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The map label for this gene is frr [H]

Identifier: 229918658

GI number: 229918658

Start: 2902788

End: 2903348

Strand: Direct

Name: frr [H]

Synonym: EAT1b_2945

Alternate gene names: 229918658

Gene position: 2902788-2903348 (Clockwise)

Preceding gene: 229918657

Following gene: 229918659

Centisome position: 96.76

GC content: 42.96

Gene sequence:

>561_bases
ATGAGTGTCAAAGAAGTATTGAAAACAGCTGAAGAAAAAATGGAAAAAGCGCATTCTTCACTTAAACGTGATTTTGGAAC
GCTTCGCACTGGCCGTGCCAGCGCATCGATTTTGGATCCTGTCCAAGTTGATTACTATGGTGTCCCAACACCACTCAATC
AAGTGGCAAACATCAATACACCAGAAGCGCGTCTACTTTTGATTCAACCATGGGATAAGTCGATGGTTTCTGAAGTAGAG
AAAGCGATTCAAAAGGCAGACCTCGGCTTGTCTCCATCATCTGACGGTACGGTCATCCGTTTGGCGATTCCTGCATTGAC
GGAAGAACGTCGTAAAGAATTAGTTAAAATCACGAAAAAATACGCAGAAGAAGCGAAGGTCGCTGTCCGTAACGTACGTC
GTGATGCAAACGAAAACTTGAAGAAACTCGAGAAAGATGGCGAGTTAACAGAAGACGATCTCCGCGGATATGCAGATGAC
GTTCAAACGTTGACGGATTCGTATATCAAGAAGATTGATGAATCTGCAGCAATTAAAGAAAAAGAAATCATGGAAGTGTA
A

Upstream 100 bases:

>100_bases
ACCACATTCCATTGATTGTATTCTCATTGCTTGAAGAAGGTAACATTAAACGTGTCGTTCTCGGGGAACATATCGGGACG
GTAGTAGGAGGAGTCAATTC

Downstream 100 bases:

>100_bases
TCACGGAAGTGGTATACCAAAAAGCTGTGTGGGGACCCTTTTTCTGAGAGGGTCCTTCTTTCATACAATCAGGAGGATAA
CAGAATGTTTAAATGGGTGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVKEVLKTAEEKMEKAHSSLKRDFGTLRTGRASASILDPVQVDYYGVPTPLNQVANINTPEARLLLIQPWDKSMVSEVE
KAIQKADLGLSPSSDGTVIRLAIPALTEERRKELVKITKKYAEEAKVAVRNVRRDANENLKKLEKDGELTEDDLRGYADD
VQTLTDSYIKKIDESAAIKEKEIMEV

Sequences:

>Translated_186_residues
MSVKEVLKTAEEKMEKAHSSLKRDFGTLRTGRASASILDPVQVDYYGVPTPLNQVANINTPEARLLLIQPWDKSMVSEVE
KAIQKADLGLSPSSDGTVIRLAIPALTEERRKELVKITKKYAEEAKVAVRNVRRDANENLKKLEKDGELTEDDLRGYADD
VQTLTDSYIKKIDESAAIKEKEIMEV
>Mature_185_residues
SVKEVLKTAEEKMEKAHSSLKRDFGTLRTGRASASILDPVQVDYYGVPTPLNQVANINTPEARLLLIQPWDKSMVSEVEK
AIQKADLGLSPSSDGTVIRLAIPALTEERRKELVKITKKYAEEAKVAVRNVRRDANENLKKLEKDGELTEDDLRGYADDV
QTLTDSYIKKIDESAAIKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI291042689, Length=191, Percent_Identity=31.413612565445, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=51.9125683060109, Blast_Score=184, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=28.3236994219653, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20843; Mature: 20712

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKEVLKTAEEKMEKAHSSLKRDFGTLRTGRASASILDPVQVDYYGVPTPLNQVANINT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCC
PEARLLLIQPWDKSMVSEVEKAIQKADLGLSPSSDGTVIRLAIPALTEERRKELVKITKK
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
YAEEAKVAVRNVRRDANENLKKLEKDGELTEDDLRGYADDVQTLTDSYIKKIDESAAIKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIMEV
HHHHCC
>Mature Secondary Structure 
SVKEVLKTAEEKMEKAHSSLKRDFGTLRTGRASASILDPVQVDYYGVPTPLNQVANINT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCC
PEARLLLIQPWDKSMVSEVEKAIQKADLGLSPSSDGTVIRLAIPALTEERRKELVKITKK
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
YAEEAKVAVRNVRRDANENLKKLEKDGELTEDDLRGYADDVQTLTDSYIKKIDESAAIKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEIMEV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA