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The map label for this gene is recG [H]

Identifier: 229918594

GI number: 229918594

Start: 2846515

End: 2848545

Strand: Direct

Name: recG [H]

Synonym: EAT1b_2881

Alternate gene names: 229918594

Gene position: 2846515-2848545 (Clockwise)

Preceding gene: 229918593

Following gene: 229918595

Centisome position: 94.89

GC content: 51.35

Gene sequence:

>2031_bases
ATGCAAAACAATGATCGACTGACGACGCTGAAAGGGGTCGGGCCAGAGATGGCCAAAAAGTTAGAAGTGATGGGACTTGT
TCGAATCGAGGACGTGCTGGAGCACGTCCCGTTTCGTTATGAGAATTATAATAGTGGGACGGTGACGACGGCTGTTCATG
GTGACCTCGTCAAGTGGAGCGGGACTGTCCAAGCCGAACCGCTCGTTCGCTACTATAGTAAAGGGAAGAATCGTCTTCAG
TTCCGGTTGTTACTCGAAGACCGATACGCCGTCCAAGTAACGATGTTCAACCGTGCCTTCTATAAAGAAAAATTGGTGAT
CGGGGAGACGGTGACGGTCAAAGGGAAATGGGACATGAACCGGATGACGATCAGCGCGACCGACCTTGAATTTGGTGCCC
CCTCAGGCGGATTGCAACCGATTTATTCATTACGAGCCGGGCTGACACAAAAGAATTTCAGTCGGATCGTGAAGCTCGCT
TTTGAGCAGGTGAACGATTTGCCCGAACAGGTCCCGCAAGCCATTCGCGACCGCTATCGATTAGTTGACCGGATGACGAT
GCTACGTGGGATGCATTTTCCAGATACAGTGGAGACCTATAAACAGGCGAGACGAAGCTACGTTTATGAAGAGTGTCTCA
TGTATCAGTTGAAATTACAGGCGTTTCGGAAAATGGAGCGGTCAGGAAACGGTCGGGCCCTTCATCTCGATAAGCATCAA
TTGAATGAATTCGTCAAACGGCTCGCATTCCCATTAACCGGAGCCCAGACACGGGTCATCCGTGAAATCGTATCTGACCT
TGAAAGACCAGAACGGATGAACCGATTGTTACAAGGGGATGTCGGGAGCGGGAAGACCGTCGTTGCCGCGATTGCCTTGT
ATGCGACTGTGACGGCCGGGTATCAAGGGGCTTTGATGGTGCCAACAGAAATCCTTGCCGAACAACATGCGACATCGTTA
CAGGAATTATTTGAACCGTTTGGTATCACGATCGCCCTCCTGACGAGCTCGGTGAAAGGGAAGGCGCGCGAAGCCCTCCT
GACGGCAATTCGATCGGGTGACGTCGACATCATCGTCGGGACGCACGCGCTCATCCAAGGACCAGTCGAATTTTCAAATT
TACATTTGGCAATCACAGATGAACAACATCGATTCGGTGTCGAACAACGGAAGAAACTTCGCGATAAAGCTGAATTCGCG
GACGTCTTATACATGACCGCGACGCCGATTCCAAGGACGCTTGCAATCAGTGCGTTCGGAGAGATGGATGTTTCCACGAT
CGATGAGATGCCAAAAGGACGAAAGCCGATTGAAACGTATTGGGCGAAACACGACCAGATCGATCGTGTGCATACAATGG
TCGATCGGGAACTCGCACTCGGCCGTCAAGCGTATGTGATTGCACCTCTCATCGAGGAGTCGGATACACTAGAAGTGGAG
AGTGCGACGGCACTGTATGAGCTGTTGAAAGAACGCTTCTCGAACTATGGTGTTGGTCTGATGCACGGGAAGCTATCGAG
TACAGAAAAAGACGAGGTCATGAAATCATTCGCCGACAACGCGACACAGATTCTCGTCTCCACAACGGTCGTCGAGGTCG
GGGTGAACGTTCCAAACGCTTCACTCATCATCATCCATGACGCCGAGCGTTTCGGTCTCGCGCAATTACACCAGTTGCGT
GGCCGTGTCGGTCGTGGTGCCCATCAATCGTTCTGTATCCTCGTCGGGGACCCAAAGTCAGATGTCGGAAAAGTTCGACT
GAAAACGATGACGGAGACGAACGATGGGTTCGTATTGGCGGAGAAAGATTTAGAGTTACGTGGGGCTGGTGATTTCTTCG
GGACCGCACAAAGTGGTCTCCCAAGTTTCCGGGTCGCCGATCCCGTTCTCGATTTGAAAGTGATGGAAGTGGCCATGCAA
GATGCTGTGAAACTTCTCGGAAGCGACGCCTTTTGGCATGACGCCCAATATGAAGGGTTACGTGGCTATTTGAAACAACT
CGACCTTCTCGTTGGGGAAAGGTTAGAATAG

Upstream 100 bases:

>100_bases
CAAATGATGCCGACCGCCTTAAAAGAGACGGCAAAAGGCGGACTTGCCAATACACCGACGGCTCGTCGCCTCGAACGAAA
TATATTTGGAGCGAAAGAAG

Downstream 100 bases:

>100_bases
TACTTGAAAATGACGACTAAAGAATATATACTGCTATTAGTACCAGGTATTAAGTTCTTTAGCGATTAGTTTAGGAGGGA
ACTGAATGCGGGTACCTAAG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MQNNDRLTTLKGVGPEMAKKLEVMGLVRIEDVLEHVPFRYENYNSGTVTTAVHGDLVKWSGTVQAEPLVRYYSKGKNRLQ
FRLLLEDRYAVQVTMFNRAFYKEKLVIGETVTVKGKWDMNRMTISATDLEFGAPSGGLQPIYSLRAGLTQKNFSRIVKLA
FEQVNDLPEQVPQAIRDRYRLVDRMTMLRGMHFPDTVETYKQARRSYVYEECLMYQLKLQAFRKMERSGNGRALHLDKHQ
LNEFVKRLAFPLTGAQTRVIREIVSDLERPERMNRLLQGDVGSGKTVVAAIALYATVTAGYQGALMVPTEILAEQHATSL
QELFEPFGITIALLTSSVKGKAREALLTAIRSGDVDIIVGTHALIQGPVEFSNLHLAITDEQHRFGVEQRKKLRDKAEFA
DVLYMTATPIPRTLAISAFGEMDVSTIDEMPKGRKPIETYWAKHDQIDRVHTMVDRELALGRQAYVIAPLIEESDTLEVE
SATALYELLKERFSNYGVGLMHGKLSSTEKDEVMKSFADNATQILVSTTVVEVGVNVPNASLIIIHDAERFGLAQLHQLR
GRVGRGAHQSFCILVGDPKSDVGKVRLKTMTETNDGFVLAEKDLELRGAGDFFGTAQSGLPSFRVADPVLDLKVMEVAMQ
DAVKLLGSDAFWHDAQYEGLRGYLKQLDLLVGERLE

Sequences:

>Translated_676_residues
MQNNDRLTTLKGVGPEMAKKLEVMGLVRIEDVLEHVPFRYENYNSGTVTTAVHGDLVKWSGTVQAEPLVRYYSKGKNRLQ
FRLLLEDRYAVQVTMFNRAFYKEKLVIGETVTVKGKWDMNRMTISATDLEFGAPSGGLQPIYSLRAGLTQKNFSRIVKLA
FEQVNDLPEQVPQAIRDRYRLVDRMTMLRGMHFPDTVETYKQARRSYVYEECLMYQLKLQAFRKMERSGNGRALHLDKHQ
LNEFVKRLAFPLTGAQTRVIREIVSDLERPERMNRLLQGDVGSGKTVVAAIALYATVTAGYQGALMVPTEILAEQHATSL
QELFEPFGITIALLTSSVKGKAREALLTAIRSGDVDIIVGTHALIQGPVEFSNLHLAITDEQHRFGVEQRKKLRDKAEFA
DVLYMTATPIPRTLAISAFGEMDVSTIDEMPKGRKPIETYWAKHDQIDRVHTMVDRELALGRQAYVIAPLIEESDTLEVE
SATALYELLKERFSNYGVGLMHGKLSSTEKDEVMKSFADNATQILVSTTVVEVGVNVPNASLIIIHDAERFGLAQLHQLR
GRVGRGAHQSFCILVGDPKSDVGKVRLKTMTETNDGFVLAEKDLELRGAGDFFGTAQSGLPSFRVADPVLDLKVMEVAMQ
DAVKLLGSDAFWHDAQYEGLRGYLKQLDLLVGERLE
>Mature_676_residues
MQNNDRLTTLKGVGPEMAKKLEVMGLVRIEDVLEHVPFRYENYNSGTVTTAVHGDLVKWSGTVQAEPLVRYYSKGKNRLQ
FRLLLEDRYAVQVTMFNRAFYKEKLVIGETVTVKGKWDMNRMTISATDLEFGAPSGGLQPIYSLRAGLTQKNFSRIVKLA
FEQVNDLPEQVPQAIRDRYRLVDRMTMLRGMHFPDTVETYKQARRSYVYEECLMYQLKLQAFRKMERSGNGRALHLDKHQ
LNEFVKRLAFPLTGAQTRVIREIVSDLERPERMNRLLQGDVGSGKTVVAAIALYATVTAGYQGALMVPTEILAEQHATSL
QELFEPFGITIALLTSSVKGKAREALLTAIRSGDVDIIVGTHALIQGPVEFSNLHLAITDEQHRFGVEQRKKLRDKAEFA
DVLYMTATPIPRTLAISAFGEMDVSTIDEMPKGRKPIETYWAKHDQIDRVHTMVDRELALGRQAYVIAPLIEESDTLEVE
SATALYELLKERFSNYGVGLMHGKLSSTEKDEVMKSFADNATQILVSTTVVEVGVNVPNASLIIIHDAERFGLAQLHQLR
GRVGRGAHQSFCILVGDPKSDVGKVRLKTMTETNDGFVLAEKDLELRGAGDFFGTAQSGLPSFRVADPVLDLKVMEVAMQ
DAVKLLGSDAFWHDAQYEGLRGYLKQLDLLVGERLE

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=663, Percent_Identity=39.9698340874811, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787357, Length=396, Percent_Identity=37.1212121212121, Blast_Score=249, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75847; Mature: 75847

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00435 PEROXIDASE_1 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNDRLTTLKGVGPEMAKKLEVMGLVRIEDVLEHVPFRYENYNSGTVTTAVHGDLVKWS
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEEC
GTVQAEPLVRYYSKGKNRLQFRLLLEDRYAVQVTMFNRAFYKEKLVIGETVTVKGKWDMN
CCCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEEEEHHHHHHHHEEECCEEEEEECCCCC
RMTISATDLEFGAPSGGLQPIYSLRAGLTQKNFSRIVKLAFEQVNDLPEQVPQAIRDRYR
EEEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVDRMTMLRGMHFPDTVETYKQARRSYVYEECLMYQLKLQAFRKMERSGNGRALHLDKHQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHH
LNEFVKRLAFPLTGAQTRVIREIVSDLERPERMNRLLQGDVGSGKTVVAAIALYATVTAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
YQGALMVPTEILAEQHATSLQELFEPFGITIALLTSSVKGKAREALLTAIRSGDVDIIVG
CCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEC
THALIQGPVEFSNLHLAITDEQHRFGVEQRKKLRDKAEFADVLYMTATPIPRTLAISAFG
CHHHHCCCCEECCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCC
EMDVSTIDEMPKGRKPIETYWAKHDQIDRVHTMVDRELALGRQAYVIAPLIEESDTLEVE
CCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEHH
SATALYELLKERFSNYGVGLMHGKLSSTEKDEVMKSFADNATQILVSTTVVEVGVNVPNA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCHHEEHHEEEEEEECCCCCCC
SLIIIHDAERFGLAQLHQLRGRVGRGAHQSFCILVGDPKSDVGKVRLKTMTETNDGFVLA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCEEEE
EKDLELRGAGDFFGTAQSGLPSFRVADPVLDLKVMEVAMQDAVKLLGSDAFWHDAQYEGL
ECCCEEECCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RGYLKQLDLLVGERLE
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQNNDRLTTLKGVGPEMAKKLEVMGLVRIEDVLEHVPFRYENYNSGTVTTAVHGDLVKWS
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEEC
GTVQAEPLVRYYSKGKNRLQFRLLLEDRYAVQVTMFNRAFYKEKLVIGETVTVKGKWDMN
CCCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEEEEHHHHHHHHEEECCEEEEEECCCCC
RMTISATDLEFGAPSGGLQPIYSLRAGLTQKNFSRIVKLAFEQVNDLPEQVPQAIRDRYR
EEEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVDRMTMLRGMHFPDTVETYKQARRSYVYEECLMYQLKLQAFRKMERSGNGRALHLDKHQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHH
LNEFVKRLAFPLTGAQTRVIREIVSDLERPERMNRLLQGDVGSGKTVVAAIALYATVTAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
YQGALMVPTEILAEQHATSLQELFEPFGITIALLTSSVKGKAREALLTAIRSGDVDIIVG
CCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEC
THALIQGPVEFSNLHLAITDEQHRFGVEQRKKLRDKAEFADVLYMTATPIPRTLAISAFG
CHHHHCCCCEECCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCC
EMDVSTIDEMPKGRKPIETYWAKHDQIDRVHTMVDRELALGRQAYVIAPLIEESDTLEVE
CCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEHH
SATALYELLKERFSNYGVGLMHGKLSSTEKDEVMKSFADNATQILVSTTVVEVGVNVPNA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCHHEEHHEEEEEEECCCCCCC
SLIIIHDAERFGLAQLHQLRGRVGRGAHQSFCILVGDPKSDVGKVRLKTMTETNDGFVLA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCEEEE
EKDLELRGAGDFFGTAQSGLPSFRVADPVLDLKVMEVAMQDAVKLLGSDAFWHDAQYEGL
ECCCEEECCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RGYLKQLDLLVGERLE
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]