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The map label for this gene is hup [H]

Identifier: 229918705

GI number: 229918705

Start: 2954812

End: 2955084

Strand: Direct

Name: hup [H]

Synonym: EAT1b_2992

Alternate gene names: 229918705

Gene position: 2954812-2955084 (Clockwise)

Preceding gene: 229918704

Following gene: 229918706

Centisome position: 98.5

GC content: 41.39

Gene sequence:

>273_bases
ATGAACAAAACTGAATTGATCCAAGCTGTTACTGAGAAAGCCGATGTTTCTAAAAAAGAAGCAACGAAAATCGTAGAAGC
TACGTTTGAATCAATCACTGAAGCACTCCAAAACGGTGAGAAAATTCAATTGATCGGTTTTGGTACTTTTGAAGTTCGTG
AGCGTGCTGCCCGTAAAGGTCGTAACCCACGTACAAAAGAAGATATCGAAATCCCAGCGAGCAAAGTTCCTGCATTTAAA
GCAGGTAAAGCGCTCAAGGATGCGGTCAAGTAA

Upstream 100 bases:

>100_bases
GATAGTGAATGTCGCGAAATCATGCAAAAAATGTTGTCATATCAACGTTTGTACGATATGATTAATCCCGTAAACTCCCT
GTGAGAGGAGGTGAATCGTG

Downstream 100 bases:

>100_bases
TCTGCAATACATAAGTCGCCGAAAGGCGGCTTTTTTGTTGGGTTTGCGAGTTCGAATGACGTGAATGTGACAAAAATGTG
CTATACTATGTCAGAATGAC

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKTELIQAVTEKADVSKKEATKIVEATFESITEALQNGEKIQLIGFGTFEVRERAARKGRNPRTKEDIEIPASKVPAFK
AGKALKDAVK

Sequences:

>Translated_90_residues
MNKTELIQAVTEKADVSKKEATKIVEATFESITEALQNGEKIQLIGFGTFEVRERAARKGRNPRTKEDIEIPASKVPAFK
AGKALKDAVK
>Mature_90_residues
MNKTELIQAVTEKADVSKKEATKIVEATFESITEALQNGEKIQLIGFGTFEVRERAARKGRNPRTKEDIEIPASKVPAFK
AGKALKDAVK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=56.6666666666667, Blast_Score=108, Evalue=7e-26,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=55.0561797752809, Blast_Score=107, Evalue=2e-25,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=43.8202247191011, Blast_Score=83, Evalue=4e-18,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=38.6363636363636, Blast_Score=71, Evalue=1e-14,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9916; Mature: 9916

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTELIQAVTEKADVSKKEATKIVEATFESITEALQNGEKIQLIGFGTFEVRERAARKG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
RNPRTKEDIEIPASKVPAFKAGKALKDAVK
CCCCCCCCCCCCHHHCCCHHCCHHHHHHCC
>Mature Secondary Structure
MNKTELIQAVTEKADVSKKEATKIVEATFESITEALQNGEKIQLIGFGTFEVRERAARKG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
RNPRTKEDIEIPASKVPAFKAGKALKDAVK
CCCCCCCCCCCCHHHCCCHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]