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The map label for this gene is nagA [H]

Identifier: 229917975

GI number: 229917975

Start: 2208270

End: 2209418

Strand: Direct

Name: nagA [H]

Synonym: EAT1b_2254

Alternate gene names: 229917975

Gene position: 2208270-2209418 (Clockwise)

Preceding gene: 229917974

Following gene: 229917976

Centisome position: 73.61

GC content: 51.78

Gene sequence:

>1149_bases
ATGGGGACATTGATCAATGCTCGTATCGTGTCAGCAGAACAAACATGGGAACGTGGATATATCAGATGGAATGGTCAAAC
GATTGATGAGATTGGATCGATGGAACAGTTTGAACAACAGGATGAGCATGTGATTGATGTCGCTGGAGCACTCGTGACAC
CGGGTCTCATCGATGTGCATATCCATGGGGGATATGAAGTCGATACGATGGATGCGGATGAATCAAAACTTCGGCAGTTG
AGTAACGACATGCTACAAGAAGGCGTCACTTCTTTTTTTGCGACGACCATCACGCAGTCAAAAGAAGCGATTGAGCATGC
CTTGAAGGCGGTCCGAAACGTCATCGAAGCGCAGGATACGACACTCATCGGGATTCACTTGGAAGGTCCTTTCGTCAACG
TGGAGATGGCTGGGGCACAGCCGGCGGAATATATTATCGACCCGGACGCCGAGCAGTTCCGAAAATGGCAAGAGCTCGCC
GGCGGTCATATCCGCCTCGTTACGTATGCACCGGAACGGCCAGGTGCACGTGCATTTGAAGCGGTACTTCGCGAAACCGG
TGCGATCGGTTCAGCGGGCCATACGAGCGCGACATTTGAAGAGAACAAGCAGGCGGGCGTCAAACACGGGACGCATCTTT
ATAACCAAATGCGTGGGTTACATCATCGAGAACCCGGAACGGTAGGCTATTGTCTCTTAGAGGGTGGAGTCATCGCGGAA
ATCATTCCGGATGGGATCCATAGTCGTCCGGAGATGGTCGACTTCGCGTTTCGCTTAAAAGGAGCAGATGAACTTGTCGT
CATCACGGATGCGATGCGAGCAAAAGGACTGCCGGACGGACAATATGAGCTTGGCGGCCAACCGGTCATCGTAGCGGACG
GGGCTGCGCGACTTCAAGCCGGGAACCTTGCGGGCAGTGTGTTGACGATGGACGCCGCATTCCGAAACATTCAGGCATAT
ACGGGATGTACGGTGGAAGAAGCGGTAAAAATGACCTCGACGAATGCGGCCAAAGAATTCGGGTTGACGACAAAAGGCGA
TATCAAATCGGGGTTTGATGCAGACTTTGTCGTTTGGGATGACACGACACATGTTCAGATGACTTTCGTCAAAGGTCGAA
TCGTATATAAACGGGAGGAACAAAGATGA

Upstream 100 bases:

>100_bases
CAAATGTGAACAATCTTTTATTTATTTAAAATTGGTCTATACAACTATACTTTTATCCGATATGATAACATGGAGGAAAA
CAAAAAGGAGTGGTGAACCG

Downstream 100 bases:

>100_bases
ATGTACTAGTCGCAAAGACGGCGAACGACGCGGAACGCATCGCCTATACGCTAATCAAAGAACGGATTTCAGGGAAACAT
GACTTTGTACTCGGTCTCGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MGTLINARIVSAEQTWERGYIRWNGQTIDEIGSMEQFEQQDEHVIDVAGALVTPGLIDVHIHGGYEVDTMDADESKLRQL
SNDMLQEGVTSFFATTITQSKEAIEHALKAVRNVIEAQDTTLIGIHLEGPFVNVEMAGAQPAEYIIDPDAEQFRKWQELA
GGHIRLVTYAPERPGARAFEAVLRETGAIGSAGHTSATFEENKQAGVKHGTHLYNQMRGLHHREPGTVGYCLLEGGVIAE
IIPDGIHSRPEMVDFAFRLKGADELVVITDAMRAKGLPDGQYELGGQPVIVADGAARLQAGNLAGSVLTMDAAFRNIQAY
TGCTVEEAVKMTSTNAAKEFGLTTKGDIKSGFDADFVVWDDTTHVQMTFVKGRIVYKREEQR

Sequences:

>Translated_382_residues
MGTLINARIVSAEQTWERGYIRWNGQTIDEIGSMEQFEQQDEHVIDVAGALVTPGLIDVHIHGGYEVDTMDADESKLRQL
SNDMLQEGVTSFFATTITQSKEAIEHALKAVRNVIEAQDTTLIGIHLEGPFVNVEMAGAQPAEYIIDPDAEQFRKWQELA
GGHIRLVTYAPERPGARAFEAVLRETGAIGSAGHTSATFEENKQAGVKHGTHLYNQMRGLHHREPGTVGYCLLEGGVIAE
IIPDGIHSRPEMVDFAFRLKGADELVVITDAMRAKGLPDGQYELGGQPVIVADGAARLQAGNLAGSVLTMDAAFRNIQAY
TGCTVEEAVKMTSTNAAKEFGLTTKGDIKSGFDADFVVWDDTTHVQMTFVKGRIVYKREEQR
>Mature_381_residues
GTLINARIVSAEQTWERGYIRWNGQTIDEIGSMEQFEQQDEHVIDVAGALVTPGLIDVHIHGGYEVDTMDADESKLRQLS
NDMLQEGVTSFFATTITQSKEAIEHALKAVRNVIEAQDTTLIGIHLEGPFVNVEMAGAQPAEYIIDPDAEQFRKWQELAG
GHIRLVTYAPERPGARAFEAVLRETGAIGSAGHTSATFEENKQAGVKHGTHLYNQMRGLHHREPGTVGYCLLEGGVIAEI
IPDGIHSRPEMVDFAFRLKGADELVVITDAMRAKGLPDGQYELGGQPVIVADGAARLQAGNLAGSVLTMDAAFRNIQAYT
GCTVEEAVKMTSTNAAKEFGLTTKGDIKSGFDADFVVWDDTTHVQMTFVKGRIVYKREEQR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=437, Percent_Identity=31.8077803203661, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI224922791, Length=430, Percent_Identity=31.8604651162791, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1786892, Length=335, Percent_Identity=31.3432835820896, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=386, Percent_Identity=31.8652849740933, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI19920392, Length=350, Percent_Identity=32.2857142857143, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281361140, Length=363, Percent_Identity=31.6804407713499, Blast_Score=158, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41800; Mature: 41668

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLINARIVSAEQTWERGYIRWNGQTIDEIGSMEQFEQQDEHVIDVAGALVTPGLIDVH
CCCEEEEEEEECHHHHHCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
IHGGYEVDTMDADESKLRQLSNDMLQEGVTSFFATTITQSKEAIEHALKAVRNVIEAQDT
EECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLIGIHLEGPFVNVEMAGAQPAEYIIDPDAEQFRKWQELAGGHIRLVTYAPERPGARAFE
EEEEEEECCCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
AVLRETGAIGSAGHTSATFEENKQAGVKHGTHLYNQMRGLHHREPGTVGYCLLEGGVIAE
HHHHHHCCCCCCCCCCCCHHCCHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEE
IIPDGIHSRPEMVDFAFRLKGADELVVITDAMRAKGLPDGQYELGGQPVIVADGAARLQA
ECCCCCCCCCHHEEHEEEECCCCCEEEEECHHHHCCCCCCCEECCCCEEEEECCCHHEEC
GNLAGSVLTMDAAFRNIQAYTGCTVEEAVKMTSTNAAKEFGLTTKGDIKSGFDADFVVWD
CCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEC
DTTHVQMTFVKGRIVYKREEQR
CCCEEEEEEEEEEEEEEECCCC
>Mature Secondary Structure 
GTLINARIVSAEQTWERGYIRWNGQTIDEIGSMEQFEQQDEHVIDVAGALVTPGLIDVH
CCEEEEEEEECHHHHHCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
IHGGYEVDTMDADESKLRQLSNDMLQEGVTSFFATTITQSKEAIEHALKAVRNVIEAQDT
EECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLIGIHLEGPFVNVEMAGAQPAEYIIDPDAEQFRKWQELAGGHIRLVTYAPERPGARAFE
EEEEEEECCCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
AVLRETGAIGSAGHTSATFEENKQAGVKHGTHLYNQMRGLHHREPGTVGYCLLEGGVIAE
HHHHHHCCCCCCCCCCCCHHCCHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEE
IIPDGIHSRPEMVDFAFRLKGADELVVITDAMRAKGLPDGQYELGGQPVIVADGAARLQA
ECCCCCCCCCHHEEHEEEECCCCCEEEEECHHHHCCCCCCCEECCCCEEEEECCCHHEEC
GNLAGSVLTMDAAFRNIQAYTGCTVEEAVKMTSTNAAKEFGLTTKGDIKSGFDADFVVWD
CCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEC
DTTHVQMTFVKGRIVYKREEQR
CCCEEEEEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA