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The map label for this gene is cssR [H]

Identifier: 229918194

GI number: 229918194

Start: 2428590

End: 2429252

Strand: Direct

Name: cssR [H]

Synonym: EAT1b_2474

Alternate gene names: 229918194

Gene position: 2428590-2429252 (Clockwise)

Preceding gene: 229918193

Following gene: 229918195

Centisome position: 80.96

GC content: 46.61

Gene sequence:

>663_bases
ATGTATACAATTTACTTAGTCGACGATGAAGCAAACCTAAATAAAATGCTCGTCACGTATCTAGAACAGGAAGGCTACAA
CGTTCGCTCATTTGCGGACGGGACATCTGCACAAGAAGCGATTCCAGATCAACCGGATTTATGGGTGCTCGATATCATGT
TGCCAGACTTGGATGGCTTTCAATTGTTGAAACAAATCAAAGCCGTCAATGCGAATACGCCGACGATTTTCATCTCGGCG
CGCGATGAGGATATCGACAAAATCATCGGACTCGAGATGGGTTCGGATGACTACATCGCCAAACCGTTCCTTCCAAGGGA
ACTTGTCATCCGTGTCAAAAAATTGATTGATCGTGTCTACGGTTCGAAGTCGAACGAGCATATCGAATACGGAGAGTACA
CCATTTATCCGGATAAACGTCTGATCAAGCACGGAGACGAAGAGATCGATTTGACTTCGAAAGAATTCGATTTACTGCTA
CTCTTCCTCGAACATCCGGGCTCCGCATTGTCGCGTGAGCAAATTTTAGAAGGTGTTTGGGGGAATGATTATTTCGGATC
GGACCGCGTCGTCGATGATTTGGTGCGTCGTGTCCGAAAGAAATTGCATCGCCTTGAGCTCGAAACGCTTTACGGTATCG
GCTACCGTCTCGTCAGACCATGA

Upstream 100 bases:

>100_bases
GCAATTTCGTTGCCTTCTTTTTTCTTTGACTTCATTTCTTTCCCATCATTTCACGACAATTGTTTGATATGATGAGAAAA
AACGTGTTGAGGTGACTTGA

Downstream 100 bases:

>100_bases
TGGACGCGCTTAAACCGAAACGTCTCATGTGGAAGATTTGGGTGCTCATCTTACTCATCATCGTGACGCTTGCGCTCATG
ATCTTGATTACGGTCCGTTC

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MYTIYLVDDEANLNKMLVTYLEQEGYNVRSFADGTSAQEAIPDQPDLWVLDIMLPDLDGFQLLKQIKAVNANTPTIFISA
RDEDIDKIIGLEMGSDDYIAKPFLPRELVIRVKKLIDRVYGSKSNEHIEYGEYTIYPDKRLIKHGDEEIDLTSKEFDLLL
LFLEHPGSALSREQILEGVWGNDYFGSDRVVDDLVRRVRKKLHRLELETLYGIGYRLVRP

Sequences:

>Translated_220_residues
MYTIYLVDDEANLNKMLVTYLEQEGYNVRSFADGTSAQEAIPDQPDLWVLDIMLPDLDGFQLLKQIKAVNANTPTIFISA
RDEDIDKIIGLEMGSDDYIAKPFLPRELVIRVKKLIDRVYGSKSNEHIEYGEYTIYPDKRLIKHGDEEIDLTSKEFDLLL
LFLEHPGSALSREQILEGVWGNDYFGSDRVVDDLVRRVRKKLHRLELETLYGIGYRLVRP
>Mature_220_residues
MYTIYLVDDEANLNKMLVTYLEQEGYNVRSFADGTSAQEAIPDQPDLWVLDIMLPDLDGFQLLKQIKAVNANTPTIFISA
RDEDIDKIIGLEMGSDDYIAKPFLPRELVIRVKKLIDRVYGSKSNEHIEYGEYTIYPDKRLIKHGDEEIDLTSKEFDLLL
LFLEHPGSALSREQILEGVWGNDYFGSDRVVDDLVRRVRKKLHRLELETLYGIGYRLVRP

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=37.3873873873874, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=38.0090497737557, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=33.6244541484716, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=36.036036036036, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=33.6363636363636, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.061135371179, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=35.2173913043478, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=215, Percent_Identity=33.0232558139535, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=33.0396475770925, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.0810810810811, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=31.4814814814815, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI145693140, Length=216, Percent_Identity=31.9444444444444, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=217, Percent_Identity=26.2672811059908, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=150, Percent_Identity=27.3333333333333, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=31.304347826087, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25427; Mature: 25427

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIYLVDDEANLNKMLVTYLEQEGYNVRSFADGTSAQEAIPDQPDLWVLDIMLPDLDGF
CEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCCEEEEEEECCCCCHH
QLLKQIKAVNANTPTIFISARDEDIDKIIGLEMGSDDYIAKPFLPRELVIRVKKLIDRVY
HHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GSKSNEHIEYGEYTIYPDKRLIKHGDEEIDLTSKEFDLLLLFLEHPGSALSREQILEGVW
CCCCCCCEECCCEEECCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCC
GNDYFGSDRVVDDLVRRVRKKLHRLELETLYGIGYRLVRP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MYTIYLVDDEANLNKMLVTYLEQEGYNVRSFADGTSAQEAIPDQPDLWVLDIMLPDLDGF
CEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCCCCEEEEEEECCCCCHH
QLLKQIKAVNANTPTIFISARDEDIDKIIGLEMGSDDYIAKPFLPRELVIRVKKLIDRVY
HHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GSKSNEHIEYGEYTIYPDKRLIKHGDEEIDLTSKEFDLLLLFLEHPGSALSREQILEGVW
CCCCCCCEECCCEEECCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCC
GNDYFGSDRVVDDLVRRVRKKLHRLELETLYGIGYRLVRP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]