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The map label for this gene is cssR [H]

Identifier: 23098039

GI number: 23098039

Start: 610553

End: 611236

Strand: Direct

Name: cssR [H]

Synonym: OB0584

Alternate gene names: 23098039

Gene position: 610553-611236 (Clockwise)

Preceding gene: 23098037

Following gene: 23098040

Centisome position: 16.82

GC content: 35.09

Gene sequence:

>684_bases
ATGACAGTTCATATTGGTCTAGTTGAAGATGATACAAACATTCAGAATATCGTTTCCGCGTATTTAAAAAAGGAAGGATA
CCAAACTACAATTTTAGATAATGCGGAAGATGGTTGGAAACTTTGGGAGAACAACCCACCTGATATGTGGATATTAGATA
TAATGTTACCGGGAATGGACGGGTATGAATTTTGCAAAAAAATTCGAAATGAAAGTGATGTTCCGATTATCATTATTTCT
GCAAAAGATGAAGAAATTGACAAAATACTTGGGCTTGAATTAGGTGGAGATGATTATTTAACAAAGCCGTTTAGCCCTAG
AGAATTAATAGCTAGAGTGAAGAGATTATTTAAACGTTCAACCTCACACCGCCAAGATGAAATAGAAGAGGACCGTGTAA
AAGTTGATCAGCTGCTAGTTTATAAAAATGAACGTCGCGTATTTTTTGAAGGAGAAGAATTTGAAACAACAACAAAAGAG
TACGATATGCTGCTACTGCTTGCAGAAAACCCAAACAGAGCATTCTCAAGAGAAGAACTGCTTATGAAAATTTGGGGTAA
TGATTATTTTGGTAGTGATAGAGCAGTTGATGATTTAATTAAACGAATTCGTAAAAAAATGGGCAATATCCCACTAGAAA
CCGTATGGGGTTTTGGATATCGCTTAAGAAAAGATGAGGAATAA

Upstream 100 bases:

>100_bases
GTACAAATGTGGAAAAAATGTGTAATGATAACTTCGATTGTAATTTTCAAATGAATTATGTAAGAATATATATAACTATA
AAAGGAAAAGGTGAAGGTCA

Downstream 100 bases:

>100_bases
CAATGAAGCTTCAGTCGCAATTGAACGCAGCTTTCACAGCGTTGCTTTTAGTTATTATGACCACGGCGGGCTATATCATT
TATTCGTTGATTTTGGATTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTVHIGLVEDDTNIQNIVSAYLKKEGYQTTILDNAEDGWKLWENNPPDMWILDIMLPGMDGYEFCKKIRNESDVPIIIIS
AKDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRSTSHRQDEIEEDRVKVDQLLVYKNERRVFFEGEEFETTTKE
YDMLLLLAENPNRAFSREELLMKIWGNDYFGSDRAVDDLIKRIRKKMGNIPLETVWGFGYRLRKDEE

Sequences:

>Translated_227_residues
MTVHIGLVEDDTNIQNIVSAYLKKEGYQTTILDNAEDGWKLWENNPPDMWILDIMLPGMDGYEFCKKIRNESDVPIIIIS
AKDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRSTSHRQDEIEEDRVKVDQLLVYKNERRVFFEGEEFETTTKE
YDMLLLLAENPNRAFSREELLMKIWGNDYFGSDRAVDDLIKRIRKKMGNIPLETVWGFGYRLRKDEE
>Mature_226_residues
TVHIGLVEDDTNIQNIVSAYLKKEGYQTTILDNAEDGWKLWENNPPDMWILDIMLPGMDGYEFCKKIRNESDVPIIIISA
KDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRSTSHRQDEIEEDRVKVDQLLVYKNERRVFFEGEEFETTTKEY
DMLLLLAENPNRAFSREELLMKIWGNDYFGSDRAVDDLIKRIRKKMGNIPLETVWGFGYRLRKDEE

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.9344978165939, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=34.375, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.4978165938865, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=33.75, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=30.6666666666667, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=32.5892857142857, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.9285714285714, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=31.6742081447964, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=31.8181818181818, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=215, Percent_Identity=28.3720930232558, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=27.3972602739726, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.0076335877863, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26718; Mature: 26587

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHIGLVEDDTNIQNIVSAYLKKEGYQTTILDNAEDGWKLWENNPPDMWILDIMLPGMD
CEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCEEEEEEEECCCC
GYEFCKKIRNESDVPIIIISAKDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRS
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHHC
TSHRQDEIEEDRVKVDQLLVYKNERRVFFEGEEFETTTKEYDMLLLLAENPNRAFSREEL
CCCHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LMKIWGNDYFGSDRAVDDLIKRIRKKMGNIPLETVWGFGYRLRKDEE
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCCCC
>Mature Secondary Structure 
TVHIGLVEDDTNIQNIVSAYLKKEGYQTTILDNAEDGWKLWENNPPDMWILDIMLPGMD
EEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCCEEEEEEEECCCC
GYEFCKKIRNESDVPIIIISAKDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRS
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHHC
TSHRQDEIEEDRVKVDQLLVYKNERRVFFEGEEFETTTKEYDMLLLLAENPNRAFSREEL
CCCHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LMKIWGNDYFGSDRAVDDLIKRIRKKMGNIPLETVWGFGYRLRKDEE
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]