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The map label for this gene is trpD

Identifier: 23097980

GI number: 23097980

Start: 557090

End: 558112

Strand: Reverse

Name: trpD

Synonym: OB0525

Alternate gene names: 23097980

Gene position: 558112-557090 (Counterclockwise)

Preceding gene: 23097981

Following gene: 23097979

Centisome position: 15.37

GC content: 36.95

Gene sequence:

>1023_bases
ATGAAGCACTCACTTCATAAAATTATTGAACGACAAGATTTATCCACAGAAGAAATAAAAGAAGTATTTAAACATTGTTT
CTCACAAGAAGTATCTGATTCGGAACTAGCAGCCATTCTTATCTCCTTAAAAATGAAAGGAGAAACCGCTGAGGAAGTAG
CTGGATTATCTCAAGTTATTCAAGAACATTCTCCTTTCCTACTAAACTTTCATCAACCAGTAATGGACAATTGCGGAACG
GGCGGAGATCGTTCTAATAGTTTTAATATCAGTACATGTTCTGCCTTTGTATTAGCTGGAGCTGGTGTCACCGTAGCAAA
GCATGGAAATAGAAGTGTATCTAGTCAAACAGGAAGTGCAGATGTCTTAGAGAAATTAGGCGTATCTCTTGCTTTTACTA
AAGAACAAGTGAATGAAATGTTAGATAAAAATCAAATTGCTTTCTTATTTGCTCAACATGTACATCCGACACTAAAGCAA
GTGGGCAAAGTAAGAAAAGATTTACGAATACCTACTATTTTTAATTTCATCGGCCCATTAACAAATCCTGTCCACTTAGA
TTCTCAATATATTGGAGTCTATGATCCAGAAGCTCTTCAAATGGTGGCAAAAGCTGCACAACTACTTGGAAGAGAACGAG
CAATTGTGATTCATGGGGCTGGCGGTTTAGACGAGGCTTCTTTACAAGGAGAAAATAAATATATCCTCGTAGAGAATGAT
CGTTTAGAAGAAAAAACCATTCATCCAGAAGAGGTGGGATTATCTGTTTATCCGAACGATGAAATTCAAGGAGGAAATGC
AACAGAAAACGCAAATATCTTACTTTCTGTATTAAAAGGGGAAGATAGTGCATATCTAGATACGGTATTGTTCAATGCAG
GTATTGCATTGTTTGCCAGCAAAAAAGCGGATTCCATTTATGACGGTGTCGAACTTGCTCGGGAAAGTATTACATCTGGA
TCAGCATTAAGCAAACTCAATAACTTAATCACATTCAGTAAGAAAGTTAGCGAGGTGGTTTAA

Upstream 100 bases:

>100_bases
GGAATGCAGTTTCACCCAGAATCAATCGGTACAAAGGATGGAAAGCAAATCATTAAGAATTTCTTAATCCAAATCAAAGC
CTTACAGGAGGATGAAAATA

Downstream 100 bases:

>100_bases
ATGACTTTTCTAGCAAAAATCTTAGAGGAAAAGCAAACGGAAGTTAACAGTAGAAAACAAGAGAAAATCGATTTCGGAAG
TAGAAATATACCAGTGCACT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKHSLHKIIERQDLSTEEIKEVFKHCFSQEVSDSELAAILISLKMKGETAEEVAGLSQVIQEHSPFLLNFHQPVMDNCGT
GGDRSNSFNISTCSAFVLAGAGVTVAKHGNRSVSSQTGSADVLEKLGVSLAFTKEQVNEMLDKNQIAFLFAQHVHPTLKQ
VGKVRKDLRIPTIFNFIGPLTNPVHLDSQYIGVYDPEALQMVAKAAQLLGRERAIVIHGAGGLDEASLQGENKYILVEND
RLEEKTIHPEEVGLSVYPNDEIQGGNATENANILLSVLKGEDSAYLDTVLFNAGIALFASKKADSIYDGVELARESITSG
SALSKLNNLITFSKKVSEVV

Sequences:

>Translated_340_residues
MKHSLHKIIERQDLSTEEIKEVFKHCFSQEVSDSELAAILISLKMKGETAEEVAGLSQVIQEHSPFLLNFHQPVMDNCGT
GGDRSNSFNISTCSAFVLAGAGVTVAKHGNRSVSSQTGSADVLEKLGVSLAFTKEQVNEMLDKNQIAFLFAQHVHPTLKQ
VGKVRKDLRIPTIFNFIGPLTNPVHLDSQYIGVYDPEALQMVAKAAQLLGRERAIVIHGAGGLDEASLQGENKYILVEND
RLEEKTIHPEEVGLSVYPNDEIQGGNATENANILLSVLKGEDSAYLDTVLFNAGIALFASKKADSIYDGVELARESITSG
SALSKLNNLITFSKKVSEVV
>Mature_340_residues
MKHSLHKIIERQDLSTEEIKEVFKHCFSQEVSDSELAAILISLKMKGETAEEVAGLSQVIQEHSPFLLNFHQPVMDNCGT
GGDRSNSFNISTCSAFVLAGAGVTVAKHGNRSVSSQTGSADVLEKLGVSLAFTKEQVNEMLDKNQIAFLFAQHVHPTLKQ
VGKVRKDLRIPTIFNFIGPLTNPVHLDSQYIGVYDPEALQMVAKAAQLLGRERAIVIHGAGGLDEASLQGENKYILVEND
RLEEKTIHPEEVGLSVYPNDEIQGGNATENANILLSVLKGEDSAYLDTVLFNAGIALFASKKADSIYDGVELARESITSG
SALSKLNNLITFSKKVSEVV

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=328, Percent_Identity=35.3658536585366, Blast_Score=184, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6320561, Length=272, Percent_Identity=34.9264705882353, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_OCEIH (Q8ESU1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691446.1
- ProteinModelPortal:   Q8ESU1
- SMR:   Q8ESU1
- GeneID:   1015795
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0525
- NMPDR:   fig|221109.1.peg.528
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- BioCyc:   OIHE221109:OB0525-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36948; Mature: 36948

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSLHKIIERQDLSTEEIKEVFKHCFSQEVSDSELAAILISLKMKGETAEEVAGLSQVI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHH
QEHSPFLLNFHQPVMDNCGTGGDRSNSFNISTCSAFVLAGAGVTVAKHGNRSVSSQTGSA
HHCCCEEEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH
DVLEKLGVSLAFTKEQVNEMLDKNQIAFLFAQHVHPTLKQVGKVRKDLRIPTIFNFIGPL
HHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCC
TNPVHLDSQYIGVYDPEALQMVAKAAQLLGRERAIVIHGAGGLDEASLQGENKYILVEND
CCCEEECCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECC
RLEEKTIHPEEVGLSVYPNDEIQGGNATENANILLSVLKGEDSAYLDTVLFNAGIALFAS
CCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHEEEC
KKADSIYDGVELARESITSGSALSKLNNLITFSKKVSEVV
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHSLHKIIERQDLSTEEIKEVFKHCFSQEVSDSELAAILISLKMKGETAEEVAGLSQVI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHH
QEHSPFLLNFHQPVMDNCGTGGDRSNSFNISTCSAFVLAGAGVTVAKHGNRSVSSQTGSA
HHCCCEEEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH
DVLEKLGVSLAFTKEQVNEMLDKNQIAFLFAQHVHPTLKQVGKVRKDLRIPTIFNFIGPL
HHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCC
TNPVHLDSQYIGVYDPEALQMVAKAAQLLGRERAIVIHGAGGLDEASLQGENKYILVEND
CCCEEECCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECC
RLEEKTIHPEEVGLSVYPNDEIQGGNATENANILLSVLKGEDSAYLDTVLFNAGIALFAS
CCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHEEEC
KKADSIYDGVELARESITSGSALSKLNNLITFSKKVSEVV
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376