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The map label for this gene is malR [H]

Identifier: 229918226

GI number: 229918226

Start: 2471123

End: 2472181

Strand: Direct

Name: malR [H]

Synonym: EAT1b_2506

Alternate gene names: 229918226

Gene position: 2471123-2472181 (Clockwise)

Preceding gene: 229918225

Following gene: 229918227

Centisome position: 82.37

GC content: 52.12

Gene sequence:

>1059_bases
ATGCAAATCACAATCAAAGATGTGGCGAAGCACGCGAATGTCGCGCCGTCGACAGTCTCTCGCGTCATCGCCAACAGCCC
AAGAATCAGTCAAAAGACAAAAGAACGGGTCAGAAGTTCCATGGAAGAGCTCGGGTATCATCCGAACATTCATGCGAGAA
GTCTCGCTAACCGCTCGACACAGTCGATTGGTCTCGTCATGCCGAGCGCGGCAACAAAGACACTTCAAAACCCGTTCTTC
CCGGAAGTGCTACGAGGAATTAGCACGAAGGCGCACCAGAATGGATACTCGCTTTATATGACGACCGGCGTGACAGAAGA
AGAAGTTTTGTCCGGTGTGATCGAGATGGTACAAGGACGCCGTGTCGACGGTGTCATCGTTCTTTATTCACGTGAAGACG
ACCAAGTCGTCCAATACTTACGTCAAACGAAGTTTCCGTTCGTCGTGGTCGGGAAGCCGTTCGGGGACGCTTCTTCCATC
ACTTACGTCGATACGGACAACTATTTGGCTGGTCGTGAAGTGACGAAACACCTTTATAACTTAGGTCATCGTCGCATCGC
CTTCATCGGGGGCTCGGATAAACTCGCCGTCACACAAGATCGTCGGAACGGGTACGCGACGGCCCTCATGGAAGCAGGCA
TCCCGGTATGCGAAGATTACATCGCCCGGGCTGAATTCATGACGAAGGGTGGCGCGAAGGCCGTGCGTGAACTGTTACAA
AATGAGGAACCACCGACAGCCGTCGTCGTCAGTGACGATATGATGGCACTCGGCGTCATCAGCACGTTAAGCGAGATGGG
GCTCAAGATCCCAGAGGACGTCGCGGTCGTCAGTTTCAATAACGTGTATATCGCGGAACACTCGAACCCGCCACTCACGT
CGGTCGAAATTAACATCTTCGGTCTCGGTTTCGAGGCGACGAACTGTTTGATCGAACAAATCAGTGATAATGCACCCCCT
TATGGGAAGCGTGTCATCGTGCCACATTATCTGGTCGTCCGCCAATCATGTGGGCAGAAGAAAAGTAAGGCGACCGAAAC
ATTAGAATCGAATTCTTAA

Upstream 100 bases:

>100_bases
CCGATTTTCTTGACTGGTTTGGTCATGTGGAAGCGCCGCAAATAAAGACATGAAACGCCGCAAGGCACGAATCGAATTCA
CGGAAGCAGGGGGGAACACC

Downstream 100 bases:

>100_bases
TTTACCAGACGATTTCGCCAGAGCGGAGTCGTCTTTTGCATATCCTTTTGATTGAAGCCTCATGAAGTAGGGAACATCTT
TTTCGAAGGAATCGAAATCG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQITIKDVAKHANVAPSTVSRVIANSPRISQKTKERVRSSMEELGYHPNIHARSLANRSTQSIGLVMPSAATKTLQNPFF
PEVLRGISTKAHQNGYSLYMTTGVTEEEVLSGVIEMVQGRRVDGVIVLYSREDDQVVQYLRQTKFPFVVVGKPFGDASSI
TYVDTDNYLAGREVTKHLYNLGHRRIAFIGGSDKLAVTQDRRNGYATALMEAGIPVCEDYIARAEFMTKGGAKAVRELLQ
NEEPPTAVVVSDDMMALGVISTLSEMGLKIPEDVAVVSFNNVYIAEHSNPPLTSVEINIFGLGFEATNCLIEQISDNAPP
YGKRVIVPHYLVVRQSCGQKKSKATETLESNS

Sequences:

>Translated_352_residues
MQITIKDVAKHANVAPSTVSRVIANSPRISQKTKERVRSSMEELGYHPNIHARSLANRSTQSIGLVMPSAATKTLQNPFF
PEVLRGISTKAHQNGYSLYMTTGVTEEEVLSGVIEMVQGRRVDGVIVLYSREDDQVVQYLRQTKFPFVVVGKPFGDASSI
TYVDTDNYLAGREVTKHLYNLGHRRIAFIGGSDKLAVTQDRRNGYATALMEAGIPVCEDYIARAEFMTKGGAKAVRELLQ
NEEPPTAVVVSDDMMALGVISTLSEMGLKIPEDVAVVSFNNVYIAEHSNPPLTSVEINIFGLGFEATNCLIEQISDNAPP
YGKRVIVPHYLVVRQSCGQKKSKATETLESNS
>Mature_352_residues
MQITIKDVAKHANVAPSTVSRVIANSPRISQKTKERVRSSMEELGYHPNIHARSLANRSTQSIGLVMPSAATKTLQNPFF
PEVLRGISTKAHQNGYSLYMTTGVTEEEVLSGVIEMVQGRRVDGVIVLYSREDDQVVQYLRQTKFPFVVVGKPFGDASSI
TYVDTDNYLAGREVTKHLYNLGHRRIAFIGGSDKLAVTQDRRNGYATALMEAGIPVCEDYIARAEFMTKGGAKAVRELLQ
NEEPPTAVVVSDDMMALGVISTLSEMGLKIPEDVAVVSFNNVYIAEHSNPPLTSVEINIFGLGFEATNCLIEQISDNAPP
YGKRVIVPHYLVVRQSCGQKKSKATETLESNS

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=324, Percent_Identity=32.4074074074074, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787948, Length=318, Percent_Identity=33.0188679245283, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1790194, Length=316, Percent_Identity=31.9620253164557, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=30.625, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1789068, Length=328, Percent_Identity=33.5365853658537, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789202, Length=296, Percent_Identity=31.4189189189189, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788474, Length=351, Percent_Identity=29.6296296296296, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787906, Length=344, Percent_Identity=26.7441860465116, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786540, Length=346, Percent_Identity=29.1907514450867, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994940, Length=292, Percent_Identity=26.7123287671233, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=27.1386430678466, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1790715, Length=322, Percent_Identity=27.0186335403727, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790689, Length=343, Percent_Identity=23.3236151603499, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786268, Length=299, Percent_Identity=24.0802675585284, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38653; Mature: 38653

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITIKDVAKHANVAPSTVSRVIANSPRISQKTKERVRSSMEELGYHPNIHARSLANRST
CEEEHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
QSIGLVMPSAATKTLQNPFFPEVLRGISTKAHQNGYSLYMTTGVTEEEVLSGVIEMVQGR
CCEEEEECCHHHHHHCCCCHHHHHHHHCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
RVDGVIVLYSREDDQVVQYLRQTKFPFVVVGKPFGDASSITYVDTDNYLAGREVTKHLYN
CCCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGHRRIAFIGGSDKLAVTQDRRNGYATALMEAGIPVCEDYIARAEFMTKGGAKAVRELLQ
CCCCEEEEECCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
NEEPPTAVVVSDDMMALGVISTLSEMGLKIPEDVAVVSFNNVYIAEHSNPPLTSVEINIF
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCCCCCEEEEEEEE
GLGFEATNCLIEQISDNAPPYGKRVIVPHYLVVRQSCGQKKSKATETLESNS
EECHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MQITIKDVAKHANVAPSTVSRVIANSPRISQKTKERVRSSMEELGYHPNIHARSLANRST
CEEEHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
QSIGLVMPSAATKTLQNPFFPEVLRGISTKAHQNGYSLYMTTGVTEEEVLSGVIEMVQGR
CCEEEEECCHHHHHHCCCCHHHHHHHHCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
RVDGVIVLYSREDDQVVQYLRQTKFPFVVVGKPFGDASSITYVDTDNYLAGREVTKHLYN
CCCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGHRRIAFIGGSDKLAVTQDRRNGYATALMEAGIPVCEDYIARAEFMTKGGAKAVRELLQ
CCCCEEEEECCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
NEEPPTAVVVSDDMMALGVISTLSEMGLKIPEDVAVVSFNNVYIAEHSNPPLTSVEINIF
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCCCCCEEEEEEEE
GLGFEATNCLIEQISDNAPPYGKRVIVPHYLVVRQSCGQKKSKATETLESNS
EECHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]