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The map label for this gene is sdaAA [H]

Identifier: 229918593

GI number: 229918593

Start: 2845641

End: 2846528

Strand: Direct

Name: sdaAA [H]

Synonym: EAT1b_2880

Alternate gene names: 229918593

Gene position: 2845641-2846528 (Clockwise)

Preceding gene: 229918592

Following gene: 229918594

Centisome position: 94.86

GC content: 55.74

Gene sequence:

>888_bases
ATGTTTAAATCAGTAGAGGAATTAGTGACGATTGCAACAGAACGGAACATCCCGATTTCTGAAGTGATGATCGAGCAGGA
GATGCATGTCAGACGTGCCAGTCGAGAGGACATCATCGGGATGATGGACCGAAATCTTGAAGTGATGGAGGAGGCGGTCG
AACGCGCACTCCAAGGTGTCACGTCGGTTACGGGATTGACGGGGAATGATGCCGTACTCATGCAAGACTACATTCGTTCG
GGCAAGTCGCTCGCGGGAGACCTCATTTTAGATGCCGTCTCGAAAGCGATTGGGACGAACGAAGTGAACGCGGCGATGGG
ACGAATCTGTGCGACACCGACGGCGGGGAGCGCGGGCGTCGTACCGGGAACGTTGTTTGCGGTAAAAGATCGTCTTGAAA
TGGACCGCGACGCGATGATCCGTTACTTGTTCACATCAGGTGCGTTCGGATTCGTCGTGGCGAACAACGCCTCGATTTCA
GGGGCGGCTGGTGGATGTCAGGCCGAGGTCGGGTCGGCGACGGGCATGGCAGCCGCGGCCATCGTTGAAGCAGCTGGCGG
GACACCGGACCAATCGGCCACGGCATTTGCGATCGCCCTAAAAAATATGCTCGGTCTCGTCTGTGATCCTGTGGCGGGGT
TGGTCGAAGTTCCATGCGTCAAGCGAAATGCCATGGGCGGTGCCAACGCCATTGTCGCAGCAGATATGGCGCTTGCGGGG
ATTACCTCACGTATCCCTTGTGACGAGGTCATCTCGGCGATGCATGAAGTGGGCCAAATGATGCCGACCGCCTTAAAAGA
GACGGCAAAAGGCGGACTTGCCAATACACCGACGGCTCGTCGCCTCGAACGAAATATATTTGGAGCGAAAGAAGATGCAA
AACAATGA

Upstream 100 bases:

>100_bases
TGAGATTGATGAGACCATTCCTGCGGAAGTGATCGCAGAGCTGGAACGGTTACCGCAAATCGAACGGATAGCTATTTTTG
GGGAATGAGGAGAATGTGTG

Downstream 100 bases:

>100_bases
TCGACTGACGACGCTGAAAGGGGTCGGGCCAGAGATGGCCAAAAAGTTAGAAGTGATGGGACTTGTTCGAATCGAGGACG
TGCTGGAGCACGTCCCGTTT

Product: L-serine dehydratase, iron-sulfur-dependent, subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MFKSVEELVTIATERNIPISEVMIEQEMHVRRASREDIIGMMDRNLEVMEEAVERALQGVTSVTGLTGNDAVLMQDYIRS
GKSLAGDLILDAVSKAIGTNEVNAAMGRICATPTAGSAGVVPGTLFAVKDRLEMDRDAMIRYLFTSGAFGFVVANNASIS
GAAGGCQAEVGSATGMAAAAIVEAAGGTPDQSATAFAIALKNMLGLVCDPVAGLVEVPCVKRNAMGGANAIVAADMALAG
ITSRIPCDEVISAMHEVGQMMPTALKETAKGGLANTPTARRLERNIFGAKEDAKQ

Sequences:

>Translated_295_residues
MFKSVEELVTIATERNIPISEVMIEQEMHVRRASREDIIGMMDRNLEVMEEAVERALQGVTSVTGLTGNDAVLMQDYIRS
GKSLAGDLILDAVSKAIGTNEVNAAMGRICATPTAGSAGVVPGTLFAVKDRLEMDRDAMIRYLFTSGAFGFVVANNASIS
GAAGGCQAEVGSATGMAAAAIVEAAGGTPDQSATAFAIALKNMLGLVCDPVAGLVEVPCVKRNAMGGANAIVAADMALAG
ITSRIPCDEVISAMHEVGQMMPTALKETAKGGLANTPTARRLERNIFGAKEDAKQ
>Mature_295_residues
MFKSVEELVTIATERNIPISEVMIEQEMHVRRASREDIIGMMDRNLEVMEEAVERALQGVTSVTGLTGNDAVLMQDYIRS
GKSLAGDLILDAVSKAIGTNEVNAAMGRICATPTAGSAGVVPGTLFAVKDRLEMDRDAMIRYLFTSGAFGFVVANNASIS
GAAGGCQAEVGSATGMAAAAIVEAAGGTPDQSATAFAIALKNMLGLVCDPVAGLVEVPCVKRNAMGGANAIVAADMALAG
ITSRIPCDEVISAMHEVGQMMPTALKETAKGGLANTPTARRLERNIFGAKEDAKQ

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=280, Percent_Identity=36.4285714285714, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1788116, Length=280, Percent_Identity=37.1428571428571, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789161, Length=284, Percent_Identity=36.2676056338028, Blast_Score=154, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30638; Mature: 30638

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSVEELVTIATERNIPISEVMIEQEMHVRRASREDIIGMMDRNLEVMEEAVERALQGV
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TSVTGLTGNDAVLMQDYIRSGKSLAGDLILDAVSKAIGTNEVNAAMGRICATPTAGSAGV
HHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
VPGTLFAVKDRLEMDRDAMIRYLFTSGAFGFVVANNASISGAAGGCQAEVGSATGMAAAA
CCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
IVEAAGGTPDQSATAFAIALKNMLGLVCDPVAGLVEVPCVKRNAMGGANAIVAADMALAG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHH
ITSRIPCDEVISAMHEVGQMMPTALKETAKGGLANTPTARRLERNIFGAKEDAKQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MFKSVEELVTIATERNIPISEVMIEQEMHVRRASREDIIGMMDRNLEVMEEAVERALQGV
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TSVTGLTGNDAVLMQDYIRSGKSLAGDLILDAVSKAIGTNEVNAAMGRICATPTAGSAGV
HHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
VPGTLFAVKDRLEMDRDAMIRYLFTSGAFGFVVANNASISGAAGGCQAEVGSATGMAAAA
CCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
IVEAAGGTPDQSATAFAIALKNMLGLVCDPVAGLVEVPCVKRNAMGGANAIVAADMALAG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHH
ITSRIPCDEVISAMHEVGQMMPTALKETAKGGLANTPTARRLERNIFGAKEDAKQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]