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The map label for this gene is sucC

Identifier: 229918615

GI number: 229918615

Start: 2865328

End: 2866488

Strand: Direct

Name: sucC

Synonym: EAT1b_2902

Alternate gene names: 229918615

Gene position: 2865328-2866488 (Clockwise)

Preceding gene: 229918614

Following gene: 229918616

Centisome position: 95.51

GC content: 50.13

Gene sequence:

>1161_bases
ATGAATATCCATGAGTATCAGGCGAAAGAATTGTTAAGAGAGTTTGGGGTAGCCGTTCCGACGGGTTATCCGGCCTTTAC
TGTTGAAGAAGCTGTGGCAGCTGCTGCGAAGCTTGACGGTGAAGTGAAGGTAGTAAAAGCTCAAATCCACGCAGGTGGCC
GCGGTAAAGCGGGTGGCGTTAAACTTGCGAAGACAGATGAAGAAGTGAAGCAATATGCTTCAGAGATTCTCGGGAAAACG
CTCGTGACACACCAAACAGGTCCGGAAGGAAAAGTTGTCCAGCGTCTCTATATCGAAGAAGGTTCTGCGATTGACCAAGA
ATTTTACTTAGGGCTCGTGCTTGACCGTTCGATCGGCCGAATTGTCATCATGGGTTCATCTGAAGGTGGAATGGACATCG
AAGAAGTCGCTGAACATACACCAGAGAAGATTCATAAAGAGATCGTCGACCCGGTCGTGGGCTTACGTCCATTCCAGGCG
CGTCGTCTCGCATTCAAAATGGAAGTCCCGACGAAACTCGTCAACGAGTTCAGTGACATGGTCATGAAGTTGTACAAAGT
GTACGTCGAGACAGATTGCACAATCGCGGAAATCAACCCGCTCGTCACGACGAAAGACGGCAACGTCATCGCGCTCGATG
CGAAGTTGAACTTCGATAGCAACGCGCTCTATCGTCACTCGGACATCCTTGCGCTTCGTGATACGACGGAAGAAGACCCA
CGTGAAGTGGAAGCGTCGAAACACGACCTCAGCTACATCGCACTCGACGGAAACATAGGTTGTCTCGTCAACGGTGCCGG
TCTTGCGATGGCTACGATGGATATCATCAAGCATTACGGCGCTGAACCCGCTAACTTCCTCGACGTAGGTGGCGGTGCGA
CGAAAGAAAAAGTAACAGAAGCATTCAAGTTGATCTTGTCTGATGACCAGGTCAAAGGAATCTTCGTTAACATTTTCGGT
GGAATCATGAAGTGTGACATCATCGCAGAGGGGATTGTCGCTGCGACGAAAGAAATCGGACTCGACTTACCACTCGTCGT
TCGCTTAGAAGGAACGAACGTTGATGCCGGGAAGCGCATTCTCGATGAATCTGGACTTGCGATCACGACGGCCAACTCGA
TGGCTGACGGTGCAGAAAAAATCGCAGCACTTGTTCGATAA

Upstream 100 bases:

>100_bases
AAAAAAAGATGAAAACTTAAAGCAAGAACGATAGACAGCGCTTTCAGTTTTTCGTTACAATAGACGTGCCGATATTAAAG
GGGACTAAGGGGGAAAACAT

Downstream 100 bases:

>100_bases
GGGGGAAACGACATGAGTATTTGGGCGGATAAAGATACGAAAGTAATCATTCAAGGGATTACAGGGAAGCAAGGTCTGTT
CCACGGTGAACAGATGCTCG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKELLREFGVAVPTGYPAFTVEEAVAAAAKLDGEVKVVKAQIHAGGRGKAGGVKLAKTDEEVKQYASEILGKT
LVTHQTGPEGKVVQRLYIEEGSAIDQEFYLGLVLDRSIGRIVIMGSSEGGMDIEEVAEHTPEKIHKEIVDPVVGLRPFQA
RRLAFKMEVPTKLVNEFSDMVMKLYKVYVETDCTIAEINPLVTTKDGNVIALDAKLNFDSNALYRHSDILALRDTTEEDP
REVEASKHDLSYIALDGNIGCLVNGAGLAMATMDIIKHYGAEPANFLDVGGGATKEKVTEAFKLILSDDQVKGIFVNIFG
GIMKCDIIAEGIVAATKEIGLDLPLVVRLEGTNVDAGKRILDESGLAITTANSMADGAEKIAALVR

Sequences:

>Translated_386_residues
MNIHEYQAKELLREFGVAVPTGYPAFTVEEAVAAAAKLDGEVKVVKAQIHAGGRGKAGGVKLAKTDEEVKQYASEILGKT
LVTHQTGPEGKVVQRLYIEEGSAIDQEFYLGLVLDRSIGRIVIMGSSEGGMDIEEVAEHTPEKIHKEIVDPVVGLRPFQA
RRLAFKMEVPTKLVNEFSDMVMKLYKVYVETDCTIAEINPLVTTKDGNVIALDAKLNFDSNALYRHSDILALRDTTEEDP
REVEASKHDLSYIALDGNIGCLVNGAGLAMATMDIIKHYGAEPANFLDVGGGATKEKVTEAFKLILSDDQVKGIFVNIFG
GIMKCDIIAEGIVAATKEIGLDLPLVVRLEGTNVDAGKRILDESGLAITTANSMADGAEKIAALVR
>Mature_386_residues
MNIHEYQAKELLREFGVAVPTGYPAFTVEEAVAAAAKLDGEVKVVKAQIHAGGRGKAGGVKLAKTDEEVKQYASEILGKT
LVTHQTGPEGKVVQRLYIEEGSAIDQEFYLGLVLDRSIGRIVIMGSSEGGMDIEEVAEHTPEKIHKEIVDPVVGLRPFQA
RRLAFKMEVPTKLVNEFSDMVMKLYKVYVETDCTIAEINPLVTTKDGNVIALDAKLNFDSNALYRHSDILALRDTTEEDP
REVEASKHDLSYIALDGNIGCLVNGAGLAMATMDIIKHYGAEPANFLDVGGGATKEKVTEAFKLILSDDQVKGIFVNIFG
GIMKCDIIAEGIVAATKEIGLDLPLVVRLEGTNVDAGKRILDESGLAITTANSMADGAEKIAALVR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=49.1048593350384, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=47.5195822454308, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=47.6323119777159, Blast_Score=325, Evalue=5e-89,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=53.7662337662338, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17539378, Length=389, Percent_Identity=46.5295629820051, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=43.0769230769231, Blast_Score=316, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.4444444444444, Blast_Score=344, Evalue=1e-95,
Organism=Drosophila melanogaster, GI161078106, Length=396, Percent_Identity=44.6969696969697, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24645208, Length=396, Percent_Identity=44.6969696969697, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.3551637279597, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI281361397, Length=397, Percent_Identity=44.8362720403023, Blast_Score=327, Evalue=9e-90,
Organism=Drosophila melanogaster, GI281361395, Length=397, Percent_Identity=44.8362720403023, Blast_Score=327, Evalue=9e-90,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_EXISA (C4L610)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887261.1
- GeneID:   7870157
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2902
- OMA:   MADGAEK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41656; Mature: 41656

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKELLREFGVAVPTGYPAFTVEEAVAAAAKLDGEVKVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCE
KLAKTDEEVKQYASEILGKTLVTHQTGPEGKVVQRLYIEEGSAIDQEFYLGLVLDRSIGR
EEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCCHHHEEEEEEECCCCE
IVIMGSSEGGMDIEEVAEHTPEKIHKEIVDPVVGLRPFQARRLAFKMEVPTKLVNEFSDM
EEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHH
VMKLYKVYVETDCTIAEINPLVTTKDGNVIALDAKLNFDSNALYRHSDILALRDTTEEDP
HHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEEEECCCCCCEEECCCEEEECCCCCCCC
REVEASKHDLSYIALDGNIGCLVNGAGLAMATMDIIKHYGAEPANFLDVGGGATKEKVTE
HHHHCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLILSDDQVKGIFVNIFGGIMKCDIIAEGIVAATKEIGLDLPLVVRLEGTNVDAGKRI
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
LDESGLAITTANSMADGAEKIAALVR
HCCCCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKELLREFGVAVPTGYPAFTVEEAVAAAAKLDGEVKVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCE
KLAKTDEEVKQYASEILGKTLVTHQTGPEGKVVQRLYIEEGSAIDQEFYLGLVLDRSIGR
EEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCCHHHEEEEEEECCCCE
IVIMGSSEGGMDIEEVAEHTPEKIHKEIVDPVVGLRPFQARRLAFKMEVPTKLVNEFSDM
EEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHH
VMKLYKVYVETDCTIAEINPLVTTKDGNVIALDAKLNFDSNALYRHSDILALRDTTEEDP
HHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEEEECCCCCCEEECCCEEEECCCCCCCC
REVEASKHDLSYIALDGNIGCLVNGAGLAMATMDIIKHYGAEPANFLDVGGGATKEKVTE
HHHHCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLILSDDQVKGIFVNIFGGIMKCDIIAEGIVAATKEIGLDLPLVVRLEGTNVDAGKRI
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
LDESGLAITTANSMADGAEKIAALVR
HCCCCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA