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The map label for this gene is perR [H]

Identifier: 229918141

GI number: 229918141

Start: 2372248

End: 2372691

Strand: Direct

Name: perR [H]

Synonym: EAT1b_2421

Alternate gene names: 229918141

Gene position: 2372248-2372691 (Clockwise)

Preceding gene: 229918137

Following gene: 229918143

Centisome position: 79.08

GC content: 47.07

Gene sequence:

>444_bases
GTGGGAAGCGAAATGCTTGACCATGCTGTTCAGTCGCTCCGGGAACATGGAGTCAGAATGACGCCTCAGCGCCAGGCCAT
TTTGGAGTACCTCGTCACGGAGCATAGTCACCCGACAGCGGATGACATTTATAAGGCACTTGCCGCACGGTTTCCAAATA
TGAGTGTGGCCACTGTATATAACAACTTGCGCGTTTTTAAAGAAGTGGGTCTCGTTCAAGAGATGAACTATGGGGACGCC
TCAAGTCGTTTTGACTTTGTGACGTCGAAGCACTATCACATCATCTGTGATACGTGTGGAAAAGTCGTCGACTTTAACTA
TCCTGTATTAGATGAAATCGAATCGGTTGCATCACAATTGACTGGATTCAAAGTTGATCGTCACCGTCTTGAAGTGTACG
GAACGTGCCCGTCTTGTCAGTCTGAACAATCGCAAACACATTAA

Upstream 100 bases:

>100_bases
TGAGAAATCAGTACACTATTTATAAAGATTACTATGTAAGAAATAAGTTAATGTTCAAAACTATTTCGCATGAATTTTAT
AGAAGAAATGAGGGATTGAC

Downstream 100 bases:

>100_bases
AAAACCACATCCGACTGCTCGGATGTGGTTTTTATGTTAGTCCGTCTGTTGTGACTGACGTTTGTTATATTTCTCATCGA
ATTCTTTTCCTTCGAGTGAA

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MGSEMLDHAVQSLREHGVRMTPQRQAILEYLVTEHSHPTADDIYKALAARFPNMSVATVYNNLRVFKEVGLVQEMNYGDA
SSRFDFVTSKHYHIICDTCGKVVDFNYPVLDEIESVASQLTGFKVDRHRLEVYGTCPSCQSEQSQTH

Sequences:

>Translated_147_residues
MGSEMLDHAVQSLREHGVRMTPQRQAILEYLVTEHSHPTADDIYKALAARFPNMSVATVYNNLRVFKEVGLVQEMNYGDA
SSRFDFVTSKHYHIICDTCGKVVDFNYPVLDEIESVASQLTGFKVDRHRLEVYGTCPSCQSEQSQTH
>Mature_146_residues
GSEMLDHAVQSLREHGVRMTPQRQAILEYLVTEHSHPTADDIYKALAARFPNMSVATVYNNLRVFKEVGLVQEMNYGDAS
SRFDFVTSKHYHIICDTCGKVVDFNYPVLDEIESVASQLTGFKVDRHRLEVYGTCPSCQSEQSQTH

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16686; Mature: 16555

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSEMLDHAVQSLREHGVRMTPQRQAILEYLVTEHSHPTADDIYKALAARFPNMSVATVY
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
NNLRVFKEVGLVQEMNYGDASSRFDFVTSKHYHIICDTCGKVVDFNYPVLDEIESVASQL
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEECCCCCEECCCCCHHHHHHHHHHHH
TGFKVDRHRLEVYGTCPSCQSEQSQTH
HCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
GSEMLDHAVQSLREHGVRMTPQRQAILEYLVTEHSHPTADDIYKALAARFPNMSVATVY
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
NNLRVFKEVGLVQEMNYGDASSRFDFVTSKHYHIICDTCGKVVDFNYPVLDEIESVASQL
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEECCCCCEECCCCCHHHHHHHHHHHH
TGFKVDRHRLEVYGTCPSCQSEQSQTH
HCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]