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The map label for this gene is ymxG [H]

Identifier: 229918675

GI number: 229918675

Start: 2923111

End: 2924328

Strand: Direct

Name: ymxG [H]

Synonym: EAT1b_2962

Alternate gene names: 229918675

Gene position: 2923111-2924328 (Clockwise)

Preceding gene: 229918674

Following gene: 229918676

Centisome position: 97.44

GC content: 49.01

Gene sequence:

>1218_bases
ATGGAATGGATGACATTAGAGAACGGTGTCCGAATCATCATCGAACCAATCGAAGGTTCGCTTAGCACCTCGACCGGGGT
ATTCATTAAAGCAGGGACACGTACAGAGACGTTTGAGAACATCGGCATCAGTCATTTGATTGAACATATGTTGTTCAAAG
GGACCGCATCGAAAAGCGCGAAAGAGATTGCTTCCTTTTTCGATGAGCTCGGTGGAAGCGTCAACGCCTTCACCTCGAAA
GACCATACATGCTTTTACGTGAAGACGCTCGATGAACACGCGGTCATGGCGCTCGACGTCCTGACAGACATGCTGTTTGA
GTCGGTGCTCGATGCACAGGAGTTAGAAAAAGAAAAGCGTGTCGTTGTGGAAGAGATTAAAATGTATGAGGATACACCGG
AAGATCTCGTTCACGAACTATTGGCCATCGCGGCGTATCGGGACGATATCCTCGCCCAACCGATTTTAGGGACGGAGGAG
AGTGTCAATCGATTGACGCGTGACCAGCTCGTCGAATACTTACAAGAACAGTATACGGCCGAGCAGATTGTCGTCTCGAT
CGCAGGTCATGTTTCTGAAGAATTGATTGAGGCGGTAAAACGTAGGTTTGCCCACATCCCTTCTAGGGAATCGTCGAAAG
AAATCAATCAACCGGAACTGTTCCATGACACATTGACGAAACATAAGGAAACGGAGCAAGCCCACCTCTGTTGGAACTAC
GAAGCGATTCCGGCGACGGACGATCGATTGCCTCATTTGGCATTGATGAACAACGCAATCGGCGCGACGATGTCTTCGCG
TTTGTTCCAGTCCATCCGTGAAGAAGAGGGCTTGGCTTATTCCATTTACTCCTATTACACGACGTTTTCCGATCACGGTA
CGTTTACCATATACGTCGGTACGTCGCCGGATACGTTGGAACAAGTCGAAGTCATCCTAGAGAGAGAGATGAAGCGACTT
GTCGCCGACGGTTTGACTGCTGAGGAAGTAGACAAAGGCAAGCGACAATTGAAAGGGTCGATCGCTCTTGGGAATGAAAG
TTCGAGTGCCCGTATGAATCGGAACGGACGGAACTTGCTACTTCTCGATGAAGTCGAGCCGATAGAACAAGTGATTGCCA
AAGTAGAACGGATTGAACGCGATGAGGTCAATACATTGATTCGTGAGGTGTTGAGCCATCGCCCAGCGAAGTCATATGTC
CTCCCAAACGAAGCGTGA

Upstream 100 bases:

>100_bases
TCCGCCACGTCGTGACGGGGACCGTCGTCCACCGCGCTCGACAAATTAATTATTCTGGCCATCGTCTTGGTGCGATGGCC
TTTTTCATAGGAGTGAGAAT

Downstream 100 bases:

>100_bases
CTTGAAACCGAATTGTAAGTTCTCTACACTGATTAAGAGGTATTCTTTAGTTTGGATAGGATACAGGTGAAAGAAGGGAA
AGACTTGAACTTAACGGATT

Product: peptidase M16 domain protein

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MEWMTLENGVRIIIEPIEGSLSTSTGVFIKAGTRTETFENIGISHLIEHMLFKGTASKSAKEIASFFDELGGSVNAFTSK
DHTCFYVKTLDEHAVMALDVLTDMLFESVLDAQELEKEKRVVVEEIKMYEDTPEDLVHELLAIAAYRDDILAQPILGTEE
SVNRLTRDQLVEYLQEQYTAEQIVVSIAGHVSEELIEAVKRRFAHIPSRESSKEINQPELFHDTLTKHKETEQAHLCWNY
EAIPATDDRLPHLALMNNAIGATMSSRLFQSIREEEGLAYSIYSYYTTFSDHGTFTIYVGTSPDTLEQVEVILEREMKRL
VADGLTAEEVDKGKRQLKGSIALGNESSSARMNRNGRNLLLLDEVEPIEQVIAKVERIERDEVNTLIREVLSHRPAKSYV
LPNEA

Sequences:

>Translated_405_residues
MEWMTLENGVRIIIEPIEGSLSTSTGVFIKAGTRTETFENIGISHLIEHMLFKGTASKSAKEIASFFDELGGSVNAFTSK
DHTCFYVKTLDEHAVMALDVLTDMLFESVLDAQELEKEKRVVVEEIKMYEDTPEDLVHELLAIAAYRDDILAQPILGTEE
SVNRLTRDQLVEYLQEQYTAEQIVVSIAGHVSEELIEAVKRRFAHIPSRESSKEINQPELFHDTLTKHKETEQAHLCWNY
EAIPATDDRLPHLALMNNAIGATMSSRLFQSIREEEGLAYSIYSYYTTFSDHGTFTIYVGTSPDTLEQVEVILEREMKRL
VADGLTAEEVDKGKRQLKGSIALGNESSSARMNRNGRNLLLLDEVEPIEQVIAKVERIERDEVNTLIREVLSHRPAKSYV
LPNEA
>Mature_405_residues
MEWMTLENGVRIIIEPIEGSLSTSTGVFIKAGTRTETFENIGISHLIEHMLFKGTASKSAKEIASFFDELGGSVNAFTSK
DHTCFYVKTLDEHAVMALDVLTDMLFESVLDAQELEKEKRVVVEEIKMYEDTPEDLVHELLAIAAYRDDILAQPILGTEE
SVNRLTRDQLVEYLQEQYTAEQIVVSIAGHVSEELIEAVKRRFAHIPSRESSKEINQPELFHDTLTKHKETEQAHLCWNY
EAIPATDDRLPHLALMNNAIGATMSSRLFQSIREEEGLAYSIYSYYTTFSDHGTFTIYVGTSPDTLEQVEVILEREMKRL
VADGLTAEEVDKGKRQLKGSIALGNESSSARMNRNGRNLLLLDEVEPIEQVIAKVERIERDEVNTLIREVLSHRPAKSYV
LPNEA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=413, Percent_Identity=27.3607748184019, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI46593007, Length=401, Percent_Identity=24.4389027431421, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24308013, Length=423, Percent_Identity=21.9858156028369, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI50592988, Length=411, Percent_Identity=20.6812652068127, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1787770, Length=223, Percent_Identity=23.3183856502242, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=25.0620347394541, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17553678, Length=423, Percent_Identity=23.8770685579196, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323192, Length=421, Percent_Identity=28.7410926365796, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6321813, Length=413, Percent_Identity=22.5181598062954, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357875, Length=413, Percent_Identity=27.3607748184019, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24646943, Length=413, Percent_Identity=27.3607748184019, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19921772, Length=432, Percent_Identity=24.3055555555556, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45794; Mature: 45794

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWMTLENGVRIIIEPIEGSLSTSTGVFIKAGTRTETFENIGISHLIEHMLFKGTASKSA
CCCEEECCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCHHH
KEIASFFDELGGSVNAFTSKDHTCFYVKTLDEHAVMALDVLTDMLFESVLDAQELEKEKR
HHHHHHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VVVEEIKMYEDTPEDLVHELLAIAAYRDDILAQPILGTEESVNRLTRDQLVEYLQEQYTA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQIVVSIAGHVSEELIEAVKRRFAHIPSRESSKEINQPELFHDTLTKHKETEQAHLCWNY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECC
EAIPATDDRLPHLALMNNAIGATMSSRLFQSIREEEGLAYSIYSYYTTFSDHGTFTIYVG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCCEEEEEEC
TSPDTLEQVEVILEREMKRLVADGLTAEEVDKGKRQLKGSIALGNESSSARMNRNGRNLL
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEE
LLDEVEPIEQVIAKVERIERDEVNTLIREVLSHRPAKSYVLPNEA
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEWMTLENGVRIIIEPIEGSLSTSTGVFIKAGTRTETFENIGISHLIEHMLFKGTASKSA
CCCEEECCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCHHH
KEIASFFDELGGSVNAFTSKDHTCFYVKTLDEHAVMALDVLTDMLFESVLDAQELEKEKR
HHHHHHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VVVEEIKMYEDTPEDLVHELLAIAAYRDDILAQPILGTEESVNRLTRDQLVEYLQEQYTA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQIVVSIAGHVSEELIEAVKRRFAHIPSRESSKEINQPELFHDTLTKHKETEQAHLCWNY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECC
EAIPATDDRLPHLALMNNAIGATMSSRLFQSIREEEGLAYSIYSYYTTFSDHGTFTIYVG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCCEEEEEEC
TSPDTLEQVEVILEREMKRLVADGLTAEEVDKGKRQLKGSIALGNESSSARMNRNGRNLL
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEE
LLDEVEPIEQVIAKVERIERDEVNTLIREVLSHRPAKSYVLPNEA
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]