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The map label for this gene is ponA [H]

Identifier: 229918740

GI number: 229918740

Start: 2986042

End: 2988666

Strand: Direct

Name: ponA [H]

Synonym: EAT1b_3028

Alternate gene names: 229918740

Gene position: 2986042-2988666 (Clockwise)

Preceding gene: 229918739

Following gene: 229918741

Centisome position: 99.54

GC content: 45.45

Gene sequence:

>2625_bases
ATGGAGCGAAGTAGGGTCGCACGTCGACAAGATTCGACGACGAATAAACGCAAAAAAACTGGGAAACAACCAAAGACGAA
AAGTAAGAAACCGATGTGGAAACGCATCTTTTTATTAGGCTTCATGTTATTTATTGCTGCGGTAATCGCATTCGGCGCCT
ATACGGTATATGCCATTGCGACGGCACCAGAACTAGATGAAGACAAACTTGTCGATACGTATCCGATTCAGTTGCTTTCG
GCTGAAGGAGAACCGCTCGAAGGGGCGGGTCAGATTCGAGAGTATGTCTCCATCGACGACATCTCTGAAGTGATGCAACA
AGCGGTCGTGTCAATCGAAGACCGTCGTTTCTATGAGCATAACGGGATTGACTTACGTCGAATCGGCGGAGCCGTCGTTG
CCAACTTGACAGACGGTTTCGGTGCAGAAGGTGGATCGACCATCACACAACAATTGGTCAAGCAGTCGTTTCTTTCGACA
GATAAGAAGTTAAAACGTAAGCTTCAAGAACAATGGCTCGCACTCAAACTCGAGCGTGAGTATACGAAAGAACAGATTTT
AGAGATGTACTTGAACAAAAACTATTATGGTAGTGGTGGATACGGTGTGCAAACCGCATCGAAACGTTACTTCAATAAGC
CGGTCTCTGAGGTCAATTATCAAGAGGCCGCGATTCTCGCAGGTCTCCCGCAACGTCCAAGTGCCTACGATCCAATCAAT
GGTGATCAGGAGTTGACCCGCTACCGTCAAGAGCAAGTCTTGTCTGCGATGAAACGTGACGGACATATTTCTGAGGAGCA
GTACAATGAGGCACTTGATGTCTCCATTGCTGACGTCATCTCACCAGGTGAAGAGACGGAAGAAGAAGCGTTCACACGTG
CGATTTACTCTCGTGTATTGAATGAGTTAGAAGAGGACTATGGTCTTGAACAGTCAGATATTTACGGGACTGGTTTGAAA
GTTTATACGTCAATCAACAAAGAGTTACACACAAAAATCAACAGTGATATTAAATCGAATAATGTTAATTTACAAACAAG
TAGTTTCCCTGAAGATTTACGAATGGGTGCAACCGTCTTGAATACAAAGACCGGTGAAATTGTCGCTATCGTAGACAGTC
AACAGGCGAAGCAAGGTGATACCACATATCGTGACTACTCAAATGAAAAGTATCAAATCGGATCGACAGCTAAACCATTT
TTCGATTATGGTCCTGGAATTGAAAATGGGCAGTGGTCGACAGGTAAAGTGTTGCTTGACGCTAAATTAGATGGCACATA
TAGTCCGAATAACTATTATTCAGGTTTCCGTGGACCAAATACGATGCGCCAATACTTGAAAATTTCAGCGAACACGCCAG
CAGTTCGTGCTTTCCAAGAAGTGCGGGATGAGTATGGACAAGAAGCAATCGAATCGTTCGTTAAAAATGTAGGAATCGAA
CCTTCATATTCTGGCGATGAACTCAACGAATCTAATGCTTTAGGTACGGCAGAAGCGAGCACGACACAGATGGCTGCAGC
TTATGCAACACTTGGTGCGAATGGGATGTATACAAAACCGCACTTGATTCAAAAAATTGAATTCAATGATGGTTCAAGTA
TTAATTCACCGATTAAAGCCAAGCAAGCAATGGAAGATTATACAGCGTATATGTTGACAGACATGCTTCGTGATGTTGTG
AGTGCTGAAGGTGGAACTTATGTACCTGGCGCGTTCCCATGGGACGTAGCAGGTAAAACGGGTACGACGAACGAGCCTAA
CTCTACAAATCCGAAAGATAAATGGTTTACCGGTTATTCTACGGATTACTCGATCTCAGTATGGACAGGAAAAACGAAAG
ATTCGACAGTCGCTTCGTTCGATCCAGACTATGCCCAATACTATTTCGAGTATATGATGCAACAAGTGACGAATGCGACG
GGACAACCGGATCGATTCCAACGTCCGGACTCAGTCTTATCACTTGGCAATGAACTCTATGTAAAAGGGACAAAACCAAA
AGATCTTCAACCTGAGAAGTTGGTTGCTCCGACTGGGGCAAGTGTCAACTATGACGAAGAAGCCCAAACCGGTTCTGTCT
CATGGTCATACGATTTCGATGGTGCACAAGCAGATGGCTATACGGATGTCACGTTCACAGTGACACAGAAGTCAGCTGAC
GGAAGTGAGCAAGTCGTCGGAACGACCGGGGAGACGAGTGTAAATATTGCAAACTTGGCCGAAGGAGACACAACGTTTAC
CATTGTCGCGAATGCAACGAACCCGTTGACGGGTGAGCAGCAATCAGCACCGGCGCAAGCGAGCTACTCAATCGAACCGA
AAGAAGAGCCAAAGGAAGAAGAGGAAAACCCTTCTGACGAGGAAAATTCCGAAGATGAACCATCAGACGAAAATAACGGG
AACGGGAATGAAAACGGAAATGGTAATGGTAACGGAGGCGGAAACGGCGAAGATACCACCGACGAACAAACTCCTGATGA
ACCGGCGACGGATGAAGGTTCTGGCGAAGGAACAGACGAACCAACTGACGGAGATGATTCAGGAACTCCGTTAGAGGGAC
AATCCAATGGTGAATCGTCTGACACGAATCGTGGAAATGGCAATTCAAACAATGGGAATAACTAA

Upstream 100 bases:

>100_bases
AAAAGGAAGCGATTGAAGTTCCGACGAGAGCCTTGCCGTCGATTGATTATTTGACGGTGCTCGATCAATGGCTCGATTGA
ATAGAAGGAGTGAACCATGA

Downstream 100 bases:

>100_bases
GGAAAGCAGGGCGACATTGTGCGCCCTGTTTTTCGTTTGACTTTGCTATAATGAAAAGAAAGGGAACAGGATGGTGACAC
ATGGTTCAACTCTCTTTAAA

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: PBP1; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MERSRVARRQDSTTNKRKKTGKQPKTKSKKPMWKRIFLLGFMLFIAAVIAFGAYTVYAIATAPELDEDKLVDTYPIQLLS
AEGEPLEGAGQIREYVSIDDISEVMQQAVVSIEDRRFYEHNGIDLRRIGGAVVANLTDGFGAEGGSTITQQLVKQSFLST
DKKLKRKLQEQWLALKLEREYTKEQILEMYLNKNYYGSGGYGVQTASKRYFNKPVSEVNYQEAAILAGLPQRPSAYDPIN
GDQELTRYRQEQVLSAMKRDGHISEEQYNEALDVSIADVISPGEETEEEAFTRAIYSRVLNELEEDYGLEQSDIYGTGLK
VYTSINKELHTKINSDIKSNNVNLQTSSFPEDLRMGATVLNTKTGEIVAIVDSQQAKQGDTTYRDYSNEKYQIGSTAKPF
FDYGPGIENGQWSTGKVLLDAKLDGTYSPNNYYSGFRGPNTMRQYLKISANTPAVRAFQEVRDEYGQEAIESFVKNVGIE
PSYSGDELNESNALGTAEASTTQMAAAYATLGANGMYTKPHLIQKIEFNDGSSINSPIKAKQAMEDYTAYMLTDMLRDVV
SAEGGTYVPGAFPWDVAGKTGTTNEPNSTNPKDKWFTGYSTDYSISVWTGKTKDSTVASFDPDYAQYYFEYMMQQVTNAT
GQPDRFQRPDSVLSLGNELYVKGTKPKDLQPEKLVAPTGASVNYDEEAQTGSVSWSYDFDGAQADGYTDVTFTVTQKSAD
GSEQVVGTTGETSVNIANLAEGDTTFTIVANATNPLTGEQQSAPAQASYSIEPKEEPKEEEENPSDEENSEDEPSDENNG
NGNENGNGNGNGGGNGEDTTDEQTPDEPATDEGSGEGTDEPTDGDDSGTPLEGQSNGESSDTNRGNGNSNNGNN

Sequences:

>Translated_874_residues
MERSRVARRQDSTTNKRKKTGKQPKTKSKKPMWKRIFLLGFMLFIAAVIAFGAYTVYAIATAPELDEDKLVDTYPIQLLS
AEGEPLEGAGQIREYVSIDDISEVMQQAVVSIEDRRFYEHNGIDLRRIGGAVVANLTDGFGAEGGSTITQQLVKQSFLST
DKKLKRKLQEQWLALKLEREYTKEQILEMYLNKNYYGSGGYGVQTASKRYFNKPVSEVNYQEAAILAGLPQRPSAYDPIN
GDQELTRYRQEQVLSAMKRDGHISEEQYNEALDVSIADVISPGEETEEEAFTRAIYSRVLNELEEDYGLEQSDIYGTGLK
VYTSINKELHTKINSDIKSNNVNLQTSSFPEDLRMGATVLNTKTGEIVAIVDSQQAKQGDTTYRDYSNEKYQIGSTAKPF
FDYGPGIENGQWSTGKVLLDAKLDGTYSPNNYYSGFRGPNTMRQYLKISANTPAVRAFQEVRDEYGQEAIESFVKNVGIE
PSYSGDELNESNALGTAEASTTQMAAAYATLGANGMYTKPHLIQKIEFNDGSSINSPIKAKQAMEDYTAYMLTDMLRDVV
SAEGGTYVPGAFPWDVAGKTGTTNEPNSTNPKDKWFTGYSTDYSISVWTGKTKDSTVASFDPDYAQYYFEYMMQQVTNAT
GQPDRFQRPDSVLSLGNELYVKGTKPKDLQPEKLVAPTGASVNYDEEAQTGSVSWSYDFDGAQADGYTDVTFTVTQKSAD
GSEQVVGTTGETSVNIANLAEGDTTFTIVANATNPLTGEQQSAPAQASYSIEPKEEPKEEEENPSDEENSEDEPSDENNG
NGNENGNGNGNGGGNGEDTTDEQTPDEPATDEGSGEGTDEPTDGDDSGTPLEGQSNGESSDTNRGNGNSNNGNN
>Mature_874_residues
MERSRVARRQDSTTNKRKKTGKQPKTKSKKPMWKRIFLLGFMLFIAAVIAFGAYTVYAIATAPELDEDKLVDTYPIQLLS
AEGEPLEGAGQIREYVSIDDISEVMQQAVVSIEDRRFYEHNGIDLRRIGGAVVANLTDGFGAEGGSTITQQLVKQSFLST
DKKLKRKLQEQWLALKLEREYTKEQILEMYLNKNYYGSGGYGVQTASKRYFNKPVSEVNYQEAAILAGLPQRPSAYDPIN
GDQELTRYRQEQVLSAMKRDGHISEEQYNEALDVSIADVISPGEETEEEAFTRAIYSRVLNELEEDYGLEQSDIYGTGLK
VYTSINKELHTKINSDIKSNNVNLQTSSFPEDLRMGATVLNTKTGEIVAIVDSQQAKQGDTTYRDYSNEKYQIGSTAKPF
FDYGPGIENGQWSTGKVLLDAKLDGTYSPNNYYSGFRGPNTMRQYLKISANTPAVRAFQEVRDEYGQEAIESFVKNVGIE
PSYSGDELNESNALGTAEASTTQMAAAYATLGANGMYTKPHLIQKIEFNDGSSINSPIKAKQAMEDYTAYMLTDMLRDVV
SAEGGTYVPGAFPWDVAGKTGTTNEPNSTNPKDKWFTGYSTDYSISVWTGKTKDSTVASFDPDYAQYYFEYMMQQVTNAT
GQPDRFQRPDSVLSLGNELYVKGTKPKDLQPEKLVAPTGASVNYDEEAQTGSVSWSYDFDGAQADGYTDVTFTVTQKSAD
GSEQVVGTTGETSVNIANLAEGDTTFTIVANATNPLTGEQQSAPAQASYSIEPKEEPKEEEENPSDEENSEDEPSDENNG
NGNENGNGNGNGGGNGEDTTDEQTPDEPATDEGSGEGTDEPTDGDDSGTPLEGQSNGESSDTNRGNGNSNNGNN

Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=Probably found all over the whole cell at low concentrations. Also localizes to the division site in vegetative cells [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fibronectin type-III domain [H]

Homologues:

Organism=Escherichia coli, GI1788867, Length=603, Percent_Identity=27.5290215588723, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87082258, Length=313, Percent_Identity=34.185303514377, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI1786343, Length=585, Percent_Identity=26.4957264957265, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1789601, Length=168, Percent_Identity=36.9047619047619, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001264
- InterPro:   IPR013783
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00041 fn3; PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 95887; Mature: 95887

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSRVARRQDSTTNKRKKTGKQPKTKSKKPMWKRIFLLGFMLFIAAVIAFGAYTVYAIA
CCHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TAPELDEDKLVDTYPIQLLSAEGEPLEGAGQIREYVSIDDISEVMQQAVVSIEDRRFYEH
ECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
NGIDLRRIGGAVVANLTDGFGAEGGSTITQQLVKQSFLSTDKKLKRKLQEQWLALKLERE
CCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTKEQILEMYLNKNYYGSGGYGVQTASKRYFNKPVSEVNYQEAAILAGLPQRPSAYDPIN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHCCHHHHHHHHCCCCCCCCCCCCC
GDQELTRYRQEQVLSAMKRDGHISEEQYNEALDVSIADVISPGEETEEEAFTRAIYSRVL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
NELEEDYGLEQSDIYGTGLKVYTSINKELHTKINSDIKSNNVNLQTSSFPEDLRMGATVL
HHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCEE
NTKTGEIVAIVDSQQAKQGDTTYRDYSNEKYQIGSTAKPFFDYGPGIENGQWSTGKVLLD
ECCCCCEEEEECCCCCCCCCCCHHCCCCCCEECCCCCCCHHHCCCCCCCCCCCCCCEEEE
AKLDGTYSPNNYYSGFRGPNTMRQYLKISANTPAVRAFQEVRDEYGQEAIESFVKNVGIE
EECCCCCCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYSGDELNESNALGTAEASTTQMAAAYATLGANGMYTKPHLIQKIEFNDGSSINSPIKA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCCCCCCCCHHH
KQAMEDYTAYMLTDMLRDVVSAEGGTYVPGAFPWDVAGKTGTTNEPNSTNPKDKWFTGYS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TDYSISVWTGKTKDSTVASFDPDYAQYYFEYMMQQVTNATGQPDRFQRPDSVLSLGNELY
CCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHCCCEEE
VKGTKPKDLQPEKLVAPTGASVNYDEEAQTGSVSWSYDFDGAQADGYTDVTFTVTQKSAD
EECCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCC
GSEQVVGTTGETSVNIANLAEGDTTFTIVANATNPLTGEQQSAPAQASYSIEPKEEPKEE
CCCCEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENPSDEENSEDEPSDENNGNGNENGNGNGNGGGNGEDTTDEQTPDEPATDEGSGEGTDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTDGDDSGTPLEGQSNGESSDTNRGNGNSNNGNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MERSRVARRQDSTTNKRKKTGKQPKTKSKKPMWKRIFLLGFMLFIAAVIAFGAYTVYAIA
CCHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TAPELDEDKLVDTYPIQLLSAEGEPLEGAGQIREYVSIDDISEVMQQAVVSIEDRRFYEH
ECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
NGIDLRRIGGAVVANLTDGFGAEGGSTITQQLVKQSFLSTDKKLKRKLQEQWLALKLERE
CCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTKEQILEMYLNKNYYGSGGYGVQTASKRYFNKPVSEVNYQEAAILAGLPQRPSAYDPIN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHCCHHHHHHHHCCCCCCCCCCCCC
GDQELTRYRQEQVLSAMKRDGHISEEQYNEALDVSIADVISPGEETEEEAFTRAIYSRVL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
NELEEDYGLEQSDIYGTGLKVYTSINKELHTKINSDIKSNNVNLQTSSFPEDLRMGATVL
HHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCEE
NTKTGEIVAIVDSQQAKQGDTTYRDYSNEKYQIGSTAKPFFDYGPGIENGQWSTGKVLLD
ECCCCCEEEEECCCCCCCCCCCHHCCCCCCEECCCCCCCHHHCCCCCCCCCCCCCCEEEE
AKLDGTYSPNNYYSGFRGPNTMRQYLKISANTPAVRAFQEVRDEYGQEAIESFVKNVGIE
EECCCCCCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYSGDELNESNALGTAEASTTQMAAAYATLGANGMYTKPHLIQKIEFNDGSSINSPIKA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCCCCCCCCHHH
KQAMEDYTAYMLTDMLRDVVSAEGGTYVPGAFPWDVAGKTGTTNEPNSTNPKDKWFTGYS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TDYSISVWTGKTKDSTVASFDPDYAQYYFEYMMQQVTNATGQPDRFQRPDSVLSLGNELY
CCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHCCCEEE
VKGTKPKDLQPEKLVAPTGASVNYDEEAQTGSVSWSYDFDGAQADGYTDVTFTVTQKSAD
EECCCCCCCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCC
GSEQVVGTTGETSVNIANLAEGDTTFTIVANATNPLTGEQQSAPAQASYSIEPKEEPKEE
CCCCEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENPSDEENSEDEPSDENNGNGNENGNGNGNGGGNGEDTTDEQTPDEPATDEGSGEGTDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTDGDDSGTPLEGQSNGESSDTNRGNGNSNNGNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7814321; 8760912; 9384377; 9721295; 10322023 [H]