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The map label for this gene is ydbM [H]

Identifier: 23097748

GI number: 23097748

Start: 327301

End: 328458

Strand: Reverse

Name: ydbM [H]

Synonym: OB0293

Alternate gene names: 23097748

Gene position: 328458-327301 (Counterclockwise)

Preceding gene: 23097751

Following gene: 23097746

Centisome position: 9.05

GC content: 39.03

Gene sequence:

>1158_bases
ATGAATAATTTACTCGAACTCAATACAACTGAAAAACGCATACAATTATTAAAAAATACTGTTGCGCCATTTAATGAACG
CGCACAAAAGCATGATAAAGACGTATCTTTTCCATTTGAAAACTATAAAGACTTACAATCAATTGGTTATCCTAGTTTGA
CCATACCAAAGGAATACGGAGGCGCCGGGATAACCTTAGATGAATTACTGACCTATCAAGAAATCATCGCACAGGCAGAT
GGCTCTACTGCTTTATCAATCGGTTGGCATATGGGGATTATGAAATATCTTGGTGAAAACAAAATATGGAATGAAGATGT
CTATTCCACTGTAGCAAATGATGTTATTCAAAACGGAGCTCTACTCAACAATGCAGCAACAGAACCAGCTACTGGCAGCC
CGACCAGAGGCGGTAAACCAGAGACACACGCGATTAAACAAGGTAACAAGTGGATAATGAATGGCAGAAAAACATTCACT
ACACTATCTCCAATTCTTACCTACTTTGTTGTTAGTGCAACTATTGATGAGACAGGTGAAGTCGGCAATTTCTTAATCAA
ACGAGATAGACCGGGCGTGAACGTAGAAGAGACGTGGGATTCTATTGCAATGCGTGGCAGCGGAAGTCACGATTTAGTAT
TAGAGAATGTTCACCTAGATGAAGAAAATTTAGTAGAGATATTATCAAACAAGAAAAGAAAACCAGCTGGTTGGTTACTT
CACATACCTGCCTGTTATCTAGGAATCGCACAGGCAGCGCAAAAAGAAGCGGTACAATTCGCCATGAATTATTCACCAAA
CAGTATTGAAGGAACTATATCTGATTTACCTAATGTAAAACAAAAGATGGGTGACCTTGAATTGTTATTAATGGAATCTA
AGCATTTCCTTCATTCCATTGCACAACAATGGGATAATGGCGATGAAAACATTCGTGTTGCGATGGGACCTGAACTTGGT
GCAGCAAAACTATCGGTTACTAATAAAGCTGTTCATGCCGTTGATTTAGCTATGCGGATTGTTGGAGCAAAAAGCTTATC
AGAGAAAAACAATCTACAACGCTACTATCGAGACGTTCGAGCGGGATTGCACAATCCTCCGATGGATGATATGACAATGA
TGCAATTAGCTGATAGATCAATGAAAGAGAATAACTAA

Upstream 100 bases:

>100_bases
TTCTTTTCAAATACCAGTTAATTGAATTTTATTTTTAACAATGAAATAATAAGAATTATACCTATTGACTTACTAGGCAT
TATAGAGGAGGTCCTAAATA

Downstream 100 bases:

>100_bases
TTCATATGTAACCTCCTATTTTCATAAAGTTCGTATTTGGACTTATTATGACTATAGGAGGTTGTTTTTCTTGAACAGAT
TTCATGTTATTCATTCAATA

Product: short-chain-specific acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNNLLELNTTEKRIQLLKNTVAPFNERAQKHDKDVSFPFENYKDLQSIGYPSLTIPKEYGGAGITLDELLTYQEIIAQAD
GSTALSIGWHMGIMKYLGENKIWNEDVYSTVANDVIQNGALLNNAATEPATGSPTRGGKPETHAIKQGNKWIMNGRKTFT
TLSPILTYFVVSATIDETGEVGNFLIKRDRPGVNVEETWDSIAMRGSGSHDLVLENVHLDEENLVEILSNKKRKPAGWLL
HIPACYLGIAQAAQKEAVQFAMNYSPNSIEGTISDLPNVKQKMGDLELLLMESKHFLHSIAQQWDNGDENIRVAMGPELG
AAKLSVTNKAVHAVDLAMRIVGAKSLSEKNNLQRYYRDVRAGLHNPPMDDMTMMQLADRSMKENN

Sequences:

>Translated_385_residues
MNNLLELNTTEKRIQLLKNTVAPFNERAQKHDKDVSFPFENYKDLQSIGYPSLTIPKEYGGAGITLDELLTYQEIIAQAD
GSTALSIGWHMGIMKYLGENKIWNEDVYSTVANDVIQNGALLNNAATEPATGSPTRGGKPETHAIKQGNKWIMNGRKTFT
TLSPILTYFVVSATIDETGEVGNFLIKRDRPGVNVEETWDSIAMRGSGSHDLVLENVHLDEENLVEILSNKKRKPAGWLL
HIPACYLGIAQAAQKEAVQFAMNYSPNSIEGTISDLPNVKQKMGDLELLLMESKHFLHSIAQQWDNGDENIRVAMGPELG
AAKLSVTNKAVHAVDLAMRIVGAKSLSEKNNLQRYYRDVRAGLHNPPMDDMTMMQLADRSMKENN
>Mature_385_residues
MNNLLELNTTEKRIQLLKNTVAPFNERAQKHDKDVSFPFENYKDLQSIGYPSLTIPKEYGGAGITLDELLTYQEIIAQAD
GSTALSIGWHMGIMKYLGENKIWNEDVYSTVANDVIQNGALLNNAATEPATGSPTRGGKPETHAIKQGNKWIMNGRKTFT
TLSPILTYFVVSATIDETGEVGNFLIKRDRPGVNVEETWDSIAMRGSGSHDLVLENVHLDEENLVEILSNKKRKPAGWLL
HIPACYLGIAQAAQKEAVQFAMNYSPNSIEGTISDLPNVKQKMGDLELLLMESKHFLHSIAQQWDNGDENIRVAMGPELG
AAKLSVTNKAVHAVDLAMRIVGAKSLSEKNNLQRYYRDVRAGLHNPPMDDMTMMQLADRSMKENN

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=362, Percent_Identity=24.8618784530387, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=23.6074270557029, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=23.7388724035608, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI21361497, Length=363, Percent_Identity=23.4159779614325, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=23.1182795698925, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=23.4042553191489, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=363, Percent_Identity=25.6198347107438, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=21.0810810810811, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=384, Percent_Identity=22.65625, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646207, Length=363, Percent_Identity=24.5179063360882, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355753, Length=367, Percent_Identity=23.9782016348774, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666513, Length=360, Percent_Identity=22.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=364, Percent_Identity=23.9010989010989, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363737, Length=395, Percent_Identity=21.5189873417722, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42782; Mature: 42782

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLLELNTTEKRIQLLKNTVAPFNERAQKHDKDVSFPFENYKDLQSIGYPSLTIPKEYG
CCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCHHCC
GAGITLDELLTYQEIIAQADGSTALSIGWHMGIMKYLGENKIWNEDVYSTVANDVIQNGA
CCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
LLNNAATEPATGSPTRGGKPETHAIKQGNKWIMNGRKTFTTLSPILTYFVVSATIDETGE
EECCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
VGNFLIKRDRPGVNVEETWDSIAMRGSGSHDLVLENVHLDEENLVEILSNKKRKPAGWLL
CCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEE
HIPACYLGIAQAAQKEAVQFAMNYSPNSIEGTISDLPNVKQKMGDLELLLMESKHFLHSI
EHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCHHEEHHHHHHHHHHH
AQQWDNGDENIRVAMGPELGAAKLSVTNKAVHAVDLAMRIVGAKSLSEKNNLQRYYRDVR
HHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLHNPPMDDMTMMQLADRSMKENN
HCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNLLELNTTEKRIQLLKNTVAPFNERAQKHDKDVSFPFENYKDLQSIGYPSLTIPKEYG
CCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCHHCC
GAGITLDELLTYQEIIAQADGSTALSIGWHMGIMKYLGENKIWNEDVYSTVANDVIQNGA
CCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
LLNNAATEPATGSPTRGGKPETHAIKQGNKWIMNGRKTFTTLSPILTYFVVSATIDETGE
EECCCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
VGNFLIKRDRPGVNVEETWDSIAMRGSGSHDLVLENVHLDEENLVEILSNKKRKPAGWLL
CCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEE
HIPACYLGIAQAAQKEAVQFAMNYSPNSIEGTISDLPNVKQKMGDLELLLMESKHFLHSI
EHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCHHEEHHHHHHHHHHH
AQQWDNGDENIRVAMGPELGAAKLSVTNKAVHAVDLAMRIVGAKSLSEKNNLQRYYRDVR
HHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLHNPPMDDMTMMQLADRSMKENN
HCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]