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The map label for this gene is typA [H]

Identifier: 23098041

GI number: 23098041

Start: 612855

End: 614678

Strand: Direct

Name: typA [H]

Synonym: OB0586

Alternate gene names: 23098041

Gene position: 612855-614678 (Clockwise)

Preceding gene: 23098040

Following gene: 23098042

Centisome position: 16.88

GC content: 38.27

Gene sequence:

>1824_bases
ATGCAATTAAGAAATGATATTCGCAATATCGCAATTATTGCGCACGTTGACCACGGAAAAACAACGCTTGTGGATCAGCT
ATTAAAATATTCTGGTACTTTCCGAGACAATGAGCATGTTGATGAACGTGCAATGGACTCTGGAGATATAGAACGTGAAC
GTGGAATTACAATATTAGCTAAAAATACAGCTGTAAAATATAAAGATACAACGATAAATATATTAGATACACCTGGGCAC
GCTGACTTCGGTGGAGAAGTAGAACGTATCATGAAAATGGTAGATGGTGTTGCCTTAGTAGTAGATGCATATGAAGGTAC
AATGCCACAGACACGATTTGTGTTAAAGAAAGCATTGGAGCAAAAGTTAACACCGATGGTTGTGCTTAATAAAATTGATC
GCCCGAATGCACGCCCAGAAGAGGTTGTTGATGAAGTACTTGATTTATTTATTGAATTAGGAGCCGATGATGAACAATTA
GAATTTCCGGTAGTATATGCATCAGCTATTAATGGAACTTCTGGTTTAGAAGCGGAAGAGCAAGAAGAAACAATGGATCC
TGTATTCCAAACGATTTTAGAGCATATTCCAGCGCCAATTGATACAAAAGAAGAACCTTTACAATTCCAAGTAACACTAC
TTGATTATAACGACTATGTTGGACGTATTGGAGTGGGACGAGTTGTTCGAGGAAGCATAAAAGTTGGCCAGCAAGTGGTA
GTATTAAAACAAGATGGATCGCAAAAATCCTTCCGCGTTTCCAAGCTATTTGGTTTTACCGGGTTAAAACGTATTGAAAT
CCAAGAAGCTATAGCCGGTGATATCGTTGCGTTATCTGGAATGGAAGATTTAAATGTGGGAGAGACTGTATGCCCAGTAG
AGCAACCAGAAGCACTACCTTGGTTGCGAATTGATGAACCAACATTGCAAATGACATTCTTAGTAAATAATAGTCCTTTT
GCAGGTAAAGAAGGAAAGTTCATTACCTCTCGTAAAATTGAAGAACGTTTGATGAAGCAATTAGAGACAGATGTAAGCTT
GCGTGTAGACCCAACGGATTCGCCAGATGTATGGACAGTATCTGGACGTGGAGAATTACATCTATCAATCCTAATCGAAA
ACATGCGTCGTGAAGGTTATGAATTACAATTATCCAAACCGGAAGTTATTATTCGTGAAATTGATGGCGTGAAATGTGAA
CCAGTAGAACGTGTACAAGTGGATGTACCAGAAGAATACACGGGTGCAATTATGGAGTCACTAGGTGAACGTAAAGGTGA
AATGATTGATATGGTCAATCAAGGGAACGGTCAAGTTCGTATCGAATTTAAAGTGCCTTCTCGTGGATTATTAGGTTATA
CGACTGAATTCATGTCACAAACTCGTGGATACGGTATTTTAAATCACACGTTCGATGCTTACGAACCACTTATTAAAGGT
CAAGTCGGCGGACGTCGTGAAGGGGTACTAGTTGCACTTGAAAACGGGAAAGCATCAACTTACGGTATAATGAATCTAGA
AGATCGTGGTGTGATTTTTGTATCACCAGGAACAGAAGTATATGCAGGTATGATCGTAGGAGAACATAATCGTGATAATG
ACTTAACGGTTAATATTACACGTGAAAAACATTTAACCAATGTACGTTCAGCTACGAAAGATCAAACAACAACAATCCGT
AAGTCCAGAACTTTATCTTTAGAAGAAGCACTTCAATATTTAAGTGATGATGAATTTTGTGAAGTTACACCGGAATCCAT
TCGATTAAGAAAGAAAATCTTAAATAAAAATGAGAGAGAAAAAGCTGCAAAGCGTAAAGTATAA

Upstream 100 bases:

>100_bases
TAGAACGAAAATCACCACTGTAAGAAGTTTCACTTTATTTGAATGTATGATATAATTAATTGGTTATTCATTTTGAAGAT
GATAGAGGAGCGTAAAATTT

Downstream 100 bases:

>100_bases
TAATATTTTTAAAGCTGTAGAACTAGTTACTAAACTAGTTCTACAGCTTTTTTATAAGGTAGTCAATTTAATTTATAGAA
AGAAAATCGAAATAAGAGGT

Product: GTP-binding elongation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MQLRNDIRNIAIIAHVDHGKTTLVDQLLKYSGTFRDNEHVDERAMDSGDIERERGITILAKNTAVKYKDTTINILDTPGH
ADFGGEVERIMKMVDGVALVVDAYEGTMPQTRFVLKKALEQKLTPMVVLNKIDRPNARPEEVVDEVLDLFIELGADDEQL
EFPVVYASAINGTSGLEAEEQEETMDPVFQTILEHIPAPIDTKEEPLQFQVTLLDYNDYVGRIGVGRVVRGSIKVGQQVV
VLKQDGSQKSFRVSKLFGFTGLKRIEIQEAIAGDIVALSGMEDLNVGETVCPVEQPEALPWLRIDEPTLQMTFLVNNSPF
AGKEGKFITSRKIEERLMKQLETDVSLRVDPTDSPDVWTVSGRGELHLSILIENMRREGYELQLSKPEVIIREIDGVKCE
PVERVQVDVPEEYTGAIMESLGERKGEMIDMVNQGNGQVRIEFKVPSRGLLGYTTEFMSQTRGYGILNHTFDAYEPLIKG
QVGGRREGVLVALENGKASTYGIMNLEDRGVIFVSPGTEVYAGMIVGEHNRDNDLTVNITREKHLTNVRSATKDQTTTIR
KSRTLSLEEALQYLSDDEFCEVTPESIRLRKKILNKNEREKAAKRKV

Sequences:

>Translated_607_residues
MQLRNDIRNIAIIAHVDHGKTTLVDQLLKYSGTFRDNEHVDERAMDSGDIERERGITILAKNTAVKYKDTTINILDTPGH
ADFGGEVERIMKMVDGVALVVDAYEGTMPQTRFVLKKALEQKLTPMVVLNKIDRPNARPEEVVDEVLDLFIELGADDEQL
EFPVVYASAINGTSGLEAEEQEETMDPVFQTILEHIPAPIDTKEEPLQFQVTLLDYNDYVGRIGVGRVVRGSIKVGQQVV
VLKQDGSQKSFRVSKLFGFTGLKRIEIQEAIAGDIVALSGMEDLNVGETVCPVEQPEALPWLRIDEPTLQMTFLVNNSPF
AGKEGKFITSRKIEERLMKQLETDVSLRVDPTDSPDVWTVSGRGELHLSILIENMRREGYELQLSKPEVIIREIDGVKCE
PVERVQVDVPEEYTGAIMESLGERKGEMIDMVNQGNGQVRIEFKVPSRGLLGYTTEFMSQTRGYGILNHTFDAYEPLIKG
QVGGRREGVLVALENGKASTYGIMNLEDRGVIFVSPGTEVYAGMIVGEHNRDNDLTVNITREKHLTNVRSATKDQTTTIR
KSRTLSLEEALQYLSDDEFCEVTPESIRLRKKILNKNEREKAAKRKV
>Mature_607_residues
MQLRNDIRNIAIIAHVDHGKTTLVDQLLKYSGTFRDNEHVDERAMDSGDIERERGITILAKNTAVKYKDTTINILDTPGH
ADFGGEVERIMKMVDGVALVVDAYEGTMPQTRFVLKKALEQKLTPMVVLNKIDRPNARPEEVVDEVLDLFIELGADDEQL
EFPVVYASAINGTSGLEAEEQEETMDPVFQTILEHIPAPIDTKEEPLQFQVTLLDYNDYVGRIGVGRVVRGSIKVGQQVV
VLKQDGSQKSFRVSKLFGFTGLKRIEIQEAIAGDIVALSGMEDLNVGETVCPVEQPEALPWLRIDEPTLQMTFLVNNSPF
AGKEGKFITSRKIEERLMKQLETDVSLRVDPTDSPDVWTVSGRGELHLSILIENMRREGYELQLSKPEVIIREIDGVKCE
PVERVQVDVPEEYTGAIMESLGERKGEMIDMVNQGNGQVRIEFKVPSRGLLGYTTEFMSQTRGYGILNHTFDAYEPLIKG
QVGGRREGVLVALENGKASTYGIMNLEDRGVIFVSPGTEVYAGMIVGEHNRDNDLTVNITREKHLTNVRSATKDQTTTIR
KSRTLSLEEALQYLSDDEFCEVTPESIRLRKKILNKNEREKAAKRKV

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=546, Percent_Identity=27.1062271062271, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=43.609022556391, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=40, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=36, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI25306283, Length=177, Percent_Identity=35.5932203389831, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI19923640, Length=168, Percent_Identity=36.9047619047619, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI25306287, Length=168, Percent_Identity=36.9047619047619, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=41.4414414414414, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=41.4414414414414, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=41.4414414414414, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=38.0597014925373, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=38.0597014925373, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI34147630, Length=273, Percent_Identity=30.03663003663, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=31.7829457364341, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI53729339, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI53729337, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI48994988, Length=598, Percent_Identity=55.1839464882943, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=505, Percent_Identity=29.3069306930693, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1789738, Length=166, Percent_Identity=38.5542168674699, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790835, Length=182, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790412, Length=258, Percent_Identity=31.0077519379845, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789737, Length=258, Percent_Identity=31.0077519379845, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789559, Length=167, Percent_Identity=34.1317365269461, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=515, Percent_Identity=25.631067961165, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=42.9577464788732, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17533571, Length=172, Percent_Identity=37.7906976744186, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17506493, Length=164, Percent_Identity=34.1463414634146, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=128, Percent_Identity=35.9375, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=128, Percent_Identity=35.9375, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=140, Percent_Identity=35, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556456, Length=274, Percent_Identity=28.8321167883212, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25141371, Length=272, Percent_Identity=27.2058823529412, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994658, Length=156, Percent_Identity=35.2564102564103, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=511, Percent_Identity=27.7886497064579, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324707, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=181, Percent_Identity=34.2541436464088, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=154, Percent_Identity=37.012987012987, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=150, Percent_Identity=38, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324550, Length=147, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI78706572, Length=525, Percent_Identity=26.4761904761905, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=41.3793103448276, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=42.1428571428571, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357743, Length=188, Percent_Identity=37.2340425531915, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585709, Length=156, Percent_Identity=35.2564102564103, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585711, Length=156, Percent_Identity=35.2564102564103, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585713, Length=156, Percent_Identity=35.2564102564103, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221458488, Length=162, Percent_Identity=40.7407407407407, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363316, Length=303, Percent_Identity=30.03300330033, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17864358, Length=303, Percent_Identity=30.03300330033, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921738, Length=236, Percent_Identity=30.5084745762712, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28572034, Length=166, Percent_Identity=33.7349397590361, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68108; Mature: 68108

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRNDIRNIAIIAHVDHGKTTLVDQLLKYSGTFRDNEHVDERAMDSGDIERERGITILA
CCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHCCEEEEE
KNTAVKYKDTTINILDTPGHADFGGEVERIMKMVDGVALVVDAYEGTMPQTRFVLKKALE
ECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHH
QKLTPMVVLNKIDRPNARPEEVVDEVLDLFIELGADDEQLEFPVVYASAINGTSGLEAEE
HHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHH
QEETMDPVFQTILEHIPAPIDTKEEPLQFQVTLLDYNDYVGRIGVGRVVRGSIKVGQQVV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCEECCCEEE
VLKQDGSQKSFRVSKLFGFTGLKRIEIQEAIAGDIVALSGMEDLNVGETVCPVEQPEALP
EEECCCCCCCEEHHHHHCCCCCEEEEHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCCC
WLRIDEPTLQMTFLVNNSPFAGKEGKFITSRKIEERLMKQLETDVSLRVDPTDSPDVWTV
EEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
SGRGELHLSILIENMRREGYELQLSKPEVIIREIDGVKCEPVERVQVDVPEEYTGAIMES
CCCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHH
LGERKGEMIDMVNQGNGQVRIEFKVPSRGLLGYTTEFMSQTRGYGILNHTFDAYEPLIKG
HHHCCCCEEEHEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHCC
QVGGRREGVLVALENGKASTYGIMNLEDRGVIFVSPGTEVYAGMIVGEHNRDNDLTVNIT
CCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCEEEEEE
REKHLTNVRSATKDQTTTIRKSRTLSLEEALQYLSDDEFCEVTPESIRLRKKILNKNERE
HHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCHHH
KAAKRKV
HHHHCCC
>Mature Secondary Structure
MQLRNDIRNIAIIAHVDHGKTTLVDQLLKYSGTFRDNEHVDERAMDSGDIERERGITILA
CCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHCCEEEEE
KNTAVKYKDTTINILDTPGHADFGGEVERIMKMVDGVALVVDAYEGTMPQTRFVLKKALE
ECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHH
QKLTPMVVLNKIDRPNARPEEVVDEVLDLFIELGADDEQLEFPVVYASAINGTSGLEAEE
HHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHH
QEETMDPVFQTILEHIPAPIDTKEEPLQFQVTLLDYNDYVGRIGVGRVVRGSIKVGQQVV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCEECCCEEE
VLKQDGSQKSFRVSKLFGFTGLKRIEIQEAIAGDIVALSGMEDLNVGETVCPVEQPEALP
EEECCCCCCCEEHHHHHCCCCCEEEEHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCCC
WLRIDEPTLQMTFLVNNSPFAGKEGKFITSRKIEERLMKQLETDVSLRVDPTDSPDVWTV
EEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
SGRGELHLSILIENMRREGYELQLSKPEVIIREIDGVKCEPVERVQVDVPEEYTGAIMES
CCCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHH
LGERKGEMIDMVNQGNGQVRIEFKVPSRGLLGYTTEFMSQTRGYGILNHTFDAYEPLIKG
HHHCCCCEEEHEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHCC
QVGGRREGVLVALENGKASTYGIMNLEDRGVIFVSPGTEVYAGMIVGEHNRDNDLTVNIT
CCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCEEEEEE
REKHLTNVRSATKDQTTTIRKSRTLSLEEALQYLSDDEFCEVTPESIRLRKKILNKNERE
HHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCHHH
KAAKRKV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]