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The map label for this gene is fabF [H]

Identifier: 229918445

GI number: 229918445

Start: 2701878

End: 2703110

Strand: Direct

Name: fabF [H]

Synonym: EAT1b_2732

Alternate gene names: 229918445

Gene position: 2701878-2703110 (Clockwise)

Preceding gene: 229918444

Following gene: 229918446

Centisome position: 90.07

GC content: 51.82

Gene sequence:

>1233_bases
ATGAAACGAGTAGTAGTGACAGGATTAGGAGTCGTATCACCATTAGGAAACGATGTCTCAACAATGTGGGATCGCCTGTT
AAAAGGGGATAACGCGATTGATACGTTGACGAAGATTGACATCAGTCAATATCCGGCTAAGGTCGGGGCGGAAGTGAAGG
AATGGAATATCGATCATTTAGTCGAACCGAAGGAAGCACGTAAGATGGACTCCTTCATCCAATATTCTTTACTTGCGGCA
GACGCTGCCCACAAGGATAGCGGACTCGACGTGAAAGCCATCGCGGACGATGTCGGGATTTGGATTGGGAGCGGGATTGG
TGGCGTCGAGACGATTGACAAACAGTCGGCCATCTTGCATGACCGTGGACCACGTCGCGTCAGCCCGTTCTTCATTCCGA
TGATGATTCCGAACATGGCGAGCGGACAAGTATCCATCTATCTTGGAGCAAAGGGACCGAGCAACTGTTCCGTGACGGCT
TGTGCGTCAGGAACGAACTCCATCGGGGAAGCGTTCCGTGTCATTCAACGTGGCGATGCGATCGCCATGTTCGCAGGTGG
AGCGGAAGCGCCAATCACACCACTCTCGTTCGCAGGATTCTGTTCGAACAAAGCACTTTCAACGAATCCGGACCCGAACA
CGGCGTGCCGTCCGTTCGATGAAAACCGTGACGGATTCGTCATGGGTGAAGGAGCCGGGGTGCTCGTCTTGGAGGAGTAT
GAACATGCGAAAGCACGTGGTGCGAAAATGTATGCTGAAGTTGTCGGATATGGGATGAGTTCGGATGCTTACCATATCAC
AGCACCATCCCCTGAAGCAGAGGGCGGATCGAAAGCGATGAGTGAGGCGATTCGAGACGCCGGAATCACGCCAGAAGATG
TTCAATACATCAACGCGCACGGAACGAGTACACCACTCAACGATATGCTCGAGACGAAAGCGATTCGTCGTGTGTTCGGG
GAACACGCTGATAAGCTCGCCGTCAACTCCTCAAAATCGATGATCGGTCACCTTCTCGGTGGTGCAGGTGGCGTCGAGGC
CGTCATCACAGCACTTTCGATTCATGAAGGCAAGATTCATCCAACGATTAACTGCGAATCACCAGCTGCAGATTGTGATT
TAGATTATGTACGTGAAGGAAATCGGGAACTTGACATTCGTTATGCACTCAGTAACTCACTCGGCTTCGGGGGCCACAAT
GCGACACTCGCATTTGCAAAAGTGACGAACTGA

Upstream 100 bases:

>100_bases
ATGGACAAACGGTCGTCATCGCAGGGTTTGGTGCCGGACTCACCTGGGGGGCTAGCTGTCTGACATGGAATCACGCAACC
ATTACGGAGGGGAATCATTT

Downstream 100 bases:

>100_bases
CGGTAGAAAAATCATTCAAAAAAGGTTAGGGTATAAGGGTTGGTCTAACAGAAAGGAGTGCAACGAATGAAAAAGAAATC
ATTCATCGTGGCCGCCTTGT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKRVVVTGLGVVSPLGNDVSTMWDRLLKGDNAIDTLTKIDISQYPAKVGAEVKEWNIDHLVEPKEARKMDSFIQYSLLAA
DAAHKDSGLDVKAIADDVGIWIGSGIGGVETIDKQSAILHDRGPRRVSPFFIPMMIPNMASGQVSIYLGAKGPSNCSVTA
CASGTNSIGEAFRVIQRGDAIAMFAGGAEAPITPLSFAGFCSNKALSTNPDPNTACRPFDENRDGFVMGEGAGVLVLEEY
EHAKARGAKMYAEVVGYGMSSDAYHITAPSPEAEGGSKAMSEAIRDAGITPEDVQYINAHGTSTPLNDMLETKAIRRVFG
EHADKLAVNSSKSMIGHLLGGAGGVEAVITALSIHEGKIHPTINCESPAADCDLDYVREGNRELDIRYALSNSLGFGGHN
ATLAFAKVTN

Sequences:

>Translated_410_residues
MKRVVVTGLGVVSPLGNDVSTMWDRLLKGDNAIDTLTKIDISQYPAKVGAEVKEWNIDHLVEPKEARKMDSFIQYSLLAA
DAAHKDSGLDVKAIADDVGIWIGSGIGGVETIDKQSAILHDRGPRRVSPFFIPMMIPNMASGQVSIYLGAKGPSNCSVTA
CASGTNSIGEAFRVIQRGDAIAMFAGGAEAPITPLSFAGFCSNKALSTNPDPNTACRPFDENRDGFVMGEGAGVLVLEEY
EHAKARGAKMYAEVVGYGMSSDAYHITAPSPEAEGGSKAMSEAIRDAGITPEDVQYINAHGTSTPLNDMLETKAIRRVFG
EHADKLAVNSSKSMIGHLLGGAGGVEAVITALSIHEGKIHPTINCESPAADCDLDYVREGNRELDIRYALSNSLGFGGHN
ATLAFAKVTN
>Mature_410_residues
MKRVVVTGLGVVSPLGNDVSTMWDRLLKGDNAIDTLTKIDISQYPAKVGAEVKEWNIDHLVEPKEARKMDSFIQYSLLAA
DAAHKDSGLDVKAIADDVGIWIGSGIGGVETIDKQSAILHDRGPRRVSPFFIPMMIPNMASGQVSIYLGAKGPSNCSVTA
CASGTNSIGEAFRVIQRGDAIAMFAGGAEAPITPLSFAGFCSNKALSTNPDPNTACRPFDENRDGFVMGEGAGVLVLEEY
EHAKARGAKMYAEVVGYGMSSDAYHITAPSPEAEGGSKAMSEAIRDAGITPEDVQYINAHGTSTPLNDMLETKAIRRVFG
EHADKLAVNSSKSMIGHLLGGAGGVEAVITALSIHEGKIHPTINCESPAADCDLDYVREGNRELDIRYALSNSLGFGGHN
ATLAFAKVTN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=47.3557692307692, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=50.6756756756757, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI41872631, Length=416, Percent_Identity=25.4807692307692, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=49.7560975609756, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788663, Length=417, Percent_Identity=37.1702637889688, Blast_Score=209, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71983541, Length=420, Percent_Identity=36.9047619047619, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=42.7480916030534, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI212642053, Length=427, Percent_Identity=27.1662763466042, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=372, Percent_Identity=25.5376344086022, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=37.6975169300226, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24644341, Length=416, Percent_Identity=45.1923076923077, Blast_Score=340, Evalue=9e-94,
Organism=Drosophila melanogaster, GI221330659, Length=398, Percent_Identity=25.6281407035176, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920632, Length=398, Percent_Identity=25.6281407035176, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=22.4824355971897, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43385; Mature: 43385

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVVVTGLGVVSPLGNDVSTMWDRLLKGDNAIDTLTKIDISQYPAKVGAEVKEWNIDHL
CCEEEEECCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCHHHCCHHHCCCHHCCCHHHC
VEPKEARKMDSFIQYSLLAADAAHKDSGLDVKAIADDVGIWIGSGIGGVETIDKQSAILH
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCCCHHHCHHHHHHH
DRGPRRVSPFFIPMMIPNMASGQVSIYLGAKGPSNCSVTACASGTNSIGEAFRVIQRGDA
CCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCE
IAMFAGGAEAPITPLSFAGFCSNKALSTNPDPNTACRPFDENRDGFVMGEGAGVLVLEEY
EEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECC
EHAKARGAKMYAEVVGYGMSSDAYHITAPSPEAEGGSKAMSEAIRDAGITPEDVQYINAH
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHEEEECC
GTSTPLNDMLETKAIRRVFGEHADKLAVNSSKSMIGHLLGGAGGVEAVITALSIHEGKIH
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PTINCESPAADCDLDYVREGNRELDIRYALSNSLGFGGHNATLAFAKVTN
CEECCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKRVVVTGLGVVSPLGNDVSTMWDRLLKGDNAIDTLTKIDISQYPAKVGAEVKEWNIDHL
CCEEEEECCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCHHHCCHHHCCCHHCCCHHHC
VEPKEARKMDSFIQYSLLAADAAHKDSGLDVKAIADDVGIWIGSGIGGVETIDKQSAILH
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCCCHHHCHHHHHHH
DRGPRRVSPFFIPMMIPNMASGQVSIYLGAKGPSNCSVTACASGTNSIGEAFRVIQRGDA
CCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCE
IAMFAGGAEAPITPLSFAGFCSNKALSTNPDPNTACRPFDENRDGFVMGEGAGVLVLEEY
EEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECC
EHAKARGAKMYAEVVGYGMSSDAYHITAPSPEAEGGSKAMSEAIRDAGITPEDVQYINAH
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHEEEECC
GTSTPLNDMLETKAIRRVFGEHADKLAVNSSKSMIGHLLGGAGGVEAVITALSIHEGKIH
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PTINCESPAADCDLDYVREGNRELDIRYALSNSLGFGGHNATLAFAKVTN
CEECCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]