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The map label for this gene is map [H]

Identifier: 229918089

GI number: 229918089

Start: 2321259

End: 2322008

Strand: Direct

Name: map [H]

Synonym: EAT1b_2369

Alternate gene names: 229918089

Gene position: 2321259-2322008 (Clockwise)

Preceding gene: 229918088

Following gene: 229918096

Centisome position: 77.38

GC content: 48.53

Gene sequence:

>750_bases
ATGCTAGATTATGATTACGATGCATTGCGCGAAATCGGGCGAATCGTCGCACTTGCGCGAGATGAAATGGCGAAAGCCGT
CAAGCCCGGTATGACGACAAAAGAATTAGATGCGATCGGGCAACGTATTTTAGAAGAAGAAGGTGCAGCTTCTGCACCGA
TTACGATGTACGAATTTCCAGGTTACACATGTATCTCGCTCAATGACGTTGCTGCCCATGGTATTCCGGGAGATGAAGTC
ATTCAAGAAGGAGATATCGTCAATGTCGACGTCTCCGCTGTGAAGGATGGGTATTATGCCGATACGGGACGCACTGTGAT
TGCGGGAGCGGCGAAGTCACCCCAGCACGAACGTTTGGTCGAAGTATCCTTGACTTCATTGGAAGCTGGTCTCAGCAAAG
TTAAAGCGGGCGTGAAAGTCAATCAGATTGGGAAAGCGATTTACGCCGACGCGAGAAAGAATGGATTCACAGTCATCCGG
AACTTGGCCGGACACGGTCTCGGTCGGACATTGCACGGGGAGCCGGAAACGATCTCGAACTATTATAGTCGTGAAGAAAA
TCAACTCTTGAAAGCCGGGCAAGTGATTGCTGTTGAGACGTTCATCTCGACAAAGGATGAAATCGTCTATCAATCGGAAG
AGGATGGTTGGACACTCTTCACTCCGAACAAGAGTCTTGTTTCGCAGTTCGAGCATACAGTTGTTGTCACAGAAGATGGA
TATGAAGTGTTAACGGGATCGTTCCGTTAA

Upstream 100 bases:

>100_bases
CGTTCAGCTATCCGTTACCGGACGGCATGTTCTTATTTGCCGACATCTCTGAAGAATATTTATATCAAAATCGATTATTG
GATTGAAAGGAAGATGGACG

Downstream 100 bases:

>100_bases
CGTAAAAAGGTGTGGTTCTCGTGAACCGCACCTTTTTTCATGTTTGCAATGTAATCACTTCTTCGCGTAACCGTTCAATC
ACATTCCAATCTGGTTGTAC

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLDYDYDALREIGRIVALARDEMAKAVKPGMTTKELDAIGQRILEEEGAASAPITMYEFPGYTCISLNDVAAHGIPGDEV
IQEGDIVNVDVSAVKDGYYADTGRTVIAGAAKSPQHERLVEVSLTSLEAGLSKVKAGVKVNQIGKAIYADARKNGFTVIR
NLAGHGLGRTLHGEPETISNYYSREENQLLKAGQVIAVETFISTKDEIVYQSEEDGWTLFTPNKSLVSQFEHTVVVTEDG
YEVLTGSFR

Sequences:

>Translated_249_residues
MLDYDYDALREIGRIVALARDEMAKAVKPGMTTKELDAIGQRILEEEGAASAPITMYEFPGYTCISLNDVAAHGIPGDEV
IQEGDIVNVDVSAVKDGYYADTGRTVIAGAAKSPQHERLVEVSLTSLEAGLSKVKAGVKVNQIGKAIYADARKNGFTVIR
NLAGHGLGRTLHGEPETISNYYSREENQLLKAGQVIAVETFISTKDEIVYQSEEDGWTLFTPNKSLVSQFEHTVVVTEDG
YEVLTGSFR
>Mature_249_residues
MLDYDYDALREIGRIVALARDEMAKAVKPGMTTKELDAIGQRILEEEGAASAPITMYEFPGYTCISLNDVAAHGIPGDEV
IQEGDIVNVDVSAVKDGYYADTGRTVIAGAAKSPQHERLVEVSLTSLEAGLSKVKAGVKVNQIGKAIYADARKNGFTVIR
NLAGHGLGRTLHGEPETISNYYSREENQLLKAGQVIAVETFISTKDEIVYQSEEDGWTLFTPNKSLVSQFEHTVVVTEDG
YEVLTGSFR

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=243, Percent_Identity=34.156378600823, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI40385867, Length=242, Percent_Identity=31.8181818181818, Blast_Score=141, Evalue=7e-34,
Organism=Escherichia coli, GI1786364, Length=244, Percent_Identity=40.5737704918033, Blast_Score=184, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=31.9838056680162, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=35.4838709677419, Blast_Score=152, Evalue=5e-38,
Organism=Drosophila melanogaster, GI21355531, Length=243, Percent_Identity=32.9218106995885, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24583427, Length=243, Percent_Identity=34.156378600823, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27091; Mature: 27091

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYDYDALREIGRIVALARDEMAKAVKPGMTTKELDAIGQRILEEEGAASAPITMYEFP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC
GYTCISLNDVAAHGIPGDEVIQEGDIVNVDVSAVKDGYYADTGRTVIAGAAKSPQHERLV
CEEEEEECCHHHCCCCHHHHHCCCCEEEEEHHHHCCCEECCCCCEEEEECCCCCCHHHHH
EVSLTSLEAGLSKVKAGVKVNQIGKAIYADARKNGFTVIRNLAGHGLGRTLHGEPETISN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHH
YYSREENQLLKAGQVIAVETFISTKDEIVYQSEEDGWTLFTPNKSLVSQFEHTVVVTEDG
HHHHHHHHHHHCCCEEEEEEHHCCCCCEEEECCCCCEEEECCCHHHHHHHHCEEEEECCC
YEVLTGSFR
CEEECCCCC
>Mature Secondary Structure
MLDYDYDALREIGRIVALARDEMAKAVKPGMTTKELDAIGQRILEEEGAASAPITMYEFP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC
GYTCISLNDVAAHGIPGDEVIQEGDIVNVDVSAVKDGYYADTGRTVIAGAAKSPQHERLV
CEEEEEECCHHHCCCCHHHHHCCCCEEEEEHHHHCCCEECCCCCEEEEECCCCCCHHHHH
EVSLTSLEAGLSKVKAGVKVNQIGKAIYADARKNGFTVIRNLAGHGLGRTLHGEPETISN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHH
YYSREENQLLKAGQVIAVETFISTKDEIVYQSEEDGWTLFTPNKSLVSQFEHTVVVTEDG
HHHHHHHHHHHCCCEEEEEEHHCCCCCEEEECCCCCEEEECCCHHHHHHHHCEEEEECCC
YEVLTGSFR
CEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA