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The map label for this gene is sugE [H]

Identifier: 229918012

GI number: 229918012

Start: 2248432

End: 2248776

Strand: Direct

Name: sugE [H]

Synonym: EAT1b_2291

Alternate gene names: 229918012

Gene position: 2248432-2248776 (Clockwise)

Preceding gene: 229918011

Following gene: 229918013

Centisome position: 74.95

GC content: 50.43

Gene sequence:

>345_bases
ATGAGTAAAGAGAAGGGTGCATGGATTTCCCTCCTGTTTGCAGGACTACTCGAAATCGTCTGGGCGACGACGATGAAGCT
GTCTGAAGGCTTCACGGTTTTAGGTCCGACATTGTGGACGATCGTGTTATTGATTCTTAGTTTCGGATTATTGGCGAAAG
CGTTTCGGACGCTCCCTGCCGGTACGGGGTACGCCGTATTCACAGGAATCGGAGCGGTCGGCACAGTCATAGTTGGTGCC
TTCTTATTTGACGAGGGGCTTAATGGATGGAAACTGATCCTTGTGACGACGTTGATTGTCGGTATCATCGGATTGAAGCA
AGTGACAGGAGGGGAAGAGGCATGA

Upstream 100 bases:

>100_bases
TTTTTAGATGGCGCCTTACTGTCGTTATTCACATTTGAAGAGGACCGGGAGATGCGACAACAAGCTGCGTTTCGAATTTT
CAAGAAAGGGGTGGGTTGGG

Downstream 100 bases:

>100_bases
GTTGGGTTTATCTGATTGGAGCGGGAATTGCTGAAATGACAGCCGTTTTCTTTATGGGGAAATCGAAAGGATACCAGATT
TTGAAATGGTCGATTGCATC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSKEKGAWISLLFAGLLEIVWATTMKLSEGFTVLGPTLWTIVLLILSFGLLAKAFRTLPAGTGYAVFTGIGAVGTVIVGA
FLFDEGLNGWKLILVTTLIVGIIGLKQVTGGEEA

Sequences:

>Translated_114_residues
MSKEKGAWISLLFAGLLEIVWATTMKLSEGFTVLGPTLWTIVLLILSFGLLAKAFRTLPAGTGYAVFTGIGAVGTVIVGA
FLFDEGLNGWKLILVTTLIVGIIGLKQVTGGEEA
>Mature_113_residues
SKEKGAWISLLFAGLLEIVWATTMKLSEGFTVLGPTLWTIVLLILSFGLLAKAFRTLPAGTGYAVFTGIGAVGTVIVGAF
LFDEGLNGWKLILVTTLIVGIIGLKQVTGGEEA

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=103, Percent_Identity=48.5436893203884, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11986; Mature: 11854

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKGAWISLLFAGLLEIVWATTMKLSEGFTVLGPTLWTIVLLILSFGLLAKAFRTLPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCC
GTGYAVFTGIGAVGTVIVGAFLFDEGLNGWKLILVTTLIVGIIGLKQVTGGEEA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKEKGAWISLLFAGLLEIVWATTMKLSEGFTVLGPTLWTIVLLILSFGLLAKAFRTLPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCC
GTGYAVFTGIGAVGTVIVGAFLFDEGLNGWKLILVTTLIVGIIGLKQVTGGEEA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]