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The map label for this gene is aroB

Identifier: 229918712

GI number: 229918712

Start: 2960029

End: 2961084

Strand: Direct

Name: aroB

Synonym: EAT1b_2999

Alternate gene names: 229918712

Gene position: 2960029-2961084 (Clockwise)

Preceding gene: 229918711

Following gene: 229918713

Centisome position: 98.67

GC content: 50.28

Gene sequence:

>1056_bases
ATGGTAACGATTCCAATCTCAGCATCGACCCCATACGACGTCGTCTTGGACAATCAGGATCGTTGGATCGATTCGGTTGA
TTGGTCAAGGTATTCGATGCTATGGGTCGTTACGGATAAACATGTCGAGTCTCTTTATGGAGAGTCGTTCCGTTCTACGT
TGAAACTGACCCATCCTCACGTCGTCTCGTCCGTCGTCGAAGCGGGTGATGCGTCGAAATCGCTATCTCAGCTCGAGCAG
CTTGTCGCAGAAGGGTTGCGCCATGGATGTGACCGCGAGACGTTGATTGTCGCCTTTGGTGGTGGGATGATTGGCGACTT
GGCTGGCTTTTTAGCAAGTGTCTACATGCGAGGCGTTCCATACATACAAGTGCCGACGACGATTTTGGCTCACGATTCGG
CTGTCGGAGGCAAAGTGGCAGTCAATCACCCCCTTGCGAAAAATGCGATTGGTTCGTTCTATCAGCCATCAGGCGTTTAT
TACAACGTCACTCGACTGAACACCTTGTCCGTACAGGAAGTGCGAAGCGGTCTCGGTGAGTTATTGAAACATGCGTACTT
ATCACGTTACGTCCTCGAATCCTCTTTCGAGGACGACTTGTTTTTAGACTTGAACGAGAACGAACCATTGGATTGGGTGT
CGTGGCTTGCTCGTGGGATTCGAGTGAAACAAGCCATCGTCGAGACGGACGAGCGAGAACAGGGCATTCGTGCTTGGCTC
AACTTTGGGCATACGTTCGGTCATGCCCTTGAGTCGGTGGAAGCCTATCGGATCCCACATGGAGAAGCGGTTTTACATGG
GATGGTGTTCGCTTTTCTCGTGTCTGGAGATGAAGTTCGAGCGATGCGGTTGTTCGATTGGATGCGTTCAAATGACGTCA
CGCCAATCGATTGGCAACCATTCGACCGCTACGTGGAAAAAATGATTCGGGATAAAAAGAACCGTCACGGTGCAATTCGT
TTTGTGTTACTTCGTGAAACGATCACCGTTGAGTCGGTACAGCTCGAACATCTTCAACAGACGTTTGAACAGATGAAAGG
ATGGTGGGAACGATGA

Upstream 100 bases:

>100_bases
TCGCATTTGAAATCGCGAAGGAAATGTGTGAGACGTTCGGGCACGACACGATGGAACGAATCAAACATCGGGTCGATGAG
TATCGGGAGGAGTTACGAGT

Downstream 100 bases:

>100_bases
GTTTAAACGGTTCTATCCGTGTACCGAGTGATAAATCCATCACACATCGGGCATTATTATTCGGGATGATGGCGAACGGG
ACGACGCACGTGCGGAATCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MVTIPISASTPYDVVLDNQDRWIDSVDWSRYSMLWVVTDKHVESLYGESFRSTLKLTHPHVVSSVVEAGDASKSLSQLEQ
LVAEGLRHGCDRETLIVAFGGGMIGDLAGFLASVYMRGVPYIQVPTTILAHDSAVGGKVAVNHPLAKNAIGSFYQPSGVY
YNVTRLNTLSVQEVRSGLGELLKHAYLSRYVLESSFEDDLFLDLNENEPLDWVSWLARGIRVKQAIVETDEREQGIRAWL
NFGHTFGHALESVEAYRIPHGEAVLHGMVFAFLVSGDEVRAMRLFDWMRSNDVTPIDWQPFDRYVEKMIRDKKNRHGAIR
FVLLRETITVESVQLEHLQQTFEQMKGWWER

Sequences:

>Translated_351_residues
MVTIPISASTPYDVVLDNQDRWIDSVDWSRYSMLWVVTDKHVESLYGESFRSTLKLTHPHVVSSVVEAGDASKSLSQLEQ
LVAEGLRHGCDRETLIVAFGGGMIGDLAGFLASVYMRGVPYIQVPTTILAHDSAVGGKVAVNHPLAKNAIGSFYQPSGVY
YNVTRLNTLSVQEVRSGLGELLKHAYLSRYVLESSFEDDLFLDLNENEPLDWVSWLARGIRVKQAIVETDEREQGIRAWL
NFGHTFGHALESVEAYRIPHGEAVLHGMVFAFLVSGDEVRAMRLFDWMRSNDVTPIDWQPFDRYVEKMIRDKKNRHGAIR
FVLLRETITVESVQLEHLQQTFEQMKGWWER
>Mature_351_residues
MVTIPISASTPYDVVLDNQDRWIDSVDWSRYSMLWVVTDKHVESLYGESFRSTLKLTHPHVVSSVVEAGDASKSLSQLEQ
LVAEGLRHGCDRETLIVAFGGGMIGDLAGFLASVYMRGVPYIQVPTTILAHDSAVGGKVAVNHPLAKNAIGSFYQPSGVY
YNVTRLNTLSVQEVRSGLGELLKHAYLSRYVLESSFEDDLFLDLNENEPLDWVSWLARGIRVKQAIVETDEREQGIRAWL
NFGHTFGHALESVEAYRIPHGEAVLHGMVFAFLVSGDEVRAMRLFDWMRSNDVTPIDWQPFDRYVEKMIRDKKNRHGAIR
FVLLRETITVESVQLEHLQQTFEQMKGWWER

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=300, Percent_Identity=38, Blast_Score=169, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320332, Length=315, Percent_Identity=34.6031746031746, Blast_Score=156, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_EXISA (C4L6N4)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887358.1
- GeneID:   7868603
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2999
- OMA:   GHALETY
- ProtClustDB:   CLSK2489437
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39886; Mature: 39886

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIPISASTPYDVVLDNQDRWIDSVDWSRYSMLWVVTDKHVESLYGESFRSTLKLTHPH
CEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCHH
VVSSVVEAGDASKSLSQLEQLVAEGLRHGCDRETLIVAFGGGMIGDLAGFLASVYMRGVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
YIQVPTTILAHDSAVGGKVAVNHPLAKNAIGSFYQPSGVYYNVTRLNTLSVQEVRSGLGE
EEEECCEEEECCCCCCCEEEECCCHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LLKHAYLSRYVLESSFEDDLFLDLNENEPLDWVSWLARGIRVKQAIVETDEREQGIRAWL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NFGHTFGHALESVEAYRIPHGEAVLHGMVFAFLVSGDEVRAMRLFDWMRSNDVTPIDWQP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCH
FDRYVEKMIRDKKNRHGAIRFVLLRETITVESVQLEHLQQTFEQMKGWWER
HHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTIPISASTPYDVVLDNQDRWIDSVDWSRYSMLWVVTDKHVESLYGESFRSTLKLTHPH
CEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCHH
VVSSVVEAGDASKSLSQLEQLVAEGLRHGCDRETLIVAFGGGMIGDLAGFLASVYMRGVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
YIQVPTTILAHDSAVGGKVAVNHPLAKNAIGSFYQPSGVYYNVTRLNTLSVQEVRSGLGE
EEEECCEEEECCCCCCCEEEECCCHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LLKHAYLSRYVLESSFEDDLFLDLNENEPLDWVSWLARGIRVKQAIVETDEREQGIRAWL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NFGHTFGHALESVEAYRIPHGEAVLHGMVFAFLVSGDEVRAMRLFDWMRSNDVTPIDWQP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCH
FDRYVEKMIRDKKNRHGAIRFVLLRETITVESVQLEHLQQTFEQMKGWWER
HHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA