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The map label for this gene is yyxA [H]

Identifier: 23098038

GI number: 23098038

Start: 609005

End: 610390

Strand: Reverse

Name: yyxA [H]

Synonym: OB0583

Alternate gene names: 23098038

Gene position: 610390-609005 (Counterclockwise)

Preceding gene: 23098044

Following gene: 23098036

Centisome position: 16.81

GC content: 38.31

Gene sequence:

>1386_bases
ATGACTTATAGAGACAATAATAATGATGAAGAAAGAAATTTTCCAGAAGAGGAGAATAAAGAAAGTCCTTCAAATTTTGA
TCAAGAGCAACAAAATATAGAAAACGGGAATAGTGATGAAGGTCATTATGATGATTACTCATCATCACATTATGAGACAG
CTTCTACATTAGAAAACGATACTAGAAACCCCTCTACAACAAAAGCTACAAAAAACAAACAACGTGGAGGAGGTTGGTTA
CGAAGTTTTTCTGGAGGAGCCATTGGCGGGATTATCTCTTCACTTATTATCTTGATGTTAGTAGGTAACAATATACTTCC
TGCTTCAGATACTTCTGTCGAAAGTAATCAAGGTAATTCAGAGAGTAATAATGAATCATCTAATAATATTGTTCAGACTT
TAGCTTCTGATGATGCAGAAAAATCCACAAATATCGATGAAGTTTCCAAAGCTGTTGTTGGTGTAATTAATAAACAACAG
CAAAGTGTGTGGGAGAGCAGTCAAGAAGCCGGAACCGGTTCTGGTATTATCTATAAAAAAGAAAATGACGCGGCTTATGT
TGCAACCAATCAACATGTTGTTGATGGTGCAGAGGAAGTAGAAGTAGTTATCGATGAAGAGCATCGTGTTTCCGCGGAAG
TACTCGGCGTAGACTCTTTAAGTGACTTAGCCGTACTTAAGATAGATGGCGAGAATGTAGATACTGTAGCTAATTTCGGC
TCTAGTACCGATACTCAAGTTGGAGAAACAGTGCTTGCAATCGGAAATCCACTTGGGATGGAATTCGTAAATACAGTTAC
GAAAGGAATTATAAGTGGGTTAAATCGTTCTGTAGAAGTAGATACCAATAGTGATGGTAGAGCGGATTGGATTACCGAAG
TACTTCAAACGGATGCTGCGATAAACCCTGGAAACAGTGGTGGCGCGTTAGTTAATGAAAACGGAGATGTTATTGGCATC
AACTCCATGAAAATTGCTCAGAGTAGTGTCGAAGGAATCGGATTTGCCATTCCAGCAGATGAGGCTTTACCAATTATTGA
ACAGTTAGAAACGGAAGGCGAAGTGTCTCGTCCACTTATTGGAATTAGTACAGCTCCACTAAATCAAGTGCCTGCACAAT
ATCGTGCTGAGATAGATATTCCAGATGATATCAAAGGCGGAATGGTAATAGCAGATGTTCAAGCTGATTCACCAGCAGCC
AACGCTGGTCTGGAACAATTTGACGTAATTACAAAAATCAACGGTAATGAAGTAACGTCCATTATAGAATTACGTAAACA
TCTCTATGAGAATGGAGAAGCTGGAGAACATGTTAAAATCGAATATGTTCGTGATGGTGAAGTACATTCCATTACATTAA
AATTAGATGAATTTCAGGCAGAATAA

Upstream 100 bases:

>100_bases
ATCGAAGTTATCATTACACATTTTTTCCACATTTGTACCAAATGATTACCTTTCAAACCACCTATAATAAAGGTATCAAC
ATTCATTGGAGGTGCTTTAC

Downstream 100 bases:

>100_bases
ATCTTAAGCTTTTATTTTAAAAGAGGTTGGGACTGACAAAAGTTTTGTTCAAAAGACGGAAGGAAATCTAGCTTAAGCGC
AAGAAATTTACGGATAATCC

Product: serine protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTYRDNNNDEERNFPEEENKESPSNFDQEQQNIENGNSDEGHYDDYSSSHYETASTLENDTRNPSTTKATKNKQRGGGWL
RSFSGGAIGGIISSLIILMLVGNNILPASDTSVESNQGNSESNNESSNNIVQTLASDDAEKSTNIDEVSKAVVGVINKQQ
QSVWESSQEAGTGSGIIYKKENDAAYVATNQHVVDGAEEVEVVIDEEHRVSAEVLGVDSLSDLAVLKIDGENVDTVANFG
SSTDTQVGETVLAIGNPLGMEFVNTVTKGIISGLNRSVEVDTNSDGRADWITEVLQTDAAINPGNSGGALVNENGDVIGI
NSMKIAQSSVEGIGFAIPADEALPIIEQLETEGEVSRPLIGISTAPLNQVPAQYRAEIDIPDDIKGGMVIADVQADSPAA
NAGLEQFDVITKINGNEVTSIIELRKHLYENGEAGEHVKIEYVRDGEVHSITLKLDEFQAE

Sequences:

>Translated_461_residues
MTYRDNNNDEERNFPEEENKESPSNFDQEQQNIENGNSDEGHYDDYSSSHYETASTLENDTRNPSTTKATKNKQRGGGWL
RSFSGGAIGGIISSLIILMLVGNNILPASDTSVESNQGNSESNNESSNNIVQTLASDDAEKSTNIDEVSKAVVGVINKQQ
QSVWESSQEAGTGSGIIYKKENDAAYVATNQHVVDGAEEVEVVIDEEHRVSAEVLGVDSLSDLAVLKIDGENVDTVANFG
SSTDTQVGETVLAIGNPLGMEFVNTVTKGIISGLNRSVEVDTNSDGRADWITEVLQTDAAINPGNSGGALVNENGDVIGI
NSMKIAQSSVEGIGFAIPADEALPIIEQLETEGEVSRPLIGISTAPLNQVPAQYRAEIDIPDDIKGGMVIADVQADSPAA
NAGLEQFDVITKINGNEVTSIIELRKHLYENGEAGEHVKIEYVRDGEVHSITLKLDEFQAE
>Mature_460_residues
TYRDNNNDEERNFPEEENKESPSNFDQEQQNIENGNSDEGHYDDYSSSHYETASTLENDTRNPSTTKATKNKQRGGGWLR
SFSGGAIGGIISSLIILMLVGNNILPASDTSVESNQGNSESNNESSNNIVQTLASDDAEKSTNIDEVSKAVVGVINKQQQ
SVWESSQEAGTGSGIIYKKENDAAYVATNQHVVDGAEEVEVVIDEEHRVSAEVLGVDSLSDLAVLKIDGENVDTVANFGS
STDTQVGETVLAIGNPLGMEFVNTVTKGIISGLNRSVEVDTNSDGRADWITEVLQTDAAINPGNSGGALVNENGDVIGIN
SMKIAQSSVEGIGFAIPADEALPIIEQLETEGEVSRPLIGISTAPLNQVPAQYRAEIDIPDDIKGGMVIADVQADSPAAN
AGLEQFDVITKINGNEVTSIIELRKHLYENGEAGEHVKIEYVRDGEVHSITLKLDEFQAE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=264, Percent_Identity=34.0909090909091, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4506141, Length=286, Percent_Identity=33.9160839160839, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI22129776, Length=291, Percent_Identity=31.2714776632302, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI7019477, Length=250, Percent_Identity=35.2, Blast_Score=102, Evalue=9e-22,
Organism=Escherichia coli, GI1789629, Length=287, Percent_Identity=35.5400696864112, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786356, Length=286, Percent_Identity=36.7132867132867, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789630, Length=333, Percent_Identity=33.6336336336336, Blast_Score=146, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24646839, Length=294, Percent_Identity=32.6530612244898, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 49401; Mature: 49270

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRDNNNDEERNFPEEENKESPSNFDQEQQNIENGNSDEGHYDDYSSSHYETASTLEND
CCCCCCCCCHHCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCC
TRNPSTTKATKNKQRGGGWLRSFSGGAIGGIISSLIILMLVGNNILPASDTSVESNQGNS
CCCCCCCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ESNNESSNNIVQTLASDDAEKSTNIDEVSKAVVGVINKQQQSVWESSQEAGTGSGIIYKK
CCCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ENDAAYVATNQHVVDGAEEVEVVIDEEHRVSAEVLGVDSLSDLAVLKIDGENVDTVANFG
CCCEEEEEECCHHHCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCHHHHHCC
SSTDTQVGETVLAIGNPLGMEFVNTVTKGIISGLNRSVEVDTNSDGRADWITEVLQTDAA
CCCCCHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCC
INPGNSGGALVNENGDVIGINSMKIAQSSVEGIGFAIPADEALPIIEQLETEGEVSRPLI
CCCCCCCCEEECCCCCEEEECCHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCCCCCCEE
GISTAPLNQVPAQYRAEIDIPDDIKGGMVIADVQADSPAANAGLEQFDVITKINGNEVTS
EEECCCCHHCCHHHEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHEEEECCCHHHHH
IIELRKHLYENGEAGEHVKIEYVRDGEVHSITLKLDEFQAE
HHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEECCCCCC
>Mature Secondary Structure 
TYRDNNNDEERNFPEEENKESPSNFDQEQQNIENGNSDEGHYDDYSSSHYETASTLEND
CCCCCCCCHHCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCC
TRNPSTTKATKNKQRGGGWLRSFSGGAIGGIISSLIILMLVGNNILPASDTSVESNQGNS
CCCCCCCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ESNNESSNNIVQTLASDDAEKSTNIDEVSKAVVGVINKQQQSVWESSQEAGTGSGIIYKK
CCCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ENDAAYVATNQHVVDGAEEVEVVIDEEHRVSAEVLGVDSLSDLAVLKIDGENVDTVANFG
CCCEEEEEECCHHHCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCHHHHHCC
SSTDTQVGETVLAIGNPLGMEFVNTVTKGIISGLNRSVEVDTNSDGRADWITEVLQTDAA
CCCCCHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCC
INPGNSGGALVNENGDVIGINSMKIAQSSVEGIGFAIPADEALPIIEQLETEGEVSRPLI
CCCCCCCCEEECCCCCEEEECCHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCCCCCCEE
GISTAPLNQVPAQYRAEIDIPDDIKGGMVIADVQADSPAANAGLEQFDVITKINGNEVTS
EEECCCCHHCCHHHEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHEEEECCCHHHHH
IIELRKHLYENGEAGEHVKIEYVRDGEVHSITLKLDEFQAE
HHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]