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The map label for this gene is dtd

Identifier: 229918417

GI number: 229918417

Start: 2673756

End: 2674199

Strand: Direct

Name: dtd

Synonym: EAT1b_2703

Alternate gene names: 229918417

Gene position: 2673756-2674199 (Clockwise)

Preceding gene: 229918416

Following gene: 229918418

Centisome position: 89.13

GC content: 52.25

Gene sequence:

>444_bases
GTGCGTGTATTATTGCAACGAGTGAAAGAAGCATCGGTCACAGTCGAGGAAGAAGTCGTCGGGGCAATCAACGCCGGATA
CTTGCTTCTCGTCGGTGTGACACATGAAGATACAGAAGAGGAAGTGAACTGGCTCGCCGACAAGGTGACCGGGCTTCGCG
TCTTCGAGGATGATCAAGAAAAGATGAACTTGTCGATTCAAGATGTGTCTGGTCAAATCTTGTCGGTCTCTCAGTTCACT
TTATATGGGGACACGATGAAAGGACGGCGACCTGCTTTCACAAAGGCCGCCAAACCGGACATGGCTGAGACGCTCTATGA
AAAATTCAACGAGCGACTCCGGGCGAACGGGCTCATCGTCGAGACGGGACGCTTCGGTGCGATGATGGACGTCGCACTCG
TTAATGACGGACCGGTCACGCTCATGCTCGAAAAAAACGCTTGA

Upstream 100 bases:

>100_bases
AACGTGAATCACTTGCAGAAAGTCGTCGAGCGCATCAAACAAATCTCAGACGTGTATTCGGTCAGCCGAGTCATGATGAC
GTGACGAAAGGAAGAGGAAC

Downstream 100 bases:

>100_bases
CAGATGCCGGCTTGATTCGGCATCATGAAGCATATAGTCAAACACCTACGATAAAGAAGAGTACGGTCAACCCACCAGCA
AAGAGAGCGATGCCTAGGCT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MRVLLQRVKEASVTVEEEVVGAINAGYLLLVGVTHEDTEEEVNWLADKVTGLRVFEDDQEKMNLSIQDVSGQILSVSQFT
LYGDTMKGRRPAFTKAAKPDMAETLYEKFNERLRANGLIVETGRFGAMMDVALVNDGPVTLMLEKNA

Sequences:

>Translated_147_residues
MRVLLQRVKEASVTVEEEVVGAINAGYLLLVGVTHEDTEEEVNWLADKVTGLRVFEDDQEKMNLSIQDVSGQILSVSQFT
LYGDTMKGRRPAFTKAAKPDMAETLYEKFNERLRANGLIVETGRFGAMMDVALVNDGPVTLMLEKNA
>Mature_147_residues
MRVLLQRVKEASVTVEEEVVGAINAGYLLLVGVTHEDTEEEVNWLADKVTGLRVFEDDQEKMNLSIQDVSGQILSVSQFT
LYGDTMKGRRPAFTKAAKPDMAETLYEKFNERLRANGLIVETGRFGAMMDVALVNDGPVTLMLEKNA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=42.6666666666667, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=53.4722222222222, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115533292, Length=147, Percent_Identity=43.5374149659864, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319982, Length=149, Percent_Identity=43.6241610738255, Blast_Score=128, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=42.4657534246575, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_EXISA (C4L533)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887063.1
- GeneID:   7868907
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2703
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16339; Mature: 16339

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLQRVKEASVTVEEEVVGAINAGYLLLVGVTHEDTEEEVNWLADKVTGLRVFEDDQE
CHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCHH
KMNLSIQDVSGQILSVSQFTLYGDTMKGRRPAFTKAAKPDMAETLYEKFNERLRANGLIV
HHEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEE
ETGRFGAMMDVALVNDGPVTLMLEKNA
ECCCCCCEEEEEEECCCCEEEEEECCC
>Mature Secondary Structure
MRVLLQRVKEASVTVEEEVVGAINAGYLLLVGVTHEDTEEEVNWLADKVTGLRVFEDDQE
CHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCHH
KMNLSIQDVSGQILSVSQFTLYGDTMKGRRPAFTKAAKPDMAETLYEKFNERLRANGLIV
HHEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEE
ETGRFGAMMDVALVNDGPVTLMLEKNA
ECCCCCCEEEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA