCTTAAAAGATGTATATGGTGGATAA

Upstream 100 bases:

>100_bases
GAAATGGGACGCATTAATTTGACGATTGCTTCTGAGGCCTTTCAAGCTGAAGAGGAGGCTGAAAACACCCTAGAGCGCTC
TGTGATCGGGGTGTAACAAT

Downstream 100 bases:

>100_bases
ACTCCTACTCTTTTTGAGTAAGGAGTTTTTTTGTCTATTTCTTTTAAGAAGGATGTCGATTATTATACGAAGCTATAAAT
GTTTTTAGGTACTGTATCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Endoribonuclease EndoA; Toxin EndoA [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MIVQRGEVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFDRNSVILLEQI
RTLDKQRLTDKITKLDKEMMIKINQALEISLGLKDVYGG

Sequences:

>Translated_119_residues
MIVQRGEVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFDRNSVILLEQI
RTLDKQRLTDKITKLDKEMMIKINQALEISLGLKDVYGG
>Mature_119_residues
MIVQRGEVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFDRNSVILLEQI
RTLDKQRLTDKITKLDKEMMIKINQALEISLGLKDVYGG

Specific function: Part of a toxin-antitoxin (TA) module. Has specificity for UAC sequences, yielding cleavage products with 3' phosphate and 5' hydroxyl groups. Overexpression is toxic for cell growth, probably by inhibiting protein synthesis through the cleavage of single

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003477
- InterPro:   IPR011067 [H]

Pfam domain/function: PF02452 PemK [H]

EC number: NA

Molecular weight: Translated: 13265; Mature: 13265

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVQRGEVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHV
CEEECCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCCCEE
EIDAKRYGFDRNSVILLEQIRTLDKQRLTDKITKLDKEMMIKINQALEISLGLKDVYGG
EECHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MIVQRGEVYFADLSPVVGSEQGGVRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHV
CEEECCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCCCEE
EIDAKRYGFDRNSVILLEQIRTLDKQRLTDKITKLDKEMMIKINQALEISLGLKDVYGG
EECHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]