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The map label for this gene is fabH1 [H]

Identifier: 229918444

GI number: 229918444

Start: 2700922

End: 2701881

Strand: Direct

Name: fabH1 [H]

Synonym: EAT1b_2731

Alternate gene names: 229918444

Gene position: 2700922-2701881 (Clockwise)

Preceding gene: 229918443

Following gene: 229918445

Centisome position: 90.03

GC content: 52.19

Gene sequence:

>960_bases
ATGAATATTGGAATCATCGGCATCGGATCGTTCTTACCGGACAATCGGGTGACAAATATCGATTTAGAAAAACGAATGGA
TACGAGCGATGAGTGGATTCGTACTCGTACAGGCATCGAGGCACGTCATTTGGCTGAAGGTGATGTGACGGTCGCGGATA
TGGCGACACGTGCCGCTGAACGGGCGTTACAGAGCGCGGGCGTCTCAATCGATGAGATTGAAGCAATCGTCTGTGCGACA
GCAACGGCGCCAGCCTTCCCGGCAACTGCATGTGTGGTGCAGGCCAATCTTGGCGCGAAAGCCGCTGTCGCCTTCGATGT
GAGCGCGGCATGTAGCGGTTTCATCTTCGCGATGGACACTGCGAAGAGTCTCATGGATTCAAAAGGATTGAAAAAGACGC
TCGTCATTGGCGCAGAGAAGATGGGAAGTCTGATTGATTGGGATGACCGATCGACGGCTGTCCTCTTTGGGGACGGAGCA
GGGGCTGTCGTGCTCGGGGAAGACGAGATTGCTTCAATTGACTCACTTGTGCTCGGAAGTGACGGGACAGGTGGTAAACA
TCTGTATGAAAATGAAGAAGGTAAAATCGTCATGAACGGTCGCGAAGTCTTCAAGTTTGCCGTTCGGAAGATGCCCGAAA
TCGTGCTTGAAGCGCTAGACAAAGCAGACAAGACGTTGGAAGATCTTGACGTCCTCGTTCCACACCAGGCGAACCGTCGA
ATCATCGACGCTGCGATGGAACGGTTACACTTAGAAGAAGAGAAAGTGGTCATGACCATTCAAGACCATGCGAATACATC
AGCAGCTTCCATTCCACTCGCTTTGGCCGAAGCGGTCAAGTCTGGCAAAATCCAAGATGGACAAACGGTCGTCATCGCAG
GGTTTGGTGCCGGACTCACCTGGGGGGCTAGCTGTCTGACATGGAATCACGCAACCATTACGGAGGGGAATCATTTATGA

Upstream 100 bases:

>100_bases
TTAGAACAAGCTTAATCCAGTCTACACGAGGAGGATGCATTGACATCCTCTTTTTATTCCCTTATATTAGTACCAGATAC
TAAGAATAGGGGTCGACGAT

Downstream 100 bases:

>100_bases
AACGAGTAGTAGTGACAGGATTAGGAGTCGTATCACCATTAGGAAACGATGTCTCAACAATGTGGGATCGCCTGTTAAAA
GGGGATAACGCGATTGATAC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNIGIIGIGSFLPDNRVTNIDLEKRMDTSDEWIRTRTGIEARHLAEGDVTVADMATRAAERALQSAGVSIDEIEAIVCAT
ATAPAFPATACVVQANLGAKAAVAFDVSAACSGFIFAMDTAKSLMDSKGLKKTLVIGAEKMGSLIDWDDRSTAVLFGDGA
GAVVLGEDEIASIDSLVLGSDGTGGKHLYENEEGKIVMNGREVFKFAVRKMPEIVLEALDKADKTLEDLDVLVPHQANRR
IIDAAMERLHLEEEKVVMTIQDHANTSAASIPLALAEAVKSGKIQDGQTVVIAGFGAGLTWGASCLTWNHATITEGNHL

Sequences:

>Translated_319_residues
MNIGIIGIGSFLPDNRVTNIDLEKRMDTSDEWIRTRTGIEARHLAEGDVTVADMATRAAERALQSAGVSIDEIEAIVCAT
ATAPAFPATACVVQANLGAKAAVAFDVSAACSGFIFAMDTAKSLMDSKGLKKTLVIGAEKMGSLIDWDDRSTAVLFGDGA
GAVVLGEDEIASIDSLVLGSDGTGGKHLYENEEGKIVMNGREVFKFAVRKMPEIVLEALDKADKTLEDLDVLVPHQANRR
IIDAAMERLHLEEEKVVMTIQDHANTSAASIPLALAEAVKSGKIQDGQTVVIAGFGAGLTWGASCLTWNHATITEGNHL
>Mature_319_residues
MNIGIIGIGSFLPDNRVTNIDLEKRMDTSDEWIRTRTGIEARHLAEGDVTVADMATRAAERALQSAGVSIDEIEAIVCAT
ATAPAFPATACVVQANLGAKAAVAFDVSAACSGFIFAMDTAKSLMDSKGLKKTLVIGAEKMGSLIDWDDRSTAVLFGDGA
GAVVLGEDEIASIDSLVLGSDGTGGKHLYENEEGKIVMNGREVFKFAVRKMPEIVLEALDKADKTLEDLDVLVPHQANRR
IIDAAMERLHLEEEKVVMTIQDHANTSAASIPLALAEAVKSGKIQDGQTVVIAGFGAGLTWGASCLTWNHATITEGNHL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=46.3722397476341, Blast_Score=260, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 33777; Mature: 33777

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIIGIGSFLPDNRVTNIDLEKRMDTSDEWIRTRTGIEARHLAEGDVTVADMATRAAE
CCEEEEEECCCCCCCCEEECCHHHCCCCCHHHHHHHCCCCHHCCCCCCEEHHHHHHHHHH
RALQSAGVSIDEIEAIVCATATAPAFPATACVVQANLGAKAAVAFDVSAACSGFIFAMDT
HHHHHHCCCHHHHHEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCEEEEHHH
AKSLMDSKGLKKTLVIGAEKMGSLIDWDDRSTAVLFGDGAGAVVLGEDEIASIDSLVLGS
HHHHHHHCCCCEEEEEEHHHHCCEECCCCCCEEEEEECCCCEEEECCCHHHCCCCEEECC
DGTGGKHLYENEEGKIVMNGREVFKFAVRKMPEIVLEALDKADKTLEDLDVLVPHQANRR
CCCCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
IIDAAMERLHLEEEKVVMTIQDHANTSAASIPLALAEAVKSGKIQDGQTVVIAGFGAGLT
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
WGASCLTWNHATITEGNHL
CCCCEEEECCEEECCCCCC
>Mature Secondary Structure
MNIGIIGIGSFLPDNRVTNIDLEKRMDTSDEWIRTRTGIEARHLAEGDVTVADMATRAAE
CCEEEEEECCCCCCCCEEECCHHHCCCCCHHHHHHHCCCCHHCCCCCCEEHHHHHHHHHH
RALQSAGVSIDEIEAIVCATATAPAFPATACVVQANLGAKAAVAFDVSAACSGFIFAMDT
HHHHHHCCCHHHHHEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCEEEEHHH
AKSLMDSKGLKKTLVIGAEKMGSLIDWDDRSTAVLFGDGAGAVVLGEDEIASIDSLVLGS
HHHHHHHCCCCEEEEEEHHHHCCEECCCCCCEEEEEECCCCEEEECCCHHHCCCCEEECC
DGTGGKHLYENEEGKIVMNGREVFKFAVRKMPEIVLEALDKADKTLEDLDVLVPHQANRR
CCCCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
IIDAAMERLHLEEEKVVMTIQDHANTSAASIPLALAEAVKSGKIQDGQTVVIAGFGAGLT
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
WGASCLTWNHATITEGNHL
CCCCEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]