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The map label for this gene is glmM

Identifier: 23097687

GI number: 23097687

Start: 254122

End: 255462

Strand: Direct

Name: glmM

Synonym: OB0232

Alternate gene names: 23097687

Gene position: 254122-255462 (Clockwise)

Preceding gene: 23097686

Following gene: 23097688

Centisome position: 7.0

GC content: 39.75

Gene sequence:

>1341_bases
ATGGGTAAATTTTTTGGAACAGATGGCGTGAGAGGAGTAGCAAACGAAGGTCTAACACCTGAGCTTGCATTTAAGCTCGG
ACGTTTTGGTGGATATGTACTTACTAAAGATAGTGAAAGACCACGTATATTAATTGGACGAGACACACGTGTTTCTGGAC
ATATGCTAGAAGGTGCTCTTTTAGCTGGTCTGTTATCCATTGGTGCGGAGGTAATGCGATTAGGAGTCATTTCTACTCCA
GGGGTCGCGTATTTGACGAAGGCAACTAGTGCACAAGCTGGTGTGATGATTTCTGCTTCTCATAATCCAGTAGAAGACAA
TGGAATTAAATTCTTTGGGCCAGATGGCTTTAAACTAACAGACGCACAAGAAAATGAGATTGAATCGCTAATGGAGGGCG
AGGATAATTTACCTCGACCAACAGGAGCAGATATCGGGGTTGTCAATGATTACTTTGAAGGCGGACAGAAGTATTTATCT
TATCTTAAAGATACGATTGATAATGACTTCGAAGGAATTCATATTGCGATTGATTGTGCTAACGGCGCAACATCTAGTCT
GGCGACGCATCTTTTTGCTGACCTAGAAGCAGACATTTACTCTATTGGTTCATCTCCAGATGGATTAAATATAAATGATG
GTTTTGGATCTACGCATCCAGAGAAACTACAAGAATTCGTTGTAGAAAAAAATGCAGATATTGGTCTTGCTTTTGATGGA
GATGGAGATCGACTTATCGCTGTTGATGAAAAGGGTAATTTAGTTGATGGGGATAAAATCATGTTTATCTGTGCTAAGTA
CATGCATGAGATAGGGATGCTGCGAAAAGATACAGTGGTATCTACAGTAATGAGTAATCTCGGCTTTTACAAAGCGTTAG
AAAATATTGGTCTAAACAGTAATAAGACCTCTGTCGGTGACAGATATGTAATGGAAGAAATGCGCCAAAACGGATATAAC
TTGGGTGGCGAACAATCTGGTCATATAATATTCCTAGATTATATTACTACTGGTGACGGTATGTTATCAGCTATTCAACT
TGTTAATGTGATGCGTGAAACAGGAAAACCTTTATCCGAACTTGCTGATGAAATGGTTGTTTTCCCTCAAGTGTTAAAGA
ATGTTCGTGTAATGGATAAGAACCAAGCTTTAAGTAGCTCAGTTCTATTAGATGAAGTAGACGCAGTAGAAAAAGAACTT
GGTGAAGATGGTCGCGTGTTAGTTAGACCTTCTGGTACAGAACCATTAGTAAGAGTGATGGTGGAAGCCAAGACAAAAGA
AGAATGTGAACAATATGCTGACCGAATTGTCTCGGTAATTGAACAGCACTTAGGAGCATAG

Upstream 100 bases:

>100_bases
CAATCTGAGCAACCAGAACAGCCAGAACAATCTGAGGAAGATGAAGACCAAAATCAAGATTAACTAATGTATGTATTGGT
AACTAAAGGAGAGGTATTAA

Downstream 100 bases:

>100_bases
ATGAAAAAGACAGCGGAGAATGAATTCGCTGTCTTTTTTGTTTTTGGTCTTAGAAAACCCCTGGCTATGCCAGGGGTTCC
AGAAAGCTTCTAGCGTGGGG

Product: phosphoglucomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MGKFFGTDGVRGVANEGLTPELAFKLGRFGGYVLTKDSERPRILIGRDTRVSGHMLEGALLAGLLSIGAEVMRLGVISTP
GVAYLTKATSAQAGVMISASHNPVEDNGIKFFGPDGFKLTDAQENEIESLMEGEDNLPRPTGADIGVVNDYFEGGQKYLS
YLKDTIDNDFEGIHIAIDCANGATSSLATHLFADLEADIYSIGSSPDGLNINDGFGSTHPEKLQEFVVEKNADIGLAFDG
DGDRLIAVDEKGNLVDGDKIMFICAKYMHEIGMLRKDTVVSTVMSNLGFYKALENIGLNSNKTSVGDRYVMEEMRQNGYN
LGGEQSGHIIFLDYITTGDGMLSAIQLVNVMRETGKPLSELADEMVVFPQVLKNVRVMDKNQALSSSVLLDEVDAVEKEL
GEDGRVLVRPSGTEPLVRVMVEAKTKEECEQYADRIVSVIEQHLGA

Sequences:

>Translated_446_residues
MGKFFGTDGVRGVANEGLTPELAFKLGRFGGYVLTKDSERPRILIGRDTRVSGHMLEGALLAGLLSIGAEVMRLGVISTP
GVAYLTKATSAQAGVMISASHNPVEDNGIKFFGPDGFKLTDAQENEIESLMEGEDNLPRPTGADIGVVNDYFEGGQKYLS
YLKDTIDNDFEGIHIAIDCANGATSSLATHLFADLEADIYSIGSSPDGLNINDGFGSTHPEKLQEFVVEKNADIGLAFDG
DGDRLIAVDEKGNLVDGDKIMFICAKYMHEIGMLRKDTVVSTVMSNLGFYKALENIGLNSNKTSVGDRYVMEEMRQNGYN
LGGEQSGHIIFLDYITTGDGMLSAIQLVNVMRETGKPLSELADEMVVFPQVLKNVRVMDKNQALSSSVLLDEVDAVEKEL
GEDGRVLVRPSGTEPLVRVMVEAKTKEECEQYADRIVSVIEQHLGA
>Mature_445_residues
GKFFGTDGVRGVANEGLTPELAFKLGRFGGYVLTKDSERPRILIGRDTRVSGHMLEGALLAGLLSIGAEVMRLGVISTPG
VAYLTKATSAQAGVMISASHNPVEDNGIKFFGPDGFKLTDAQENEIESLMEGEDNLPRPTGADIGVVNDYFEGGQKYLSY
LKDTIDNDFEGIHIAIDCANGATSSLATHLFADLEADIYSIGSSPDGLNINDGFGSTHPEKLQEFVVEKNADIGLAFDGD
GDRLIAVDEKGNLVDGDKIMFICAKYMHEIGMLRKDTVVSTVMSNLGFYKALENIGLNSNKTSVGDRYVMEEMRQNGYNL
GGEQSGHIIFLDYITTGDGMLSAIQLVNVMRETGKPLSELADEMVVFPQVLKNVRVMDKNQALSSSVLLDEVDAVEKELG
EDGRVLVRPSGTEPLVRVMVEAKTKEECEQYADRIVSVIEQHLGA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=44.1704035874439, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1788361, Length=447, Percent_Identity=25.503355704698, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17864244, Length=368, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_OCEIH (Q8ETM7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691153.1
- ProteinModelPortal:   Q8ETM7
- SMR:   Q8ETM7
- GeneID:   1015394
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0232
- NMPDR:   fig|221109.1.peg.233
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- BioCyc:   OIHE221109:OB0232-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48293; Mature: 48162

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 100-100

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFFGTDGVRGVANEGLTPELAFKLGRFGGYVLTKDSERPRILIGRDTRVSGHMLEGAL
CCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHH
LAGLLSIGAEVMRLGVISTPGVAYLTKATSAQAGVMISASHNPVEDNGIKFFGPDGFKLT
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCEEEECCCCCEEC
DAQENEIESLMEGEDNLPRPTGADIGVVNDYFEGGQKYLSYLKDTIDNDFEGIHIAIDCA
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
NGATSSLATHLFADLEADIYSIGSSPDGLNINDGFGSTHPEKLQEFVVEKNADIGLAFDG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
DGDRLIAVDEKGNLVDGDKIMFICAKYMHEIGMLRKDTVVSTVMSNLGFYKALENIGLNS
CCCEEEEECCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NKTSVGDRYVMEEMRQNGYNLGGEQSGHIIFLDYITTGDGMLSAIQLVNVMRETGKPLSE
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCHHH
LADEMVVFPQVLKNVRVMDKNQALSSSVLLDEVDAVEKELGEDGRVLVRPSGTEPLVRVM
HHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
VEAKTKEECEQYADRIVSVIEQHLGA
HHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKFFGTDGVRGVANEGLTPELAFKLGRFGGYVLTKDSERPRILIGRDTRVSGHMLEGAL
CCCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHH
LAGLLSIGAEVMRLGVISTPGVAYLTKATSAQAGVMISASHNPVEDNGIKFFGPDGFKLT
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCEEEECCCCCEEC
DAQENEIESLMEGEDNLPRPTGADIGVVNDYFEGGQKYLSYLKDTIDNDFEGIHIAIDCA
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
NGATSSLATHLFADLEADIYSIGSSPDGLNINDGFGSTHPEKLQEFVVEKNADIGLAFDG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
DGDRLIAVDEKGNLVDGDKIMFICAKYMHEIGMLRKDTVVSTVMSNLGFYKALENIGLNS
CCCEEEEECCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NKTSVGDRYVMEEMRQNGYNLGGEQSGHIIFLDYITTGDGMLSAIQLVNVMRETGKPLSE
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCHHH
LADEMVVFPQVLKNVRVMDKNQALSSSVLLDEVDAVEKELGEDGRVLVRPSGTEPLVRVM
HHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
VEAKTKEECEQYADRIVSVIEQHLGA
HHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376