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The map label for this gene is ykkD [H]

Identifier: 229918013

GI number: 229918013

Start: 2248773

End: 2249087

Strand: Direct

Name: ykkD [H]

Synonym: EAT1b_2292

Alternate gene names: 229918013

Gene position: 2248773-2249087 (Clockwise)

Preceding gene: 229918012

Following gene: 229918014

Centisome position: 74.96

GC content: 43.49

Gene sequence:

>315_bases
ATGAGTTGGGTTTATCTGATTGGAGCGGGAATTGCTGAAATGACAGCCGTTTTCTTTATGGGGAAATCGAAAGGATACCA
GATTTTGAAATGGTCGATTGCATCGATTTTATCTTTTGCGCTCAGCTTCTATTGGTTATCAAAATCACTTGAGGTCATTC
CTCTTAGTCTTGCCTATTCCATCTGGGTAGGTATCGGCGCGGCCGGCGGCGTCATTTTAGGGATGCTCTATTTGAACGAA
TCGAAAAGTCGCTGGCGTATCTTTTATTTGACGTTGATTATCGGGAGTGTGGTCGGATTAAAAGTTGTGGCCTAA

Upstream 100 bases:

>100_bases
TCTTATTTGACGAGGGGCTTAATGGATGGAAACTGATCCTTGTGACGACGTTGATTGTCGGTATCATCGGATTGAAGCAA
GTGACAGGAGGGGAAGAGGC

Downstream 100 bases:

>100_bases
AGGATTGAAATGTGCTGAAAACGGGAATTTAATAATTCAGATTATGAGATGAAAGAAAGGGGCGGAAAACGATGCATCTT
GTCGAGTTGCAATCCGAACG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSWVYLIGAGIAEMTAVFFMGKSKGYQILKWSIASILSFALSFYWLSKSLEVIPLSLAYSIWVGIGAAGGVILGMLYLNE
SKSRWRIFYLTLIIGSVVGLKVVA

Sequences:

>Translated_104_residues
MSWVYLIGAGIAEMTAVFFMGKSKGYQILKWSIASILSFALSFYWLSKSLEVIPLSLAYSIWVGIGAAGGVILGMLYLNE
SKSRWRIFYLTLIIGSVVGLKVVA
>Mature_103_residues
SWVYLIGAGIAEMTAVFFMGKSKGYQILKWSIASILSFALSFYWLSKSLEVIPLSLAYSIWVGIGAAGGVILGMLYLNES
KSRWRIFYLTLIIGSVVGLKVVA

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=101, Percent_Identity=32.6732673267327, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11433; Mature: 11302

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWVYLIGAGIAEMTAVFFMGKSKGYQILKWSIASILSFALSFYWLSKSLEVIPLSLAYS
CCEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
IWVGIGAAGGVILGMLYLNESKSRWRIFYLTLIIGSVVGLKVVA
HHHHCCCCHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHEEEEC
>Mature Secondary Structure 
SWVYLIGAGIAEMTAVFFMGKSKGYQILKWSIASILSFALSFYWLSKSLEVIPLSLAYS
CEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
IWVGIGAAGGVILGMLYLNESKSRWRIFYLTLIIGSVVGLKVVA
HHHHCCCCHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA