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The map label for this gene is fabG [H]

Identifier: 229918460

GI number: 229918460

Start: 2718246

End: 2718971

Strand: Reverse

Name: fabG [H]

Synonym: EAT1b_2747

Alternate gene names: 229918460

Gene position: 2718971-2718246 (Counterclockwise)

Preceding gene: 229918464

Following gene: 229918455

Centisome position: 90.64

GC content: 52.2

Gene sequence:

>726_bases
ATGGGGACTTTTCTAATCACCGGTGCGACAAGTGGGATTGGTCGCGCCGTCGCTTTGCAGTTGACTGGTAAGGGGCACCG
TGTCATCGGGATTGGTCGGGACGAAACGAGAGGTGCCGCCCTCGAGTCTGATTCAAATGGACAAGCCACATTTATTCGAT
GTGACCTTGCTTCTACAGAGGACATCGATCATCTTTTCGCTCAGTTAAAAGAGCAAGGTGTGACCTTGAACGGATTATTC
AATAACGCTGCCACATTCGGCAGACCGGGCACCCCTGAGCGTTTGACACATGAGTCGTATACTGAGGTGTTCGAGGTCAA
CCTGTATGCACTGAACACCGTCACACAGCGCGCCATTCCCTTGTTTGACCAAGGAGCGAGTGTTGTCAACAATGCCGCCA
TCGTCGGGCACGTCAAGTTCCCTCCGATGCTCGCGCACTATGCCGCTTCAAAAGCGGCCGTAGTGGCCTTAACCAAAACG
TTCGCGCACCGAATGAAAGGAAAAGTAAGATTCAATGCCGTTTGTTTCGGACCGATTGATACACCTCTCAGTCACAAGCT
ATACGGCGGGGAAGCGAAGTTTAAAGAGGCGATGACCCATCATTTCCGGGGACATGCCGCCCTCCCTGAGGAAGTAGCAC
CGGTCGTCGAATTTTTGTTGACGGATGCCTCAACGTATATTAACGGTCAAGCCATCACGGTCGATGGCGGGTATACATTG
TCTTGA

Upstream 100 bases:

>100_bases
TGTATGCGTCGCAACATATTATAAGCTGACCTCGTTTCTGTCATGTATTATCATTAATTATACATCGTAACATCATCTTT
TTGAGGGGAGCGAATAAATT

Downstream 100 bases:

>100_bases
ACAGCGACCACCTCTTCTTTTGAACAGGTGGTTGCTACTCATGTCGCCATCTTTTTAGCCCGATTGATCTTATTATGCAA
ATAGTTCTGTTCTTTCACAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGTFLITGATSGIGRAVALQLTGKGHRVIGIGRDETRGAALESDSNGQATFIRCDLASTEDIDHLFAQLKEQGVTLNGLF
NNAATFGRPGTPERLTHESYTEVFEVNLYALNTVTQRAIPLFDQGASVVNNAAIVGHVKFPPMLAHYAASKAAVVALTKT
FAHRMKGKVRFNAVCFGPIDTPLSHKLYGGEAKFKEAMTHHFRGHAALPEEVAPVVEFLLTDASTYINGQAITVDGGYTL
S

Sequences:

>Translated_241_residues
MGTFLITGATSGIGRAVALQLTGKGHRVIGIGRDETRGAALESDSNGQATFIRCDLASTEDIDHLFAQLKEQGVTLNGLF
NNAATFGRPGTPERLTHESYTEVFEVNLYALNTVTQRAIPLFDQGASVVNNAAIVGHVKFPPMLAHYAASKAAVVALTKT
FAHRMKGKVRFNAVCFGPIDTPLSHKLYGGEAKFKEAMTHHFRGHAALPEEVAPVVEFLLTDASTYINGQAITVDGGYTL
S
>Mature_240_residues
GTFLITGATSGIGRAVALQLTGKGHRVIGIGRDETRGAALESDSNGQATFIRCDLASTEDIDHLFAQLKEQGVTLNGLFN
NAATFGRPGTPERLTHESYTEVFEVNLYALNTVTQRAIPLFDQGASVVNNAAIVGHVKFPPMLAHYAASKAAVVALTKTF
AHRMKGKVRFNAVCFGPIDTPLSHKLYGGEAKFKEAMTHHFRGHAALPEEVAPVVEFLLTDASTYINGQAITVDGGYTLS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=222, Percent_Identity=31.0810810810811, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI109715829, Length=230, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=31.9230769230769, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.968253968254, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=30.4526748971193, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=27.9166666666667, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=30.8943089430894, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=28.9795918367347, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=29.1497975708502, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=31.2, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=30.1526717557252, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=30.3501945525292, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=243, Percent_Identity=30.4526748971193, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=31.3953488372093, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.6772908366534, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=27.4590163934426, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=30.1470588235294, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=256, Percent_Identity=29.6875, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=28.6307053941909, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.3076923076923, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=276, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.4436090225564, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.7449392712551, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=30.8943089430894, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=28.2442748091603, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=30.2904564315353, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=30.2904564315353, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=30, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=32.7868852459016, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.8548387096774, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=29.7520661157025, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=30.8943089430894, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25789; Mature: 25657

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTFLITGATSGIGRAVALQLTGKGHRVIGIGRDETRGAALESDSNGQATFIRCDLASTE
CCEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCCCCEECCCCCCCEEEEEEECCCCC
DIDHLFAQLKEQGVTLNGLFNNAATFGRPGTPERLTHESYTEVFEVNLYALNTVTQRAIP
CHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCHHHHHHEEEEEEEEECHHHHHHCC
LFDQGASVVNNAAIVGHVKFPPMLAHYAASKAAVVALTKTFAHRMKGKVRFNAVCFGPID
CCCCCHHHHCCCEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHCCCEEEEEEEECCCC
TPLSHKLYGGEAKFKEAMTHHFRGHAALPEEVAPVVEFLLTDASTYINGQAITVDGGYTL
CCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHEECCEEEEECCCEEC
S
C
>Mature Secondary Structure 
GTFLITGATSGIGRAVALQLTGKGHRVIGIGRDETRGAALESDSNGQATFIRCDLASTE
CEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCCCCEECCCCCCCEEEEEEECCCCC
DIDHLFAQLKEQGVTLNGLFNNAATFGRPGTPERLTHESYTEVFEVNLYALNTVTQRAIP
CHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCHHHHHHEEEEEEEEECHHHHHHCC
LFDQGASVVNNAAIVGHVKFPPMLAHYAASKAAVVALTKTFAHRMKGKVRFNAVCFGPID
CCCCCHHHHCCCEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHCCCEEEEEEEECCCC
TPLSHKLYGGEAKFKEAMTHHFRGHAALPEEVAPVVEFLLTDASTYINGQAITVDGGYTL
CCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHEECCEEEEECCCEEC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]