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The map label for this gene is sucD [H]

Identifier: 229918616

GI number: 229918616

Start: 2866501

End: 2867418

Strand: Direct

Name: sucD [H]

Synonym: EAT1b_2903

Alternate gene names: 229918616

Gene position: 2866501-2867418 (Clockwise)

Preceding gene: 229918615

Following gene: 229918617

Centisome position: 95.55

GC content: 50.98

Gene sequence:

>918_bases
ATGAGTATTTGGGCGGATAAAGATACGAAAGTAATCATTCAAGGGATTACAGGGAAGCAAGGTCTGTTCCACGGTGAACA
GATGCTCGCATATAACACGAAATTAGTCGGTGGTGTCACACCTGGTAAAGGTGGCACGACGGTCCTCGACAACGTTCCAG
TCTTCAACACCGTTTCTGAAGCGGTCGAAGCGACTGGTGCCAATGCATCGATCATCTATGTTCCACCTGCTTTCGCAGCG
GATTCGATCATGGAAGCGGCTGATAGCGGCATCGAGCTCATCATCTGTATCACAGAAGGAATCCCAGTTGTAGACATGAT
TCAAGTGAAACGTTATCTCGAGGACAAACCGGCTCGTTTAATCGGACCAAACTGTCCTGGTATCATCACACCAGGAGAAG
CAAAACTTGGCATCATGCCTGGCTATATTCATACGAAAGGGCACGTCGGAATCGTATCACGTTCTGGGACGCTCACGTAT
GAGGCGGTTCATCAGTTGACGACAGCAGGTATCGGTCAGTCGACGGCTGTCGGAATCGGGGGAGACCCGGTCAACGGAAC
AAACTTCATCGATACGCTCAAAGCGTTCAACGAAGATGAGGACACGAAAGCGGTCATCATGATCGGGGAAATCGGTGGAA
CGGCTGAAGAAGAGGCAGCTGAATGGGTAAAAGCCAACATGACGAAACCGGTCATCGGTTTCATCGGCGGGCAGACGGCT
CCTGAAGGCAAGCGTATGGGACATGCGGGCGCAATCATCTCAGGTGGTAAAGGGACGGCTGCTGAGAAGATCAAGACATT
GAACGCGAATGGGATCGAAGTCGCTGAAACACCGGCGGTCATCGGTGAAACATTGATTCGTGTCTTGAAACAGCAAGGAT
TATACGAAGCGTGTGTCACGGGGCAACCGACGACATAA

Upstream 100 bases:

>100_bases
GCGCATTCTCGATGAATCTGGACTTGCGATCACGACGGCCAACTCGATGGCTGACGGTGCAGAAAAAATCGCAGCACTTG
TTCGATAAGGGGGAAACGAC

Downstream 100 bases:

>100_bases
GAATCTTGAGGGATGCTTGCATCCCTCATTTTTTTAAAGGAGAGTTTGTGATGAATCAAACAATAGCTCGGTTTGCTGCA
GCGCGAATGCCAGTTGAGTT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSIWADKDTKVIIQGITGKQGLFHGEQMLAYNTKLVGGVTPGKGGTTVLDNVPVFNTVSEAVEATGANASIIYVPPAFAA
DSIMEAADSGIELIICITEGIPVVDMIQVKRYLEDKPARLIGPNCPGIITPGEAKLGIMPGYIHTKGHVGIVSRSGTLTY
EAVHQLTTAGIGQSTAVGIGGDPVNGTNFIDTLKAFNEDEDTKAVIMIGEIGGTAEEEAAEWVKANMTKPVIGFIGGQTA
PEGKRMGHAGAIISGGKGTAAEKIKTLNANGIEVAETPAVIGETLIRVLKQQGLYEACVTGQPTT

Sequences:

>Translated_305_residues
MSIWADKDTKVIIQGITGKQGLFHGEQMLAYNTKLVGGVTPGKGGTTVLDNVPVFNTVSEAVEATGANASIIYVPPAFAA
DSIMEAADSGIELIICITEGIPVVDMIQVKRYLEDKPARLIGPNCPGIITPGEAKLGIMPGYIHTKGHVGIVSRSGTLTY
EAVHQLTTAGIGQSTAVGIGGDPVNGTNFIDTLKAFNEDEDTKAVIMIGEIGGTAEEEAAEWVKANMTKPVIGFIGGQTA
PEGKRMGHAGAIISGGKGTAAEKIKTLNANGIEVAETPAVIGETLIRVLKQQGLYEACVTGQPTT
>Mature_304_residues
SIWADKDTKVIIQGITGKQGLFHGEQMLAYNTKLVGGVTPGKGGTTVLDNVPVFNTVSEAVEATGANASIIYVPPAFAAD
SIMEAADSGIELIICITEGIPVVDMIQVKRYLEDKPARLIGPNCPGIITPGEAKLGIMPGYIHTKGHVGIVSRSGTLTYE
AVHQLTTAGIGQSTAVGIGGDPVNGTNFIDTLKAFNEDEDTKAVIMIGEIGGTAEEEAAEWVKANMTKPVIGFIGGQTAP
EGKRMGHAGAIISGGKGTAAEKIKTLNANGIEVAETPAVIGETLIRVLKQQGLYEACVTGQPTT

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=60.2693602693603, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI38569423, Length=262, Percent_Identity=29.0076335877863, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38569421, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=66.2068965517241, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=61.4035087719298, Blast_Score=329, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=59.3856655290102, Blast_Score=327, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI17557344, Length=328, Percent_Identity=27.1341463414634, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551266, Length=328, Percent_Identity=26.5243902439024, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=49.1525423728814, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=55.1724137931034, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI28574296, Length=289, Percent_Identity=56.401384083045, Blast_Score=293, Evalue=9e-80,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31612; Mature: 31480

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWADKDTKVIIQGITGKQGLFHGEQMLAYNTKLVGGVTPGKGGTTVLDNVPVFNTVSE
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCEEEECCCCCCCCCEEECCCCCHHHHHH
AVEATGANASIIYVPPAFAADSIMEAADSGIELIICITEGIPVVDMIQVKRYLEDKPARL
HHHHCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
IGPNCPGIITPGEAKLGIMPGYIHTKGHVGIVSRSGTLTYEAVHQLTTAGIGQSTAVGIG
ECCCCCCEECCCCCEEEECCCEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECC
GDPVNGTNFIDTLKAFNEDEDTKAVIMIGEIGGTAEEEAAEWVKANMTKPVIGFIGGQTA
CCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
PEGKRMGHAGAIISGGKGTAAEKIKTLNANGIEVAETPAVIGETLIRVLKQQGLYEACVT
CCCCCCCCCCEEEECCCCCHHHHHEECCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHCC
GQPTT
CCCCC
>Mature Secondary Structure 
SIWADKDTKVIIQGITGKQGLFHGEQMLAYNTKLVGGVTPGKGGTTVLDNVPVFNTVSE
CCCCCCCCEEEEEECCCCCCCCCCCEEEEECCEEEECCCCCCCCCEEECCCCCHHHHHH
AVEATGANASIIYVPPAFAADSIMEAADSGIELIICITEGIPVVDMIQVKRYLEDKPARL
HHHHCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
IGPNCPGIITPGEAKLGIMPGYIHTKGHVGIVSRSGTLTYEAVHQLTTAGIGQSTAVGIG
ECCCCCCEECCCCCEEEECCCEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECC
GDPVNGTNFIDTLKAFNEDEDTKAVIMIGEIGGTAEEEAAEWVKANMTKPVIGFIGGQTA
CCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
PEGKRMGHAGAIISGGKGTAAEKIKTLNANGIEVAETPAVIGETLIRVLKQQGLYEACVT
CCCCCCCCCCEEEECCCCCHHHHHEECCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHCC
GQPTT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]