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The map label for this gene is aroC

Identifier: 229918711

GI number: 229918711

Start: 2958872

End: 2960035

Strand: Direct

Name: aroC

Synonym: EAT1b_2998

Alternate gene names: 229918711

Gene position: 2958872-2960035 (Clockwise)

Preceding gene: 229918710

Following gene: 229918712

Centisome position: 98.63

GC content: 52.58

Gene sequence:

>1164_bases
ATGCGTTATTTGACAGCTGGTGAATCACATGGTCCCGGTCTGACGGTCATCATTGAAGGGGCCCCAGCCGGACTCGCGAT
CGATATTTCGCAAATCAATGCGGAGTTAAAAAAACGTCAATCTGGTTACGGTAGAGGGCGCCGCATGCAAATCGAGTCAG
ACCAAGTAGAAGTTCGTTCGGGAATACGGCATGGTGTGACCACAGGTGCACCCATCACTTTTTGGATTGAGAATAAAGAC
CATACGCATTGGAAACACGTCATGCAGGCGGAACCGATTGAAAGCGACATCGAAGTGAAACGCCGCGTCTCTCGGCCGAG
ACCTGGACATGCTGACCTGGTCGGTGGGATGAAGTATGACCATCGAGACTTACGTGACGTGTTGGAGCGTTCGAGCGCTA
GGGAAACAGCGGCTCGTGTCGCGGTCGGGGCTTTCTGTAAGCAGCTCCTTCAACAAGTCGGGGTGTCCCTCTTTAGTTAT
GTCAAAGTGATTGGTGGGGAACGGGCGGAGTCGCGTACATTCGATTCACTTCAAGAAGCCCAAGCGGTCGTCGATGCGTC
ACCGGTTCGTACGTTAGATGAAGCGGCCGCGTTGCGGATGATGCGTCGCATCGATGAGGCCAAGGCAAATGGAGACTCGA
TCGGTGGGATCGTGTGTACAGAAGTACATGGTGTTGTACCGGGACTTGGCTCGTATGTGCAGTACGACCGTAAACTGGAT
GCGAAAATCGCACAAGCGGTCATGAGTGTCAACGCATTTAAAGGTGTTGAATTCGGTGAAGGGTTCGAAATGGCGTATCG
TCCGGGTTCTGAAGTGATGGACCCGATCGCATACGGGGATAATGGATATACGCGACTCAGTAACCATCTCGGTGGATTTG
AAGGGGGCATGACAACGGGGATGCCGATCCTTTGTTCAGCCGTCATGAAGCCCATTCCGACCCTCTATAAACCCTTACAA
TCGGTCGATATTGATACGAAAGAGGCATTTTTGGCTCAAATCGAGCGGAGTGACTCGTGCGCCGTGCCTGCCGCTTCCCT
CGTCGTTGAGGCAGTCATCGCATTTGAAATCGCGAAGGAAATGTGTGAGACGTTCGGGCACGACACGATGGAACGAATCA
AACATCGGGTCGATGAGTATCGGGAGGAGTTACGAGTATGGTAA

Upstream 100 bases:

>100_bases
ATTTGTCGGTGGAACGGAACAAATTTTCCAACCGAAGCGTTATGGCTACGCAATGAAGCAAAGTTTCTTTTATGAAAAAA
TAGATGGATGAGGTGATCGG

Downstream 100 bases:

>100_bases
CGATTCCAATCTCAGCATCGACCCCATACGACGTCGTCTTGGACAATCAGGATCGTTGGATCGATTCGGTTGATTGGTCA
AGGTATTCGATGCTATGGGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRSGIRHGVTTGAPITFWIENKD
HTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYDHRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSY
VKVIGGERAESRTFDSLQEAQAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLD
AKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTGMPILCSAVMKPIPTLYKPLQ
SVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKEMCETFGHDTMERIKHRVDEYREELRVW

Sequences:

>Translated_387_residues
MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRSGIRHGVTTGAPITFWIENKD
HTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYDHRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSY
VKVIGGERAESRTFDSLQEAQAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLD
AKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTGMPILCSAVMKPIPTLYKPLQ
SVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKEMCETFGHDTMERIKHRVDEYREELRVW
>Mature_387_residues
MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRSGIRHGVTTGAPITFWIENKD
HTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYDHRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSY
VKVIGGERAESRTFDSLQEAQAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLD
AKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTGMPILCSAVMKPIPTLYKPLQ
SVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKEMCETFGHDTMERIKHRVDEYREELRVW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=34.453781512605, Blast_Score=147, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321290, Length=388, Percent_Identity=31.701030927835, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_EXISA (C4L6N3)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887357.1
- ProteinModelPortal:   C4L6N3
- GeneID:   7868602
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2998
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42596; Mature: 42596

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRS
CCCCCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
GIRHGVTTGAPITFWIENKDHTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYD
HHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCC
HRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSYVKVIGGERAESRTFDSLQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCCCCHHHHHHHHHHH
AKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTG
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC
MPILCSAVMKPIPTLYKPLQSVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
MCETFGHDTMERIKHRVDEYREELRVW
HHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRS
CCCCCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
GIRHGVTTGAPITFWIENKDHTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYD
HHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCC
HRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSYVKVIGGERAESRTFDSLQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCCCCHHHHHHHHHHH
AKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTG
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC
MPILCSAVMKPIPTLYKPLQSVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
MCETFGHDTMERIKHRVDEYREELRVW
HHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA