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The map label for this gene is yacO [H]

Identifier: 23097556

GI number: 23097556

Start: 121549

End: 122295

Strand: Direct

Name: yacO [H]

Synonym: OB0101

Alternate gene names: 23097556

Gene position: 121549-122295 (Clockwise)

Preceding gene: 23097555

Following gene: 23097557

Centisome position: 3.35

GC content: 41.23

Gene sequence:

>747_bases
GTGGACAATGAAGTCATTATGGGAAGGAATCCTGTTATGGAAGCTCTGAAATCTGGGCGGTCAGTAAATAAAGTGATGGT
TACAGAACAAATACAAGGTTCCACTTTTCAAAAAATTAACCAACTAGCAAGAGAGGCTGGAACAATTGTACAAAAAGTTC
CACGCTCTAAGTTAGATCAGATGGAATTAGGAAATCATCAAGGGGTGGTAGCATATGTAGCTTCGTATACGTACGCCTCG
TTAGACGATTTATTTGACCGAGCTAATGAACGTGGCGAGGATCCTTTCTTTATCTTATTAGATGAATTAGAAGATCCACA
CAATTTAGGCTCAATATTACGAAGCGCAGATGCGACAGGTGTACATGGAGTTATTATTCCTAAACGACGCTCAGTCGGAT
TAACCGCAACGGTTGCAAAAACTGCCGCTGGCGCGATAGAACATATCCCAGTTGTGCGAGTAACCAATATGTCTAATACT
ATTGATGAATTAAAAGAACGAAATGTTTGGATTGTTGGAACAGAAGCGGAAGCAGACCAAGACTATCGACAATTAGATGG
ATCATTACCTATTGGTATTGTAATTGGTAACGAAGGGAAAGGAATGAGTCGTCTCGTTCGAAAAAAATGTGACTGGACAG
TGGGCTTACCTATGGTCGGACAAGTATCCTCACTCAATGCATCGGTAGCTTGCGGACTTTTGCTTTATGAAGTATACCGT
AAACGTCATCCTCTCGGAGATCAGTAA

Upstream 100 bases:

>100_bases
GAGGCACTTATTGGGTATCACTATATGATGAAAAACGAGGATCGATTAGAAGAACTTATTCAAAATGCAATTCAGTACGC
GGAAGAAAGGAGAGATAGCC

Downstream 100 bases:

>100_bases
TGAAAGAAGTCTTGATTGTTGATGGATATAATGTAATTGGAGCTTGGGGAGAATTGCAACGATTGAAAGAGAAAGAAATT
GGACAGGCAAGAGATCGACT

Product: tRNA:rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MDNEVIMGRNPVMEALKSGRSVNKVMVTEQIQGSTFQKINQLAREAGTIVQKVPRSKLDQMELGNHQGVVAYVASYTYAS
LDDLFDRANERGEDPFFILLDELEDPHNLGSILRSADATGVHGVIIPKRRSVGLTATVAKTAAGAIEHIPVVRVTNMSNT
IDELKERNVWIVGTEAEADQDYRQLDGSLPIGIVIGNEGKGMSRLVRKKCDWTVGLPMVGQVSSLNASVACGLLLYEVYR
KRHPLGDQ

Sequences:

>Translated_248_residues
MDNEVIMGRNPVMEALKSGRSVNKVMVTEQIQGSTFQKINQLAREAGTIVQKVPRSKLDQMELGNHQGVVAYVASYTYAS
LDDLFDRANERGEDPFFILLDELEDPHNLGSILRSADATGVHGVIIPKRRSVGLTATVAKTAAGAIEHIPVVRVTNMSNT
IDELKERNVWIVGTEAEADQDYRQLDGSLPIGIVIGNEGKGMSRLVRKKCDWTVGLPMVGQVSSLNASVACGLLLYEVYR
KRHPLGDQ
>Mature_248_residues
MDNEVIMGRNPVMEALKSGRSVNKVMVTEQIQGSTFQKINQLAREAGTIVQKVPRSKLDQMELGNHQGVVAYVASYTYAS
LDDLFDRANERGEDPFFILLDELEDPHNLGSILRSADATGVHGVIIPKRRSVGLTATVAKTAAGAIEHIPVVRVTNMSNT
IDELKERNVWIVGTEAEADQDYRQLDGSLPIGIVIGNEGKGMSRLVRKKCDWTVGLPMVGQVSSLNASVACGLLLYEVYR
KRHPLGDQ

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=262, Percent_Identity=29.3893129770992, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1790623, Length=200, Percent_Identity=46.5, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1790083, Length=172, Percent_Identity=31.9767441860465, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788935, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555908, Length=258, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=31.5151515151515, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27200; Mature: 27200

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNEVIMGRNPVMEALKSGRSVNKVMVTEQIQGSTFQKINQLAREAGTIVQKVPRSKLDQ
CCCCEEECCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
MELGNHQGVVAYVASYTYASLDDLFDRANERGEDPFFILLDELEDPHNLGSILRSADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
VHGVIIPKRRSVGLTATVAKTAAGAIEHIPVVRVTNMSNTIDELKERNVWIVGTEAEADQ
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEEEEECCCCCHH
DYRQLDGSLPIGIVIGNEGKGMSRLVRKKCDWTVGLPMVGQVSSLNASVACGLLLYEVYR
HHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCEECCCCCCCHHHCCHHHHHHHHHHHHHH
KRHPLGDQ
HCCCCCCC
>Mature Secondary Structure
MDNEVIMGRNPVMEALKSGRSVNKVMVTEQIQGSTFQKINQLAREAGTIVQKVPRSKLDQ
CCCCEEECCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
MELGNHQGVVAYVASYTYASLDDLFDRANERGEDPFFILLDELEDPHNLGSILRSADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
VHGVIIPKRRSVGLTATVAKTAAGAIEHIPVVRVTNMSNTIDELKERNVWIVGTEAEADQ
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEEEEECCCCCHH
DYRQLDGSLPIGIVIGNEGKGMSRLVRKKCDWTVGLPMVGQVSSLNASVACGLLLYEVYR
HHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCEECCCCCCCHHHCCHHHHHHHHHHHHHH
KRHPLGDQ
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]