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The map label for this gene is gpsA

Identifier: 229918702

GI number: 229918702

Start: 2952664

End: 2953689

Strand: Direct

Name: gpsA

Synonym: EAT1b_2989

Alternate gene names: 229918702

Gene position: 2952664-2953689 (Clockwise)

Preceding gene: 229918701

Following gene: 229918703

Centisome position: 98.43

GC content: 52.05

Gene sequence:

>1026_bases
ATGGCAAACGTAGCTGTCATCGGAGCAGGGAGCTGGGGAACGGCCATCTCGCTCGTGTTAGCAGATAATGGCCATGATGT
CCTGCTCTATGGACGTGAACAAGAACATGTGGATGAAATCAACTCGTCACATACGAACTCGTTTTATTTGAAAGACGCGC
CATTACCTGAATCCATTCGTGCGACGACGAACTTGAAAGAGGCGTTAGACGGTCGAAGTATCGTCTTTCTCGTCGTCCCG
AGTTCGGCGATTCGTCCTGTCTCGAAGGAATTGAACACATTGTTGACGGAACCTGTCACCATCGTTCATGCCGCGAAGGG
GATCGAACCGAAAACGCATGAGCGTCTTTCAGAAATCATCGCCGAAGAAATCGAACCGGCTAAACGTCGGGCAATCGGTG
TATTGACAGGACCGACTCATGCTGAAGAGGTTGCGGTCCGGAAACCGACGACCATCACGATCGCATGTGCTGACCTTGAT
GTCGCGGATGAAGTGCAGGAGCTCCTCACAAACGATCAGTTCCGTGTGTACTTGAATTCTGACGTCGTTGGGGCCGAGTA
CGGCGGAGCATTGAAAAATATCATTGCTCTAGCGGCAGGTATGACGGATGGACTCGGTTATGGGGACAATGCGAAAGCTG
CCCTCATGACTCGTGGGATTGTAGAAATTGCGCGACTTGGCGTGAAGCTTGGAGCGAACCCGGCCTCGTTCTCAGGATTG
ACAGGAATCGGAGACTTGATTGTGACAGCGACGTCACAACATAGCCGTAACTGGCGAGCCGGTAACGCCATCGGGCGTGG
TGAAAAGTTAGAAGACGTTCTCGGGAACATGGGAATGGTCGTCGAGGGCGTCCGCGCCTGTGAAGCGGCCCACTCCCTTG
CGAAAGAGGCGGGTGTGGAGATGCCGATCACAGAGGCGCTCTATAACGTGTTGTTTGAAGGGAAGAGTCCTCATGATGAA
GTGAAGAAATTAATGAGACGCCCGCAAAAACACGAGATGGAACAAGTTTTCCATTTTGAAGAATAG

Upstream 100 bases:

>100_bases
AACGTTATTTAGAGAATCAAATCCGTAAAGCATTTGACTTCACCGGGACACCGATTCACATCGTGGCTCGTCAGAAAAAC
TAATAACGGGGGTGCCACTT

Downstream 100 bases:

>100_bases
ACAGATTGAGAGAGGAGCTGACGTTTTCGTTCAGTTCCTCGCTTTTTTTTGCTAAACTTGAATTCTGGAGAACATAGAGA
AAGTAGGGGGATAGATGTGA

Product: Glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MANVAVIGAGSWGTAISLVLADNGHDVLLYGREQEHVDEINSSHTNSFYLKDAPLPESIRATTNLKEALDGRSIVFLVVP
SSAIRPVSKELNTLLTEPVTIVHAAKGIEPKTHERLSEIIAEEIEPAKRRAIGVLTGPTHAEEVAVRKPTTITIACADLD
VADEVQELLTNDQFRVYLNSDVVGAEYGGALKNIIALAAGMTDGLGYGDNAKAALMTRGIVEIARLGVKLGANPASFSGL
TGIGDLIVTATSQHSRNWRAGNAIGRGEKLEDVLGNMGMVVEGVRACEAAHSLAKEAGVEMPITEALYNVLFEGKSPHDE
VKKLMRRPQKHEMEQVFHFEE

Sequences:

>Translated_341_residues
MANVAVIGAGSWGTAISLVLADNGHDVLLYGREQEHVDEINSSHTNSFYLKDAPLPESIRATTNLKEALDGRSIVFLVVP
SSAIRPVSKELNTLLTEPVTIVHAAKGIEPKTHERLSEIIAEEIEPAKRRAIGVLTGPTHAEEVAVRKPTTITIACADLD
VADEVQELLTNDQFRVYLNSDVVGAEYGGALKNIIALAAGMTDGLGYGDNAKAALMTRGIVEIARLGVKLGANPASFSGL
TGIGDLIVTATSQHSRNWRAGNAIGRGEKLEDVLGNMGMVVEGVRACEAAHSLAKEAGVEMPITEALYNVLFEGKSPHDE
VKKLMRRPQKHEMEQVFHFEE
>Mature_340_residues
ANVAVIGAGSWGTAISLVLADNGHDVLLYGREQEHVDEINSSHTNSFYLKDAPLPESIRATTNLKEALDGRSIVFLVVPS
SAIRPVSKELNTLLTEPVTIVHAAKGIEPKTHERLSEIIAEEIEPAKRRAIGVLTGPTHAEEVAVRKPTTITIACADLDV
ADEVQELLTNDQFRVYLNSDVVGAEYGGALKNIIALAAGMTDGLGYGDNAKAALMTRGIVEIARLGVKLGANPASFSGLT
GIGDLIVTATSQHSRNWRAGNAIGRGEKLEDVLGNMGMVVEGVRACEAAHSLAKEAGVEMPITEALYNVLFEGKSPHDEV
KKLMRRPQKHEMEQVFHFEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=348, Percent_Identity=29.3103448275862, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=29.2263610315186, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=40.9638554216867, Blast_Score=269, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=28.7323943661972, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564399, Length=347, Percent_Identity=28.5302593659942, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=28.7323943661972, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17507425, Length=286, Percent_Identity=30.4195804195804, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=347, Percent_Identity=25.6484149855908, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=28.3625730994152, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320181, Length=362, Percent_Identity=28.1767955801105, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17136204, Length=348, Percent_Identity=28.448275862069, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17136202, Length=348, Percent_Identity=28.448275862069, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136200, Length=348, Percent_Identity=28.448275862069, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI22026922, Length=368, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45551945, Length=287, Percent_Identity=25.0871080139373, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362270, Length=287, Percent_Identity=25.0871080139373, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_EXISA (C4L6M4)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887348.1
- ProteinModelPortal:   C4L6M4
- GeneID:   7871132
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2989
- OMA:   NVAKGIE
- ProtClustDB:   CLSK2489445
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36629; Mature: 36498

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 106-106 BINDING 106-106 BINDING 141-141 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVAVIGAGSWGTAISLVLADNGHDVLLYGREQEHVDEINSSHTNSFYLKDAPLPESIR
CCCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEEECCCCCHHHH
ATTNLKEALDGRSIVFLVVPSSAIRPVSKELNTLLTEPVTIVHAAKGIEPKTHERLSEII
HHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCHHHHHHHHHH
AEEIEPAKRRAIGVLTGPTHAEEVAVRKPTTITIACADLDVADEVQELLTNDQFRVYLNS
HHHCCHHHHHEEEEEECCCCHHHHEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECC
DVVGAEYGGALKNIIALAAGMTDGLGYGDNAKAALMTRGIVEIARLGVKLGANPASFSGL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TGIGDLIVTATSQHSRNWRAGNAIGRGEKLEDVLGNMGMVVEGVRACEAAHSLAKEAGVE
CCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
MPITEALYNVLFEGKSPHDEVKKLMRRPQKHEMEQVFHFEE
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ANVAVIGAGSWGTAISLVLADNGHDVLLYGREQEHVDEINSSHTNSFYLKDAPLPESIR
CCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEEECCCCCHHHH
ATTNLKEALDGRSIVFLVVPSSAIRPVSKELNTLLTEPVTIVHAAKGIEPKTHERLSEII
HHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHEEHHHCCCCCHHHHHHHHHH
AEEIEPAKRRAIGVLTGPTHAEEVAVRKPTTITIACADLDVADEVQELLTNDQFRVYLNS
HHHCCHHHHHEEEEEECCCCHHHHEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECC
DVVGAEYGGALKNIIALAAGMTDGLGYGDNAKAALMTRGIVEIARLGVKLGANPASFSGL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TGIGDLIVTATSQHSRNWRAGNAIGRGEKLEDVLGNMGMVVEGVRACEAAHSLAKEAGVE
CCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
MPITEALYNVLFEGKSPHDEVKKLMRRPQKHEMEQVFHFEE
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA