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The map label for this gene is pilC [H]

Identifier: 229918377

GI number: 229918377

Start: 2633214

End: 2634431

Strand: Direct

Name: pilC [H]

Synonym: EAT1b_2662

Alternate gene names: 229918377

Gene position: 2633214-2634431 (Clockwise)

Preceding gene: 229918376

Following gene: 229918378

Centisome position: 87.78

GC content: 51.4

Gene sequence:

>1218_bases
ATGGCGATATTTCAGTATGAAGGAAAACTCCTGAACGGGAAGCGTAAGAAAGGTCGCATCACGGCCGTTTCGCTTCGGGA
AGCGAAAGAAAAGTTGCGTCAAGAGTCGATTCTCGTAACGGACTTGTCCGAGCTCGAGTCGACCGGACTGAACATGGAAG
TGAACCTGCTTCCGGAACGGGTAAAAATCGAGCACTTGATCATGTACGTCCGTCAGTTTGCGACGCTCATCCGGGCGGGT
GTCCCGATTGTTCGTGCGACTTCAATCTTACGGGTTCAGACCGAATCGAACGTATTGAAGAAAGCATTGAGTCAAGTCGA
GGACGACTTGAAGGAAGGGATTGCCTATTCTGAGGCGATTAAAAAACACCCACGTGTCTTTTCGAACTTCTTTAGTTCGA
TGGCACTTGCCGGGGAGACGAGTGGGAACTTGGAGGAGGCGCTCGATCAAATCGGGCTCCAACTCCAAAAACAATATGAC
GTGAAGCGGAAGGTCATTTCTGCCCTCACGTATCCGTTGGTCGTTTCCATCGTCGCCATCGGCGTTGTCGCCTTTTTGAT
GGTGAACGTCGTTCCGACATTCGCGAGCATATTCGGTCAACTCGGCGGTGAGCTTCCGCTCATCACACGAATTGTTGTCG
CTGTCTCGGATTTCATCGCGGCCTTCTGGTGGCTGTTACTTGGACTCGCGATTCTCGGAGTTCTCACCTTCACCTGGATG
TTGAAACGGGACCGGGAACGGTTCGTCATCGATGGCTTGCTATTAAAGATGCCGATTTTCGGAACGATTGTGATGAAGTC
TCAGATTGCCTTGTTGACGCGAAGTTTAGCGGTCCTCCTACAGGCAGCCGTCCCGATTTTGACGGCGATTGAAATCACCG
AGCGAATCGTATCGAACCGTGTCATCCGGAAAGGGTTGACCGAAGCGCGTGAGATGATGGCGCAAGGTGTACCACTTCAC
GAACCGCTCATGCGAAATGCGAACTTCCCGGCGCTCATGACACAGATGATTGCCGTCGGGGAAGAGAGTGGAGATTTGGA
TTCGATGTTGAACGAAGTTGCTGAGTTTTATGAGACGGAGGTCGAGACGACAACGGACCGCTTGAAATCGATTATCGAGC
CGCTTCTCATCGTCGTATTGGCAAGCGTCGTCGGGGTCATCGTCATCTCAATCGTCGTCCCGATGTTCCAAATCTATGGT
GATATTCAGAATCAGTAA

Upstream 100 bases:

>100_bases
ACACGGGATGCAGTCGATGGATGCCGCCATCGAACAACTCGTTCGACAAGGGATTATCAACCCGAACGCCGTCCCGACAG
AAGAGATGAGGTGATGAGTG

Downstream 100 bases:

>100_bases
AGCAATATGCAAGCTTTTGAAAATATACCTTTTCAATACTATATTTAGAAGGTATAGTAAAATTGTTCTACTTCTATATT
AGGTCTTAAGTAATTTATTT

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAIFQYEGKLLNGKRKKGRITAVSLREAKEKLRQESILVTDLSELESTGLNMEVNLLPERVKIEHLIMYVRQFATLIRAG
VPIVRATSILRVQTESNVLKKALSQVEDDLKEGIAYSEAIKKHPRVFSNFFSSMALAGETSGNLEEALDQIGLQLQKQYD
VKRKVISALTYPLVVSIVAIGVVAFLMVNVVPTFASIFGQLGGELPLITRIVVAVSDFIAAFWWLLLGLAILGVLTFTWM
LKRDRERFVIDGLLLKMPIFGTIVMKSQIALLTRSLAVLLQAAVPILTAIEITERIVSNRVIRKGLTEAREMMAQGVPLH
EPLMRNANFPALMTQMIAVGEESGDLDSMLNEVAEFYETEVETTTDRLKSIIEPLLIVVLASVVGVIVISIVVPMFQIYG
DIQNQ

Sequences:

>Translated_405_residues
MAIFQYEGKLLNGKRKKGRITAVSLREAKEKLRQESILVTDLSELESTGLNMEVNLLPERVKIEHLIMYVRQFATLIRAG
VPIVRATSILRVQTESNVLKKALSQVEDDLKEGIAYSEAIKKHPRVFSNFFSSMALAGETSGNLEEALDQIGLQLQKQYD
VKRKVISALTYPLVVSIVAIGVVAFLMVNVVPTFASIFGQLGGELPLITRIVVAVSDFIAAFWWLLLGLAILGVLTFTWM
LKRDRERFVIDGLLLKMPIFGTIVMKSQIALLTRSLAVLLQAAVPILTAIEITERIVSNRVIRKGLTEAREMMAQGVPLH
EPLMRNANFPALMTQMIAVGEESGDLDSMLNEVAEFYETEVETTTDRLKSIIEPLLIVVLASVVGVIVISIVVPMFQIYG
DIQNQ
>Mature_404_residues
AIFQYEGKLLNGKRKKGRITAVSLREAKEKLRQESILVTDLSELESTGLNMEVNLLPERVKIEHLIMYVRQFATLIRAGV
PIVRATSILRVQTESNVLKKALSQVEDDLKEGIAYSEAIKKHPRVFSNFFSSMALAGETSGNLEEALDQIGLQLQKQYDV
KRKVISALTYPLVVSIVAIGVVAFLMVNVVPTFASIFGQLGGELPLITRIVVAVSDFIAAFWWLLLGLAILGVLTFTWML
KRDRERFVIDGLLLKMPIFGTIVMKSQIALLTRSLAVLLQAAVPILTAIEITERIVSNRVIRKGLTEAREMMAQGVPLHE
PLMRNANFPALMTQMIAVGEESGDLDSMLNEVAEFYETEVETTTDRLKSIIEPLLIVVLASVVGVIVISIVVPMFQIYGD
IQNQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=397, Percent_Identity=30.2267002518892, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1786295, Length=332, Percent_Identity=28.0120481927711, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44995; Mature: 44864

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFQYEGKLLNGKRKKGRITAVSLREAKEKLRQESILVTDLSELESTGLNMEVNLLPER
CCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
VKIEHLIMYVRQFATLIRAGVPIVRATSILRVQTESNVLKKALSQVEDDLKEGIAYSEAI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KKHPRVFSNFFSSMALAGETSGNLEEALDQIGLQLQKQYDVKRKVISALTYPLVVSIVAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVAFLMVNVVPTFASIFGQLGGELPLITRIVVAVSDFIAAFWWLLLGLAILGVLTFTWM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRDRERFVIDGLLLKMPIFGTIVMKSQIALLTRSLAVLLQAAVPILTAIEITERIVSNR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRKGLTEAREMMAQGVPLHEPLMRNANFPALMTQMIAVGEESGDLDSMLNEVAEFYETE
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VETTTDRLKSIIEPLLIVVLASVVGVIVISIVVPMFQIYGDIQNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIFQYEGKLLNGKRKKGRITAVSLREAKEKLRQESILVTDLSELESTGLNMEVNLLPER
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
VKIEHLIMYVRQFATLIRAGVPIVRATSILRVQTESNVLKKALSQVEDDLKEGIAYSEAI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KKHPRVFSNFFSSMALAGETSGNLEEALDQIGLQLQKQYDVKRKVISALTYPLVVSIVAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVAFLMVNVVPTFASIFGQLGGELPLITRIVVAVSDFIAAFWWLLLGLAILGVLTFTWM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRDRERFVIDGLLLKMPIFGTIVMKSQIALLTRSLAVLLQAAVPILTAIEITERIVSNR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRKGLTEAREMMAQGVPLHEPLMRNANFPALMTQMIAVGEESGDLDSMLNEVAEFYETE
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VETTTDRLKSIIEPLLIVVLASVVGVIVISIVVPMFQIYGDIQNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]