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The map label for this gene is engA [H]

Identifier: 229918701

GI number: 229918701

Start: 2951336

End: 2952646

Strand: Direct

Name: engA [H]

Synonym: EAT1b_2988

Alternate gene names: 229918701

Gene position: 2951336-2952646 (Clockwise)

Preceding gene: 229918700

Following gene: 229918702

Centisome position: 98.38

GC content: 48.67

Gene sequence:

>1311_bases
ATGGGAATTCCAGTAGTGGCCATCGTTGGCCGTCCGAATATCGGAAAATCCACAATTTTTAACCGTATCATCGGTGATCG
TGTCTCGATCGTCGATGATAAACCGGGTGTCACACGTGACCGTATTTACGGCACAGGAGAGTGGCTCAACCGTAAGTTCC
ATTTAATCGATACAGGTGGGATCGAAGTAGGGGACGAGCCGTTGCTCGTTCAAATGCGTCATCAGGCGGAACTCGCAATC
GATGAAGCGGACGTCATCATCTTCATGGTGAATGGACGTGAAGGGATCACGGCGGCTGATGAAGAAGTCGCGAACTTGTT
GTTCCGTTCGAACAAACCGATCGTCCTTGCCGTCAACAAAGTCGATAACTTTGAAATGCGAGATCTCATGTATGAGTTTT
ATTCTCTCGGATTTGGAGATCCGTTCCCGATCTCGGGTACACACGGGTTAGGACTCGGTGACTTACTCGACCAAGTATTT
GAACTCGCTCCAGAAAAAGACGAGTACGAATACAACGAAGACGTGATTCAGTTCTCGTTGATTGGTCGCCCGAACGTCGG
GAAATCAAGCTTGACGAACTCAATCCTTGGTGAAGAGCGCGTCATCGTTTCAAACATTGCGGGTACGACTCGTGATGCGA
TTGATACACCGTTCACACGTGACGGACAAGAGTATGTCATCATCGATACGGCAGGTATGCGTAAACGCGGAAAAGTATAT
GAATCGACAGAGCGCTACAGTGTCATGCGCGCACAAAAGGCGATTGAACGCTCGAACGTGGTTCTCGTCGTCCTCGATGG
GGAAGAAGGAATCATCGAGCAAGACAAGCGTGTCGCTGGTCTCGCGCATGAAGCCGGGAAGGCGATTGTCATCGTCGTCA
ATAAATGGGATGCCGTCGAAAAAGATGATAAGACGATGAAGAAGATGGAAGAGAAGATTCGTCAAGAATTCTTATTCCTC
GACTATGCGCCGGTTGTCTTCTTATCAGCGCTCACGTCAAAACGCTTGCAGACATTGTTGCCTGTCATCAAACAAGTGGC
TGAAACACATCGCCGTCGAATCTCGACGAGCGTGTTGAACGATGTCATCGTCGATGCGGTTGCGATGAACCCGACACCGA
CGGATAAAGGACAACGATTGAAGATTAACTACGCAACTCAAGTGGCCATCGAGCCGCCGACGTTCGTCTTGTTCGTCAAC
GATCCTGAGTTGTTGCATTTTTCGTATAAACGTTATTTAGAGAATCAAATCCGTAAAGCATTTGACTTCACCGGGACACC
GATTCACATCGTGGCTCGTCAGAAAAACTAA

Upstream 100 bases:

>100_bases
TTTGTATGGTCACTTAATTTTGCCTGTGATATGATAGGTAAGTTGCGTTTCGAAATGATGAAATGATGAAATTTTGATAG
AAAGTTAGTGAGGTGTTGTT

Downstream 100 bases:

>100_bases
TAACGGGGGTGCCACTTATGGCAAACGTAGCTGTCATCGGAGCAGGGAGCTGGGGAACGGCCATCTCGCTCGTGTTAGCA
GATAATGGCCATGATGTCCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGIPVVAIVGRPNIGKSTIFNRIIGDRVSIVDDKPGVTRDRIYGTGEWLNRKFHLIDTGGIEVGDEPLLVQMRHQAELAI
DEADVIIFMVNGREGITAADEEVANLLFRSNKPIVLAVNKVDNFEMRDLMYEFYSLGFGDPFPISGTHGLGLGDLLDQVF
ELAPEKDEYEYNEDVIQFSLIGRPNVGKSSLTNSILGEERVIVSNIAGTTRDAIDTPFTRDGQEYVIIDTAGMRKRGKVY
ESTERYSVMRAQKAIERSNVVLVVLDGEEGIIEQDKRVAGLAHEAGKAIVIVVNKWDAVEKDDKTMKKMEEKIRQEFLFL
DYAPVVFLSALTSKRLQTLLPVIKQVAETHRRRISTSVLNDVIVDAVAMNPTPTDKGQRLKINYATQVAIEPPTFVLFVN
DPELLHFSYKRYLENQIRKAFDFTGTPIHIVARQKN

Sequences:

>Translated_436_residues
MGIPVVAIVGRPNIGKSTIFNRIIGDRVSIVDDKPGVTRDRIYGTGEWLNRKFHLIDTGGIEVGDEPLLVQMRHQAELAI
DEADVIIFMVNGREGITAADEEVANLLFRSNKPIVLAVNKVDNFEMRDLMYEFYSLGFGDPFPISGTHGLGLGDLLDQVF
ELAPEKDEYEYNEDVIQFSLIGRPNVGKSSLTNSILGEERVIVSNIAGTTRDAIDTPFTRDGQEYVIIDTAGMRKRGKVY
ESTERYSVMRAQKAIERSNVVLVVLDGEEGIIEQDKRVAGLAHEAGKAIVIVVNKWDAVEKDDKTMKKMEEKIRQEFLFL
DYAPVVFLSALTSKRLQTLLPVIKQVAETHRRRISTSVLNDVIVDAVAMNPTPTDKGQRLKINYATQVAIEPPTFVLFVN
DPELLHFSYKRYLENQIRKAFDFTGTPIHIVARQKN
>Mature_435_residues
GIPVVAIVGRPNIGKSTIFNRIIGDRVSIVDDKPGVTRDRIYGTGEWLNRKFHLIDTGGIEVGDEPLLVQMRHQAELAID
EADVIIFMVNGREGITAADEEVANLLFRSNKPIVLAVNKVDNFEMRDLMYEFYSLGFGDPFPISGTHGLGLGDLLDQVFE
LAPEKDEYEYNEDVIQFSLIGRPNVGKSSLTNSILGEERVIVSNIAGTTRDAIDTPFTRDGQEYVIIDTAGMRKRGKVYE
STERYSVMRAQKAIERSNVVLVVLDGEEGIIEQDKRVAGLAHEAGKAIVIVVNKWDAVEKDDKTMKKMEEKIRQEFLFLD
YAPVVFLSALTSKRLQTLLPVIKQVAETHRRRISTSVLNDVIVDAVAMNPTPTDKGQRLKINYATQVAIEPPTFVLFVND
PELLHFSYKRYLENQIRKAFDFTGTPIHIVARQKN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=456, Percent_Identity=41.8859649122807, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=33.8983050847458, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367268, Length=88, Percent_Identity=45.4545454545455, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=115, Percent_Identity=33.9130434782609, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=204, Percent_Identity=30.3921568627451, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48967; Mature: 48836

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPVVAIVGRPNIGKSTIFNRIIGDRVSIVDDKPGVTRDRIYGTGEWLNRKFHLIDTGG
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHEEECHHHHCCEEEEEECCC
IEVGDEPLLVQMRHQAELAIDEADVIIFMVNGREGITAADEEVANLLFRSNKPIVLAVNK
CEECCCCEEEEEECCHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNFEMRDLMYEFYSLGFGDPFPISGTHGLGLGDLLDQVFELAPEKDEYEYNEDVIQFSL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLTNSILGEERVIVSNIAGTTRDAIDTPFTRDGQEYVIIDTAGMRKRGKVY
ECCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCH
ESTERYSVMRAQKAIERSNVVLVVLDGEEGIIEQDKRVAGLAHEAGKAIVIVVNKWDAVE
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHCCHHHHHHHHCCCCEEEEEEECCCCCC
KDDKTMKKMEEKIRQEFLFLDYAPVVFLSALTSKRLQTLLPVIKQVAETHRRRISTSVLN
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIVDAVAMNPTPTDKGQRLKINYATQVAIEPPTFVLFVNDPELLHFSYKRYLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
FDFTGTPIHIVARQKN
HCCCCCCEEEEEECCC
>Mature Secondary Structure 
GIPVVAIVGRPNIGKSTIFNRIIGDRVSIVDDKPGVTRDRIYGTGEWLNRKFHLIDTGG
CCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHEEECHHHHCCEEEEEECCC
IEVGDEPLLVQMRHQAELAIDEADVIIFMVNGREGITAADEEVANLLFRSNKPIVLAVNK
CEECCCCEEEEEECCHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNFEMRDLMYEFYSLGFGDPFPISGTHGLGLGDLLDQVFELAPEKDEYEYNEDVIQFSL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLTNSILGEERVIVSNIAGTTRDAIDTPFTRDGQEYVIIDTAGMRKRGKVY
ECCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCH
ESTERYSVMRAQKAIERSNVVLVVLDGEEGIIEQDKRVAGLAHEAGKAIVIVVNKWDAVE
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHCCHHHHHHHHCCCCEEEEEEECCCCCC
KDDKTMKKMEEKIRQEFLFLDYAPVVFLSALTSKRLQTLLPVIKQVAETHRRRISTSVLN
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIVDAVAMNPTPTDKGQRLKINYATQVAIEPPTFVLFVNDPELLHFSYKRYLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
FDFTGTPIHIVARQKN
HCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA