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The map label for this gene is yesM [H]

Identifier: 229918055

GI number: 229918055

Start: 2288132

End: 2289883

Strand: Direct

Name: yesM [H]

Synonym: EAT1b_2334

Alternate gene names: 229918055

Gene position: 2288132-2289883 (Clockwise)

Preceding gene: 229918054

Following gene: 229918056

Centisome position: 76.27

GC content: 47.72

Gene sequence:

>1752_bases
GTGAATAGCATTCGGACAAAGTTAACGGGAATGATTGCATTAACCATCATCGTGCCAGTCATTATCGCGACAATCATTTC
ATTTTGGTATGTGGAGGATCGAGAACGTGAACGCGGTCTAGAAATGACGGAATGGTCGCTTGAACGGGGGACGCGTCAGA
TGGAACGCTATATCTCTGACTTAAGTCGCTTGCCGACTAGCCTATACGCGGATCGTGACGTTTTGGACATATTGGAATAC
GGACCGGGACTGTCGTTAAGAGAAACGGAGATTGAAGTGCGACGAGCGCTCCTCGCGATGTATTTGTCCCGGGAAGACGT
GGCGCAAATTCAGCTGTTGATGCTTGAAGACATGGATTCATTCGCAGCGTATAAAATGAAAGTATCACCACGTTCCAAAA
AAGAGCCGAGCGCTGTCCAACGACAGTTGTTGAATAATCCGAAAAGTCGCGTCCTGCTTGAAGCGTCACATCCGCTCATC
CCGTATCATGATTTCGGACCAATCATGACGCAAGAAGATGTCGTCACCCTCCATTTCAGACTCGACAAAATTGAAACGAA
CGAACCGCTCGCGATTCTGTCACTCGATATCCCGGAAGATTTGTTCATCGGACAGTTGGCTTCTCTTCAAAATAGTCCGG
AGGAAAGTCTATGGTTCGTTGGTGAGGACAATCGTGTGTTCGCCCATCTTGGAGATGGCGAGATTCCTTCTTCGTTTCAA
CCGAGGTCGCTCTCGACCGATGGAAAACATCATCAAATCACGAAAACGTTTGAGTTCGACCATCAGCAGTTCTATGTCGG
GAAGTCGATTCCAGATCAGCTCTTGACGGAGCCGGCTTCACGAACATCGTTCATTATTTTGTTAGTCGGAATCATCTCCC
TCATTCTGGCGTTGATCGGTGCCACGTACGCCTCGATGAAACTGACGACTCCAATCAAGACGTTGACCTCGAACATTTGG
CGAATTGAGCAAGGCGATATGACGGTCTCGTTCGATTCCCTTGGAAATGATGAGTTCGGCGTACTCGGGAGACAGTTCAA
GCGGATGATTGAGCGAATCGATGATCTGATTCAACGGGAGTATAAGCTTGCCTTAGAGAACCGAACAAATGAACTACGTG
CCTTACAGGCGCAAACCAATCCGCATTTCTTATTCAATGCGCTACAGTCGATCGGTACACTCGCTTTAAAGGGAGATGGA
AAAACCGTCTATCGATTGATCACACAACTCTCTTCGATGATGCGATATACGATGCATCCTGAAGAGTCGATGGTCACGCT
AAAGAGAGAAATCGAGCATTTGAACTCATATATTCGCCTGCAAGACGTACGTTTTCCAAATCAGTTTCAAGTGAACGTTT
CAGTCCCTCAGGACCTCCATGAACTGATTGTTCCTAAGATGATTTTACAGCCGCTCGCAGAGAACTTTTTCAAACATGGG
TTCGAACGAGACGGCTCGGCGTTGGCGAATCGATTTGACGTGATGATTTGGATGGAAGGGGCGACACTCGTGATTCGCTG
TGAGAACAGTGGACGTTCCTTGACGACGGAAGAGTGGGAACGGGTCATGTCACGGATTGAACAAGGGGACTCGACATTTT
ATGACACAGAGGGCACAGGATTACGAAACATTCGTGATCGACTCATGTTAAACTATAATCGGGAGGCAGAATTTATGTTG
GCTACACCTGAAACAGGCGGTTTTCGAATCATGATGCGTTTCCCGGCAACGGATGAAGGGGTGGCATCATGA

Upstream 100 bases:

>100_bases
TCGCGTAATCCTTGTTTCGAAAGAAACGAGGATTCTTTTTTAGGATTATTGCAAACGTTTGCATAGTGCGTGATATACTC
ATGAGGTAGGGGGGATAGCG

Downstream 100 bases:

>100_bases
CGAAAGTGTTGATTGTAGATGATGAATCTCCGGTAAGGGAAGCGGTAAAATTACTCGGCGAATGGGAACGGTTCGGTGTG
AAGGCCGTACTCGAGGCGAA

Product: sensor with HAMP domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MNSIRTKLTGMIALTIIVPVIIATIISFWYVEDRERERGLEMTEWSLERGTRQMERYISDLSRLPTSLYADRDVLDILEY
GPGLSLRETEIEVRRALLAMYLSREDVAQIQLLMLEDMDSFAAYKMKVSPRSKKEPSAVQRQLLNNPKSRVLLEASHPLI
PYHDFGPIMTQEDVVTLHFRLDKIETNEPLAILSLDIPEDLFIGQLASLQNSPEESLWFVGEDNRVFAHLGDGEIPSSFQ
PRSLSTDGKHHQITKTFEFDHQQFYVGKSIPDQLLTEPASRTSFIILLVGIISLILALIGATYASMKLTTPIKTLTSNIW
RIEQGDMTVSFDSLGNDEFGVLGRQFKRMIERIDDLIQREYKLALENRTNELRALQAQTNPHFLFNALQSIGTLALKGDG
KTVYRLITQLSSMMRYTMHPEESMVTLKREIEHLNSYIRLQDVRFPNQFQVNVSVPQDLHELIVPKMILQPLAENFFKHG
FERDGSALANRFDVMIWMEGATLVIRCENSGRSLTTEEWERVMSRIEQGDSTFYDTEGTGLRNIRDRLMLNYNREAEFML
ATPETGGFRIMMRFPATDEGVAS

Sequences:

>Translated_583_residues
MNSIRTKLTGMIALTIIVPVIIATIISFWYVEDRERERGLEMTEWSLERGTRQMERYISDLSRLPTSLYADRDVLDILEY
GPGLSLRETEIEVRRALLAMYLSREDVAQIQLLMLEDMDSFAAYKMKVSPRSKKEPSAVQRQLLNNPKSRVLLEASHPLI
PYHDFGPIMTQEDVVTLHFRLDKIETNEPLAILSLDIPEDLFIGQLASLQNSPEESLWFVGEDNRVFAHLGDGEIPSSFQ
PRSLSTDGKHHQITKTFEFDHQQFYVGKSIPDQLLTEPASRTSFIILLVGIISLILALIGATYASMKLTTPIKTLTSNIW
RIEQGDMTVSFDSLGNDEFGVLGRQFKRMIERIDDLIQREYKLALENRTNELRALQAQTNPHFLFNALQSIGTLALKGDG
KTVYRLITQLSSMMRYTMHPEESMVTLKREIEHLNSYIRLQDVRFPNQFQVNVSVPQDLHELIVPKMILQPLAENFFKHG
FERDGSALANRFDVMIWMEGATLVIRCENSGRSLTTEEWERVMSRIEQGDSTFYDTEGTGLRNIRDRLMLNYNREAEFML
ATPETGGFRIMMRFPATDEGVAS
>Mature_583_residues
MNSIRTKLTGMIALTIIVPVIIATIISFWYVEDRERERGLEMTEWSLERGTRQMERYISDLSRLPTSLYADRDVLDILEY
GPGLSLRETEIEVRRALLAMYLSREDVAQIQLLMLEDMDSFAAYKMKVSPRSKKEPSAVQRQLLNNPKSRVLLEASHPLI
PYHDFGPIMTQEDVVTLHFRLDKIETNEPLAILSLDIPEDLFIGQLASLQNSPEESLWFVGEDNRVFAHLGDGEIPSSFQ
PRSLSTDGKHHQITKTFEFDHQQFYVGKSIPDQLLTEPASRTSFIILLVGIISLILALIGATYASMKLTTPIKTLTSNIW
RIEQGDMTVSFDSLGNDEFGVLGRQFKRMIERIDDLIQREYKLALENRTNELRALQAQTNPHFLFNALQSIGTLALKGDG
KTVYRLITQLSSMMRYTMHPEESMVTLKREIEHLNSYIRLQDVRFPNQFQVNVSVPQDLHELIVPKMILQPLAENFFKHG
FERDGSALANRFDVMIWMEGATLVIRCENSGRSLTTEEWERVMSRIEQGDSTFYDTEGTGLRNIRDRLMLNYNREAEFML
ATPETGGFRIMMRFPATDEGVAS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=214, Percent_Identity=30.8411214953271, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788723, Length=185, Percent_Identity=28.1081081081081, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66891; Mature: 66891

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIRTKLTGMIALTIIVPVIIATIISFWYVEDRERERGLEMTEWSLERGTRQMERYISD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LSRLPTSLYADRDVLDILEYGPGLSLRETEIEVRRALLAMYLSREDVAQIQLLMLEDMDS
HHHCCHHHHCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
FAAYKMKVSPRSKKEPSAVQRQLLNNPKSRVLLEASHPLIPYHDFGPIMTQEDVVTLHFR
HHEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEE
LDKIETNEPLAILSLDIPEDLFIGQLASLQNSPEESLWFVGEDNRVFAHLGDGEIPSSFQ
EEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCC
PRSLSTDGKHHQITKTFEFDHQQFYVGKSIPDQLLTEPASRTSFIILLVGIISLILALIG
CCCCCCCCCCCEEEEEEECCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
ATYASMKLTTPIKTLTSNIWRIEQGDMTVSFDSLGNDEFGVLGRQFKRMIERIDDLIQRE
CHHHHEEECCHHHHHHHHHEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKLALENRTNELRALQAQTNPHFLFNALQSIGTLALKGDGKTVYRLITQLSSMMRYTMHP
HHHHHHCCCCHHHEECCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHCCC
EESMVTLKREIEHLNSYIRLQDVRFPNQFQVNVSVPQDLHELIVPKMILQPLAENFFKHG
HHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
FERDGSALANRFDVMIWMEGATLVIRCENSGRSLTTEEWERVMSRIEQGDSTFYDTEGTG
CCCCCHHHHHHEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCC
LRNIRDRLMLNYNREAEFMLATPETGGFRIMMRFPATDEGVAS
HHHHHHHHEECCCCCCEEEEECCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNSIRTKLTGMIALTIIVPVIIATIISFWYVEDRERERGLEMTEWSLERGTRQMERYISD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LSRLPTSLYADRDVLDILEYGPGLSLRETEIEVRRALLAMYLSREDVAQIQLLMLEDMDS
HHHCCHHHHCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
FAAYKMKVSPRSKKEPSAVQRQLLNNPKSRVLLEASHPLIPYHDFGPIMTQEDVVTLHFR
HHEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEE
LDKIETNEPLAILSLDIPEDLFIGQLASLQNSPEESLWFVGEDNRVFAHLGDGEIPSSFQ
EEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCC
PRSLSTDGKHHQITKTFEFDHQQFYVGKSIPDQLLTEPASRTSFIILLVGIISLILALIG
CCCCCCCCCCCEEEEEEECCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
ATYASMKLTTPIKTLTSNIWRIEQGDMTVSFDSLGNDEFGVLGRQFKRMIERIDDLIQRE
CHHHHEEECCHHHHHHHHHEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKLALENRTNELRALQAQTNPHFLFNALQSIGTLALKGDGKTVYRLITQLSSMMRYTMHP
HHHHHHCCCCHHHEECCCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHCCC
EESMVTLKREIEHLNSYIRLQDVRFPNQFQVNVSVPQDLHELIVPKMILQPLAENFFKHG
HHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
FERDGSALANRFDVMIWMEGATLVIRCENSGRSLTTEEWERVMSRIEQGDSTFYDTEGTG
CCCCCHHHHHHEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCC
LRNIRDRLMLNYNREAEFMLATPETGGFRIMMRFPATDEGVAS
HHHHHHHHEECCCCCCEEEEECCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]